Atlas Of Clear Cell Carcinoma Of The Ovary

Clear cell carcinoma (CCC) of the ovary with its unique clinical and biological features has attracted great attention, and calls for the publication of a specialized book on the subject. This is the first atlas that has narrowed its focus to CCC. Revealed here are the typical and variable histological features of CCC and related tumors. Hundreds of high-quality photographs help the reader to recognize the pathological features and clinical manifestations of CCC and to formulate diagnoses confidently and accurately. Data are based on the international central pathological review of the JGOG/GCIG3017 clinical trial in which experts around the world participated. Using a virtual slide system, interesting and significant features of CCC were discovered in the review of 652 cases. This book provides the newest information on the categorization and classification of CCC: growth patterns (papillary, tubocystic, solid, and adenofibromatous), cell types (classical hobnail and clear cell, eosinophilic, oxyphilic, and oncocytic), stromal changes (hyalinized, necrotic, hemorrhagic, lymphocytic infiltrative, luteinized, and psammomatous calcification), presence of endometriosis and atypical endometriosis, and borderline/atypical proliferative tumors. The Atlas of Clear Cell Carcinoma of the Ovary is an invaluable diagnostic resource for pathologists and gynecologic oncologists.

"Featuring more than 300 illustrations, the text covers pathology, biology, epidemiology, genetics, and screening through surgical management, the latest in chemotherapeutic regimens, and finally, palliative care"--P. [4] of cover.

Introducing the definitive gynecologic oncology reference and surgical atlas—in one essential text Gynecologic Oncology: Clinical Practice and Surgical Atlas brings together a skill-sharpening reference and full-color atlas to deliver an unmatched introduction to the field. As the most comprehensive, evidence-based gynecologic oncology resource available, this all-in-one resource offers high-yield coverage of the discipline’s underlying principles and proven management strategies. Each topic is written by experts and is presented in an easily accessible, consistent presentation that highlights clinical practice guidelines, along with the diagnosis and treatment of specific malignancies. This authoritative coverage is reinforced by the state-of-the-art surgical atlas, which offers a richly illustrated, overview of essential procedures designed to build your knowledge and confidence. FEATURES Consistent, streamlined presentation for each disease consists of: Epidemiology, Pathology, Clinical Presentation, Diagnosis, Staging, Treatment, Survival, Key management strategies Thorough examination of basic gynecological oncology topics, including epidemiology, clinical trial design, biostatistics, genetics and biology of gynecologic cancers, and diagnostic modalities Instructive, A-to-Z coverage of disease sites—from cervical cancer and gestational trophoblastic disease, to epithelial ovarian cancers and breast cancer—emphasizes evidence-based practice guidelines and critical supporting data In-depth, hands-on look at clinical management topics provides an up-to-date survey of perioperative and critical care; the principles of chemotherapy, radiation therapy, and immunotherapies; and quality of care and quality of life Full-color design filled with more than 600 figures, tables, algorithms, color photos, and illustrations Key points helpfully review the main topics to be covered in specific chapters, while chapter conclusions offer convenient summaries of each chapter’s core concepts Chapter-ending references underscore the book’s evidence-based approach

Although the histological typing of ovarian tumours is the focus of this volume, other aspects of investigation of a specimen of ovarian tumour are also important. Some of these aspects are mentioned in the text or illustrated. They include tumour grading, which is impor­ tantprognostically and therapeutically for certain types ofovarian tu­ mour, quantification ofcomponents in mixed tumours and evaluation of the stroma of certain tumours that are associated with endocrine function. Grading methodologies have varied from one tumour type to another and from one group of investigators to another for the same type of tumour. Because a standard internationally recognized grading methodology has not been established, no specific guidance is presented in this volume. Nevertheless, grading by any generally acceptable method should be incorporated in the diagnosis whenever appropriate. The clinical and pathological classification of the extent of tu­ mour growth (staging) should be taken into account for the purposes of treatment and prognosis. The TNlV1/FIGO system is therefore in­ cluded (p. 45). Histological Classification of Ovarian Tumours 1 Surface Epithelial-Stromal Tumours 1. 1 Serous tumours 1. 1. 1 Benign 1 1. 1. 1. 1 Cystadenoma 8441/0 Papillary cystadenoma 8460/0 1. 1. 1. 2 Surface papilloma . . . . . . . . . . . . . . . . . . . . . . . . 8461/0 1. 1. 1. 3 Adenofibroma; cystadenofibroma . . . . . 9014/0 1. 1. 2 Of borderline malignancy (of low malignant potential) 2 1. 1. 2. 1 Cystic tumour 8442/1 Papillary cystic tumour . . . . . . . . . . . . . . . . . . . . 846211 Surface papillary tumour. . . . . . . . . . . . . . . . . . . 8463/1 1. 1. 2. 2 1. 1. 2. 3 Adenofibroma; cystadenofibroma 9014/1 1. 1.