Atlas Of Diagnostically Challenging Melanocytic Neoplasms

This atlas provides a clear, concise overview of the most challenging circumstances faced by clinicians and pathologists when dealing with melanocytic neoplasms. The book is structured as a case series; for each case, the clinical and dermoscopic appearances are presented, accompanied by a brief but comprehensive description and compelling histopathologic images. When available, in vivo confocal microscopy images are also included to highlight additional diagnostic clues. Identification of key messages and selected references will further guide the reader in the diagnosis and management of the neoplasm under consideration. It is well known that melanocytic lesions can be difficult to interpret. Some lesions show an ambiguous combination of morphologic criteria, and in these cases interpretation entails a high degree of subjectivity that results in low interobserver agreement even among expert pathologists. This atlas demonstrates how the addition of clinical information, including that provided by dermoscopy, can assist in reaching a more confident diagnosis.

Melanocytic neoplasms are of capital importance for all surgical pathologists and dermatopathologists. These tumors span a huge range of morphologic expression and biologic behavior, are potentially of the highest medical significance and are often fraught with diagnostic pitfalls and high litigation risk. Pathology of Challenging Melanocytic Neoplasms offers a dynamic text where readers will encounter a broad spectrum of challenging melanocytic lesions, both benign and malignant and will thereby acquire a solid, working knowledge that they can immediately apply to daily diagnosis. The authors aim to clarify this often thorny field, keeping a steady focus on patient-related issues. The volume emphasizes the practical application of basic morphologic principles, immunohistochemistry and molecular methods in order to secure a confident diagnosis. Abundant illustrations display the characteristic features of the most important disease entities. Rather than being yet another encyclopedic work of reference, this volume takes a fresh approach as it resembles a series of stimulating seminars employing exemplary case material to highlight, illustrate, and succinctly discuss the key points. To this end, the reader will be guided through a series of paired cases that pose a significant diagnostic challenge. By comprehensively comparing and contrasting two related entities, each such chapter will illuminate an intellectual pathway through which an important diagnostic puzzle can be solved. To broaden the differential diagnosis even further, additional illustrative cases are added to each discussion. Algorithms and tables summarize key points. Clinically relevant, up-to-date references will be provided to guide further study. Written by experts in the field, this novel text will be of great value to surgical pathologists in practice and dermatologists as well as residents and fellows training in these specialties.

Diagnose any benign, premalignant, or malignant melanocytic lesion with over 1000 high-quality color images in this practical, easy-to-use reference. Drs. McKee and Calonje-editors of the best-selling dermatopathology reference Pathology of the Skin, 3rd Edition-present their expert knowledge by including diagnostic pearls and pitfalls throughout the text for quick, at-a-glance guidance. Correlate clinical and pathologic findings to produce a more accurate diagnosis from discussions of the clinical manifestations of melanocytic lesions. The format of the text makes this book an excellent resource for bench work and reviewing for exams. Expert Consult functionality allows you to access the entire contents of the book online, from any internet connection. Discusses the clinical manifestations of melanocytic lesions to help you correlate clinical and pathologic findings to produce a more accurate diagnosis. Functions as a unique and invaluable diagnostic resource with over 1,000 full-color photographs to provide you with a visual summary of all the features of melanocytic lesions encountered on a daily basis. Highlights the main pathologic criteria for all commonly seen melanocytic lesions in a concise, user-friendly format so that you get the information you need quickly for immediate problem-solving. Features "diagnostic pearls” and "pitfalls,” particularly emphasizing differential diagnosis, to help you avoid incorrect and inaccurate diagnoses. Presents the fully-searchable text online along with downloadable images for use in your electronic presentations.

Constituting a large percentage of everyday diagnostic practice, melanocytic pathology is a complex and challenging area with many difficult-to-diagnose lesions. This highly illustrated reference, written by three of the world’s leading dermatopathologists, provides authoritative guidance in the accurate diagnosis of even the most challenging pigmented skin tumors, helping you avoid pitfalls and recognize mimics. Covers nearly every variant of melanocytic tumors you’re likely to see. Emphasizes how to arrive at an efficient, accurate diagnosis, and includes dermoscopic findings for optimal diagnostic precision. Discusses modern analytic techniques (cytogenetics, molecular studies) and how to use them for diagnosis. Includes numerous case examples to illustrate the differential diagnoses and work-up; how to use ancillary techniques, along with their pros, cons, and limitations; and clinical follow-up. Presents the knowledge and experience of Klaus Busam, Pedram Gerami, and Richard Scolyer, – three dermatopathologists who are globally renowned for their expertise in melanoma pathology and analysis of melanocytic tumors by modern ancillary diagnostic techniques.

The interpretation of melanocytic tumors represents probably the most difficult task in the field of dermatopathology. The second edition of this text and atlas depicts a broad range of the most important and most challenging melanocytic lesions. Each individual case is illustrated with at least three high-quality color photographs and is commented on at length, highlighting the diagnostic clues. The goal of the authors is to assist the ordinary pathologist in making a precise workable diagnosis in their daily practice. They achieve this by providing simple criteria that will serve as a sound basis for an unequivocal diagnosis of either a benign or a malignant melanocytic neoplasm. The reader will find Histological Diagnosis of Nevi and Melanoma to be an invaluable guide to correct diagnosis even in difficult or rare cases.

As essential a text for GPs as for dermatologists, this book is an atlas-like representation of the various forms of melanocytic skin lesions associated with cutaneous melanomas and other pigmented skin tumors. It is a comprehensive and up-to-date text on the practical issues surrounding the management of individuals with these lesions. It encompasses the classical methods of morphology such as the clinical and dermoscopic examination and dermatopathology. The book also deals with the most up-to-date diagnostic approaches such as laser scanning in-vivo microscopy and automated diagnosis. The visual ‘atlas’ includes superb clinical, dermoscopic and histopathologic images.

Presents a comprehensive account of benign and malignant melanocytic lesions. It has become ever more apparent, especially with the recent advent of molecular classification, that melanoma is not one disease, and that prognosis in melanoma can vary considerably from lesions that present minimal risk, to dangerous malignancies at opposite ends of a spectrum. Highly illustrated, mainly in colour.