Aspects Of Neuroendocrinology

A panel of leading experts integrate the latest findings from basic and clinical science to create a comprehensive treatment of the processes by which the brain acts as an endocrine organ, not only to control hormonal functions, but also to maintain homeostasis and regulate behavior. The authors-recognized both as leaders in their fields and as skilled teachers-provide systematic coverage of the analytical, anatomical, functional, clinical, and pathological aspects of neuroendocrinology. Topics range from the interactions between the nervous and endocrine systems to the regulation of reproduction, development, metabolism, fluid balance, and biological rhythms. Neuroendocrinology in Physiology and Medicine offers an unprecedented marriage of clinical and basic knowledge that has been missing from classical neuroscience, endocrinology, and physiology texts. It will teach today's medical students and serve researchers as a valuable reference to this rapidly growing field.

Latest issue in the CURRENT TOPICS IN NEUROENDOCRINOLOGY se- ries which has been gaining a great deal of reputation as a primary source for reviews in neuroendocrinology and related areas in the past few years.

Neuroendocrinology, Volume II, is the second in a two-volume treatise designed to provide a survey of all aspects of the rapidly expanding science of neuroendocrinology. Only in recent years have the relations between the nervous system and the endocrine system come under intensive scrutiny, but their interactions have already been shown to be multiple and diverse. This diversity is reflected in the range of subjects covered. There are chapters on neural control of endocrine function; the effects of hormones on the brain; brain-endocrine interrelations during various phases of development; and the comparative aspects of neuroendocrine integration. The relation of brain chemistry to endocrine function, the effect of drugs on neuroendocrine mechanisms, and the new discipline of clinical neuroendocrinology have also been considered. Not only neurophysiologists and endocrinologists, but pharmacologists, zoologists, biochemists, psychologists, and those in clinical medicine will find the treatise of interest. Parts of neuroendocrinology have been discussed in other works, but this is the first treatise in which an attempt has been made to cover all ramifications of neuroendocrinology. This book can be used both as a text for advanced students and as a reference source.

Neuroendocrinology, Volume I, is the first in a two-volume treatise designed to provide a survey of all aspects of the rapidly expanding science of neuroendocrinology. Only in recent years have the relations between the nervous system and the endocrine system come under intensive scrutiny, but their interactions have already been shown to be multiple and diverse. This diversity is reflected in the range of subjects covered. There are chapters on neural control of endocrine function; the effects of hormones on the brain; brain-endocrine interrelations during various phases of development; and the comparative aspects of neuroendocrine integration. The relation of brain chemistry to endocrine function, the effect of drugs on neuroendocrine mechanisms, and the new discipline of clinical neuroendocrinology have also been considered. Not only neurophysiologists and endocrinologists, but pharmacologists, zoologists, biochemists, psychologists, and those in clinical medicine will find the treatise of interest. Parts of neuroendocrinology have been discussed in other works, but this is the first treatise in which an attempt has been made to cover all ramifications of neuroendocrinology. This book can be used both as a text for advanced students and as a reference source.

Der hiermit vorgelegte Band enthalt die Mehrzahl der Vortrage, die im August 1969 auf dem V.lnternationalen Symposium fiber Neurosekretion im Anato mischen Institut der Universitat Kiel unter reger internationaler Beteiligung gehalten wurden. Folgende Hauptthemen wurden behandelt: 1. Neurosecretion in invertebrates, 2. Adrenergic neurons, 3. Mechanisms of release of neurohypophyseal materials, 4. Hypothalamic control of anterior pituitary. Weitere Kurzvortrage waren verschiedenen Problemen der Neurosekretion gewidmet. Das Internationale Komitee fUr die Vorbereitung des Symposiums, dem auBer den Unterzeichneten die Herren Professoren H.S. HELLER (Bristol), G. STERBA (Leipzig) und FR. STUTINSKY (Strasbourg) angehorten, dankt dem Springer-Verlag fur die Sorgfalt, die er dieser Publikation wiederum angedeihen lieB, dem Kultus ministerium des Landes Schleswig-Holstein fur materielle Forderung des Sympo siums und Fraulein Dr. B. VON GAUD ECKER (Kiel) fur redaktionelle Unterstutzung. W. BARGMANN (Kiel) B. SCHARRER (New York) Contents BARGMANN, W.: Opening Remarks ... IX Neurosecretion in Invertebrates SCHARRER, B., and WEITZMAN, M.: Current Problems in Invertebrate Neurosecretion. ZIMMERMANN, P.: Neue Moglichkeiten zur f1uorescenzmikroskopischen Darstellung neu- sekretorischer Zellen ... 24 . NORMANN, T. CH.: The Mechanism of Hormone Release from Neurosecretory Axon Endings in the Calliphora erythrocephala ... 30 ... BONGA, S.E.W.: Investigations on Neurosecretion in the Central and Peripheral Nervous System of the Pulmonate Snail Lymmtea stagnalis (L.) ... 43 . NISHIOKA, R.S., BERN, H.A., and GOLDING, D.W.: Innervation of the Cephalopod Optic Gland ... 47 Adrenergic Neurons DAHLSTROM, A.: Adrenergic Neurons (With Special Reference to Fluorescence Microsco- cal Studies in Mammals) ... 55 ...

This book is designed as an introductory text in neuroendocrinology; the study of the interaction between the brain and endocrine system and the influence of this on behaviour. The endocrine glands, pituitary gland and hypothalamus and their interactions and hormones are discussed. The action of steroid and thyroid hormone receptors and the regulation of target cell response to hormones is examined. The function of neuropeptides is discussed with respect to the neuroendocrine system and behaviour. The neuroimmune system and lymphokines are described and the interaction between the neuroendocrine and neuroimmune systems discussed. Finally, methods for studying hormonal influences on behaviour are outlined. Each chapter has review and essay questions designed for advanced students and honours or graduate students with a background in neuroscience, respectively.