Bio Carrier Vectors

This detailed book explores techniques used in research efforts to adopt and combine the best capabilities from natural and artificial vector systems to assemble improved delivery technologies aimed for specific applications. The collection discusses vectors other than the traditional viral and non-viral systems and explores ideas for blending the best features of bacteria, nanoparticles, peptides, and hybrid systems for the delivery of biomaterials into cells, as well as a chapter on the application of shotgun proteomics and mass spectrometry as a tool to analyze the proteomic profile changes in cells that result from these interventions. Written in the highly successful Methods in Molecular Biology format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Bio-Carrier Vectors: Methods and Protocols serves as an ideal guide for researchers working toward harnessing the power of multiple vectors in gene and drug delivery.

Here, front-line researchers in the booming field of nanobiotechnology describe the most promising approaches for bioinspired drug delivery, encompassing small molecule delivery, delivery of therapeutic proteins and gene delivery. The carriers surveyed include polymeric, proteinaceous and lipid systems on the nanoscale, with a focus on their adaptability for different cargoes and target tissues. Thanks to the broad coverage of carriers as well as cargoes discussed, every researcher in the field will find valuable information here.

A single tick bite can have debilitating consequences. Lyme disease is the most common disease carried by ticks in the United States, and the number of those afflicted is growing steadily. If left untreated, the diseases carried by ticks-known as tick-borne diseases-can cause severe pain, fatigue, neurological problems, and other serious health problems. The Institute of Medicine held a workshop October 11-12, 2010, to examine the state of the science in Lyme disease and other tick-borne diseases.

Biology is the study of life and living organisms. During the past some years, biology has shifted its focus from the structure of living organisms to looking more at how they work and function. These advances in biological knowledge raise new issues. The present book will help you to understand and in your own way contribute to the biological revolution which is taking place in our lives. This book has been revised and upgraded in accordance with the latest syllabus of Biology prescribed by the Council for Indian School Certificate Examinations, New Delhi. Unique features of this book are : • Written in a very simple, easy-to-understand language, and in a sequential manner. • Content is written in a comprehensive style with well-illustrated* properlylabelled diagrams. • Investigations (Experiments or Activities) related to the topics in each chapter have been given to cement the conceptual understanding. • Text and illustrations contribute to the basic understanding and appreciation of the field of biology. Charts and tables have been given to make the chapters more informative. • Some extra useful information has been provided within boxes to enhance the students' knowledge. • Comprehensive Self-check Questions (Test Yourself) to check the progress of the students and their retention capacity. • At the end of each chapter, Exercises have been given which comprise objective type questions, short answer type questions, long answer type questions and picture-based questions. • QR Codes have been provided at the end of each chapter to facilitate access to the Question Bank (Solved) of that chapter. • ICSE Specimen Question Paper (Solved). • Annual Examination Paper 2019 (Solved). • Five Model Test Papers (Unsolved), as per the latest specimen paper. I hope this book will prove very useful to the students and teachers. Suggestions and constructive criticism for the further improvement of the book would be gratefully acknowledged and incorporated in subsequent editions. -Author

This Dictionary provides an explanation of the main ideas of and concepts central to biology. Rather than offer an exhaustive list of technical terms, the author has selected a range of basic terms that are likely to meet the needs of most readers and librarians. The entries cover not only the traditional subject areas but also many of the topics that form the distinctive parts of human and social biology. Each entry in the Dictionary of Biology begins with a clear, one-sentence definition, followed by a further explanation, and, where appropriate, by specific examples. Numerical ideas are supported by working examples. Entries are cross-referenced, and the A-Z arrangement makes the book very easy to use.

This book discusses various fundamental aspects of polysaccharide based nano-biocarrier drug delivery systems and its application in the delivery of small molecules, proteins, peptides, oligonucleotides and genes. It also discusses advances in drug delivery systems in treatment of cancer, cardiovascular, pulmonary, and infectious diseases.

Focusing on three forms of biological threat--bioterrorism, biocrime and biohacking--the author examines the history of biowarfare and terrorism. Groups drawn to biological aggression are discussed, along with the array of viruses, bacteria and toxins they might use in their attacks. The phenomenon of biocrime--biological aggression targeting individuals for personal rather than ideological reasons--is explored, along with the growing trend of biohacking. Part II presents case studies of bioterrorism and biocrime from the United States and Japan.

Recent advances in stem cell biology, nanotechnology and gene therapy have opened new avenues for therapeutics. The availability of molecular therapeutics that rely on the delivery of DNA, RNA or proteins, harnessing enhanced delivery with nanoparticles, and the regenerative potential of stem cells (adult, embryonic or induced pluripotent stem cells) has had a tremendous impact on translational medicine. The chapters in this book cover a range of strategies for molecular and cellular therapies for human disease, their advantages, and central challenges to their widespread application. Potential solutions to these issues are also discussed in detail. Further, the book addresses numerous advances in the field of molecular therapeutics that will be of interest to the general scientific community. Lastly, the book provides specific examples of disease conditions for which these strategies have been transferred to the clinic. As such, it will be extremely useful for all students, researchers and clinicians working in the field of translational medicine and molecular therapeutics.