Assessing Genetic Risks
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Assessing Genetic Risks
Author | : Institute of Medicine,Committee on Assessing Genetic Risks |
Publsiher | : National Academies Press |
Total Pages | : 353 |
Release | : 1994-01-01 |
Genre | : Medical |
ISBN | : 9780309047982 |
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Raising hopes for disease treatment and prevention, but also the specter of discrimination and "designer genes," genetic testing is potentially one of the most socially explosive developments of our time. This book presents a current assessment of this rapidly evolving field, offering principles for actions and research and recommendations on key issues in genetic testing and screening. Advantages of early genetic knowledge are balanced with issues associated with such knowledge: availability of treatment, privacy and discrimination, personal decision-making, public health objectives, cost, and more. Among the important issues covered: Quality control in genetic testing. Appropriate roles for public agencies, private health practitioners, and laboratories. Value-neutral education and counseling for persons considering testing. Use of test results in insurance, employment, and other settings.
Assessing Genetic Risks
Author | : Institute of Medicine,Committee on Assessing Genetic Risks |
Publsiher | : National Academies Press |
Total Pages | : 353 |
Release | : 1994-02-01 |
Genre | : Medical |
ISBN | : 9780309086608 |
Download Assessing Genetic Risks Book in PDF, Epub and Kindle
Raising hopes for disease treatment and prevention, but also the specter of discrimination and "designer genes," genetic testing is potentially one of the most socially explosive developments of our time. This book presents a current assessment of this rapidly evolving field, offering principles for actions and research and recommendations on key issues in genetic testing and screening. Advantages of early genetic knowledge are balanced with issues associated with such knowledge: availability of treatment, privacy and discrimination, personal decision-making, public health objectives, cost, and more. Among the important issues covered: Quality control in genetic testing. Appropriate roles for public agencies, private health practitioners, and laboratories. Value-neutral education and counseling for persons considering testing. Use of test results in insurance, employment, and other settings.
Assessing Genetic Risks
Author | : Lori B. Andrews |
Publsiher | : Unknown |
Total Pages | : 0 |
Release | : 1994 |
Genre | : Medical |
ISBN | : 0585002177 |
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This book presents a current assessment of this rapidly evolving field, offering principles for actions and research and policy recommendations on key issues in genetic testing and screening. Among the important issues covered are quality control in genetic gesting; appropriate roles for public agencies, private health practitioners, research laboratories and centers, and companies involved in testing; value-neutral education and counseling for persons considering testing; use of test results in insurance, employment, and other settings; and more.
Assessing Genetic Risks
Author | : Anonim |
Publsiher | : Unknown |
Total Pages | : 28 |
Release | : 1993 |
Genre | : Human chromosome abnormalities |
ISBN | : OCLC:31283048 |
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An Evidence Framework for Genetic Testing
Author | : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Care Services,Board on the Health of Select Populations,Committee on the Evidence Base for Genetic Testing |
Publsiher | : National Academies Press |
Total Pages | : 149 |
Release | : 2017-04-21 |
Genre | : Medical |
ISBN | : 9780309453295 |
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Advances in genetics and genomics are transforming medical practice, resulting in a dramatic growth of genetic testing in the health care system. The rapid development of new technologies, however, has also brought challenges, including the need for rigorous evaluation of the validity and utility of genetic tests, questions regarding the best ways to incorporate them into medical practice, and how to weigh their cost against potential short- and long-term benefits. As the availability of genetic tests increases so do concerns about the achievement of meaningful improvements in clinical outcomes, costs of testing, and the potential for accentuating medical care inequality. Given the rapid pace in the development of genetic tests and new testing technologies, An Evidence Framework for Genetic Testing seeks to advance the development of an adequate evidence base for genetic tests to improve patient care and treatment. Additionally, this report recommends a framework for decision-making regarding the use of genetic tests in clinical care.
Understanding Genetics
Author | : Genetic Alliance,New York-Mid-Atlantic Consortium for Genetic and Newborn Screening Services |
Publsiher | : Lulu.com |
Total Pages | : 104 |
Release | : 2009 |
Genre | : Biology |
ISBN | : 9780982162217 |
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The purpose of this manual is to provide an educational genetics resource for individuals, families, and health professionals in the New York - Mid-Atlantic region and increase awareness of specialty care in genetics. The manual begins with a basic introduction to genetics concepts, followed by a description of the different types and applications of genetic tests. It also provides information about diagnosis of genetic disease, family history, newborn screening, and genetic counseling. Resources are included to assist in patient care, patient and professional education, and identification of specialty genetics services within the New York - Mid-Atlantic region. At the end of each section, a list of references is provided for additional information. Appendices can be copied for reference and offered to patients. These take-home resources are critical to helping both providers and patients understand some of the basic concepts and applications of genetics and genomics.
Genetic Toxicology and Cancer Risk Assessment
Author | : Wai Nang Choy |
Publsiher | : CRC Press |
Total Pages | : 405 |
Release | : 2001-08-31 |
Genre | : Medical |
ISBN | : 9780824745226 |
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Presents state-of-the-art regulatory cancer risk assessment models including a biologically based model for two-hit carcinogenesis and cell proliferation! This book comprehensively reviews the various roles of genetic toxicology in human cancer risk assessment conducted by United States and worldwide regulatory agencies-discussing hazard identification, dose-response relationships, exposure assessment, and current practices of risk characterization. Examines predictive values of mutagenicity tests, mechanisms of carcinogenesis, and conventional genotoxicity tests required by the International Conference on Harmonization and the Organization for Economic Cooperation and Development/Environmental Protection Agency guidelines! Comprised of contributions from prominent experts and risk assessors and including nearly 1200 references to facilitate further study, Genetic Toxicology and Cancer Risk Assessment reviews contemporary human cancer genetics as related to the mutagenic nature of carcinogenesis calculates acceptable exposure levels based on a carcinogenic threshold dose for nongenotoxic carcinogens reveals the rationale and methodology of quantitative estimation of human cancer risks using mathematical models discusses the threshold concept of carcinogenesis demonstrates how bacterial mutagenicity assays are the most reliable for predicting rodent carcinogens considers structural activity relationship (SAR) analysis of chemical carcinogenicity describes the emergence of the mouse lymphoma microwell and in vitro micronucleus assays illustrates the use of genetic biomarkers for dosimetry analysis and more! Linking human cancer genetics, mutagenicity assays, mechanisms of carcinogenesis, carcinogenic thresholds, molecular epidemiology, mathematical modeling, and quantitative cancer risk analysis, Genetic Toxicology and Cancer Risk Assessment is a must-have reference for toxicologists; oncologists; geneticists; biostatisticians; reproductive, developmental, cell, and molecular biologists; endocrinologists; biochemists; and upper-level undergraduate, graduate, and medical school students in these disciplines.
New Trends in Genetic Risk Assessment
Author | : Georges Jolles,A. Cordier |
Publsiher | : Unknown |
Total Pages | : 520 |
Release | : 1989 |
Genre | : Chemical mutagenesis |
ISBN | : UCAL:B4527245 |
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