Basics Of Pet Imaging

This reference on the basics of PET and PET/CT imaging has been revised with concise chapters on PET fundamentals. The chapters include pertinent basic science plus equations along with sample problems and practice questions.

This book offers a wide-ranging and up-to-date overview of the basic science underlying PET and its preclinical and clinical applications in modern medicine. In addition, it provides the reader with a sound understanding of the scientific principles and use of PET in routine practice and biomedical imaging research. The opening sections address the fundamental physics, radiation safety, CT scanning dosimetry, and dosimetry of PET radiotracers, chemistry and regulation of PET radiopharmaceuticals, with information on labeling strategies, tracer quality control, and regulation of radiopharmaceutical production in Europe and the United States. PET physics and instrumentation are then discussed, covering the basic principles of PET and PET scanning systems, hybrid PET/CT and PET/MR imaging, system calibration, acceptance testing, and quality control. Subsequent sections focus on image reconstruction, processing, and quantitation in PET and hybrid PET and on imaging artifacts and correction techniques, with particular attention to partial volume correction and motion artifacts. The book closes by examining clinical applications of PET and hybrid PET and their physiological and/or molecular basis in conjunction with technical foundations in the disciplines of oncology, cardiology and neurology, PET in pediatric malignancy and its role in radiotherapy treatment planning. Basic Science of PET Imaging will meet the needs of nuclear medicine practitioners, other radiology specialists, and trainees in these fields.

This unparalleled text on the basics of PET imaging technology is an ideal resource for technologists and residents preparing for board examinations. Written by noted author Gopal B. Saha, Ph.D., the book also serves as a useful reference for practicing nuclear medicine professionals. Chapters are concise but comprehensive and emphasize the fundamentals, including physics, instrumentation and data acquisition, image reconstruction, production of PET radionuclides and radiopharmaceuticals, and regulatory and reimbursement issues. To maximize understanding, topics are complete with assessment questions, reviews of pertinent basic science, and lists of suggested reading. Helpful illustrations reinforce key concepts. A wealth of valuable data is presented in practical tables and appendixes as well. The remarkable combination of brevity and clarity of content makes it an ideal text and reference book for nuclear medicine professionals interested in basics of PET imaging.

Essential for students, science and medical graduates who want to understand the basic science of Positron Emission Tomography (PET), this book describes the physics, chemistry, technology and overview of the clinical uses behind the science of PET and the imaging techniques it uses. In recent years, PET has moved from high-end research imaging tool used by the highly specialized to an essential component of clinical evaluation in the clinic, especially in cancer management. Previously being the realm of scientists, this book explains PET instrumentation, radiochemistry, PET data acquisition and image formation, integration of structural and functional images, radiation dosimetry and protection, and applications in dedicated areas such as drug development, oncology, and gene expression imaging. The technologist, the science, engineering or chemistry graduate seeking further detailed information about PET, or the medical advanced trainee wishing to gain insight into the basic science of PET will find this book invaluable. This book is primarily repackaged content from the Basic Science section of the 'big' Valk book on PET. It contains new, completely revised and unchanged chapters covering the "basic sciences" section of the main book - total 18 chapters: 2 new (chapters 1, 16) 8 completely revised (chapters 4, 5, 8, 13, 14, 15, 17, 18) 3 minor corrections (chapters 2, 6, 11) 5 unchanged (chapters 3, 7, 9, 10, 12)

PET and SPECT are two of today’s most important medical-imaging methods, providing images that reveal subtle information about physiological processes in humans and animals. Emission Tomography: The Fundamentals of PET and SPECT explains the physics and engineering principles of these important functional-imaging methods. The technology of emission tomography is covered in detail, including historical origins, scientific and mathematical foundations, imaging systems and their components, image reconstruction and analysis, simulation techniques, and clinical and laboratory applications. The book describes the state of the art of emission tomography, including all facets of conventional SPECT and PET, as well as contemporary topics such as iterative image reconstruction, small-animal imaging, and PET/CT systems. This book is intended as a textbook and reference resource for graduate students, researchers, medical physicists, biomedical engineers, and professional engineers and physicists in the medical-imaging industry. Thorough tutorials of fundamental and advanced topics are presented by dozens of the leading researchers in PET and SPECT. SPECT has long been a mainstay of clinical imaging, and PET is now one of the world’s fastest growing medical imaging techniques, owing to its dramatic contributions to cancer imaging and other applications. Emission Tomography: The Fundamentals of PET and SPECT is an essential resource for understanding the technology of SPECT and PET, the most widely used forms of molecular imaging. *Contains thorough tutorial treatments, coupled with coverage of advanced topics *Three of the four holders of the prestigious Institute of Electrical and Electronics Engineers Medical Imaging Scientist Award are chapter contributors *Include color artwork

The aim of this book is to provide concise information and quick reference on the basics and practice of PET/CT for beginners. The chapters are written by Nuclear Medicine experts from different countries with enormous experience in PET/CT practice. Starting with the basics of PET/CT describing physics and the use of radiopharmaceuticals in PET/CT, the book explores the principle of PET/CT in radiotherapy planning. The last five chapters explore normal variation, pitfalls and artefacts commonly seen with various routinely used PET radiotracers. The text is enriched by tables and highlighted clinical cases for better understanding. This book will be of interest mostly to nuclear medicine physicians and radiologists, but it may be appealing also to a wider medical community including oncologists and radiotherapists.

The Third Edition of this classic text presents the basic concepts of PET imaging technology. Topics include basic physics of PET imaging; detectors, scanners and data collection; storage, display, and PACS; PET radionuclides and radiopharmaceuticals; reimbursement for PET procedures; and performance of PET studies. This revised edition is thoroughly updated and includes information on new PET scanning detectors and PET/MRI scanners; PET/MRI data acquisition; software packages; recently developed PET radiopharmaceuticals; and new procedures for PET studies. To maximize understanding, the book includes pertinent basic science principles, equations, sample problems and practice questions. Basics of PET Imaging, Third Edition, is an ideal resource for nuclear medicine physicians, residents and technologists.

In the fast-changing age of precision medicine, PET/CT is increasingly important for accurate cancer staging and evaluation of treatment response. Fundamentals of Oncologic PET/CT, by Dr. Gary A. Ulaner, offers an organized, systematic introduction to reading and interpreting PET/CT studies, ideal for radiology and nuclear medicine residents, practicing radiologists, medical oncologists, and radiation oncologists. Synthesizing eight years’ worth of cases and lectures from one of the largest cancer centers in the world, this title provides a real-world, practical approach, taking you through the body organ by organ as it explains how to integrate both the FDG PET and CT findings to best interpret each lesion.