Ascites And Renal Dysfunction In Liver Disease

There has been very little written on the interaction of the liverand kidney. This book addresses the increasing incidence andsignificance of diseases, such as ascites, renal dysfunction,cirrhosis and hypertension where both organs are involved. This textbook is essential, even for confirmed practitioners andcontains current information regarding treatment and therapy forpatients with cirrhosis and ascites, clearly and effectivelypresented by the top international experts within this field. The second edition is entirely revised and updated and placesgreater emphasis on therapy.

Ascites and Renal Dysfunction in Liver Disease is the only text of its kind to focus on the clinical management of ascites and related disorders in patients with chronic liver disease. Containing the contributions of some 55 renowned experts, this text provides an up-to-date, all-embracing examination of the physiologic and pathophysiologic relationships between liver disease and the kidney. Clear and comprehensive in nature, this major text includes an exhaustive description of all pathophysiologic mechanisms relevant to our understanding of renal dysfunction and ascites formation in cirrhosis. Current information regarding treatment and therapy for patients with cirrhosis and ascites is clearly and effectively presented. From pathogenesis to clinical management, and from theory to practice, this authoritative exploration of the subject is a unique and invaluable reference tool for the gastroenterologist, hepatologist, and nephrologist alike.

In this issue of Clinics in Liver Disease, guest editor Dr. David Bernstein brings his considerable expertise to the topic of The Liver and Renal Disease. The presence of liver disease in patients with chronic renal disease makes the management of both conditions more challenging. In this issue, top experts in the field address many aspects of the treatment and management of these co-existing conditions. Contains 13 relevant, practice-oriented topics including hyponatremia in cirrhosis; pathophysiology of hepatorenal syndrome; definitions, diagnosis, and management of hepatorenal syndrome; renal replacement therapy in patients with acute liver failure and end-stage cirrhosis awaiting liver transplant; simultaneous liver/kidney transplantation; and more. Provides in-depth clinical reviews on the liver and renal disease, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

At the cutting edge of pathomechanisms and treatment strategies Ascites is the most frequent and hepatorenal syndrome the most lethal complication in liver cirrhosis. In recent years, major progress has been made regarding effective treatment of these complications, thus reducing mortality in patients. This publication highlights and critically appraises recent achievements and novel advances, and at the same time provides the background needed to grasp novel concepts. Topics treated include complications of paracentesis, the right choice of plasma expanders, and selection of patients who will experience survival benefit from transjugular intrahepatic portosystemic shunt. Hepatorenal syndrome, on the other hand, is responsible for a broad spectrum of manifestations caused by acute kidney injury, which until recently was considered a lethal condition. Drug treatments to improve renal function and prolong survival are therefore also discussed, including important issues for clinical outcome which are still under debate. Moreover, the role of combined kidney-liver transplantation versus conventional liver-only transplantation is addressed, as well as the use of vaptans in hyponatremia and their controversial role in the treatment of ascites. Renowned experts share their knowledge and expertise and provide an international perspective. Their contributions include up-to-date references and a bullet-point summary, making this publication most valuable for practitioners, clinicians and scientists in the field.

Continuous Renal Replacement Therapy (CRRT) is the standard of care for management of critically ill patients with acute renal failure. Part of the Pittsburgh Critical Care series, Continuous Renal Replacement Therapy provides concise, evidence-based, bedside guidance about this treatment modality, offering quick reference answers to clinicians' questions about treatments and situations encountered in daily practice. Organized into sections on theory, practice, special situations, and organizational issues, this volume provides a complete view of CRRT theory and practice. Tables summarize and highlight key points, and key studies and trials are included in each chapter. The second edition has been updated to include a new chapter on the use of biomarkers to aid in patient selection and timing, extensive revisions on terminology and nomenclature to match current standards, and the most up-to-date information on newly developed CRRT machines.

This book is contributed by worldwide experts in the field of liver diseases. It comprises of 3 sections and 6 chapters to introduce the intra-abdominal hypertension and abdominal compartment syndrome in chronic liver diseases, ascites with hyponatremia, acute kidney injury, portal vein thrombosis, spontaneous bacterial peritonitis in liver cirrhosis, and the use of stereotactic body radiation therapy in hepatocellular carcinoma. Clinicians and investigators who are interested in the management of chronic liver diseases will be acquainted with its merits and usefulness.

Chronic liver failure is a frequent condition in clinical practice that encompasses all manifestations of patients with end-stage liver diseases. Chronic liver failure is a multiorgan syndrome that affects the liver, kidneys, brain, heart, lungs, adrenal glands, and vascular, coagulation, and immune systems. Chronic Liver Failure: Mechanisms and Management covers for the first time all aspects of chronic liver failure in a single book, from pathogenesis to current management. Each chapter is written by a worldwide known expert in their area and all provide the latest state-of-the-art knowledge. This volume is specifically designed to provide answers to clinical questions to all doctors dealing with patients with liver diseases, not only clinical gastroenterologists and hepatologists, but also to internists, nephrologists, intensive care physicians, and transplant surgeons.