Bioactive Glasses

Bioactive Glasses: Materials, Properties and Applications, Second Edition provides revised, expanded and updated content on the current status of this unique material, including its properties, technologies and applications. The book is suitable for those active in the biomaterials and bioengineering field, and includes eight new chapters that cover material types, computational modeling, coatings and applications. Chapters deal with the materials and mechanical properties of bioactive glass and the applications of bioactive glasses, covering their uses in wound healing, maxillofacial surgery and bone tissue engineering, among other topics. With its distinguished editor and expert team of international contributors, the book is an invaluable reference for researchers and scientists in the field of biomaterials, both in academia and industry. Provides a detailed review of bioactive glasses, their properties, technologies and applications Comprehensively covers the materials and mechanical properties of bioactive glass and their further applications, including wound healing, maxillofacial surgery and bone tissue engineering Suitable for those active in the biomaterials and bioengineering field

The global ageing society has significantly increased the need for implant materials, which not only replace damaged or lost tissue but are also able to regenerate it. The field of bioactive glasses has been expanding continuously over recent years as they have been shown to bond with hard and soft tissue, release therapeutically active ions, and be capable of enhancing bone formation and regeneration. In addition, they are successfully being used to re-mineralise teeth, thereby making bioactive glasses highly attractive materials in both dentistry and medicine. Understanding the multidisciplinary requirements set by the human body’s environment and the special characteristics of the different families of bioactive glasses is a key in developing new compositions to novel clinical applications. Bioactive Glasses aims to bridge the different scientific communities associated with the field of bioactive glasses with focus on the materials science point of view. Emerging applications covered include soft tissue regeneration, wound healing, vascularisation, cancer treatment and drug delivery devices. This book provides a comprehensive overview of the latest applications of bioactive glasses for material scientists.

"More than 50 years have passed since Professor Larry L. Hench discovered Bioglass. However bioactive glasses still awake the fascination of scientists, lecturers, students, dentists, orthopedic surgeons, etc. all over the world. The research developed during the subsequent decades has resulted in new materials that significantly differ from the original melt-derived Bioglass. The use of the sol-gel process in the 1990's and the discovery of mesoporous bioactive glasses in the 2000's revealed new potential applications in the field of bone regeneration and drug delivery platforms. Besides, the development of rapid prototyping techniques has allowed manufacturing bioglass-based 3D scaffolds in combination with polymers, which boosts the long-standing expectative of using bioactive glasses for the treatment of critical bone defects. Finally, the advances in nanomedicine have opened new research lines involving the synthesis and development of bioactive glass nanoparticles. "Bioactive Glasses: Properties, Composition and Recent Applications" consists of ten chapters written by worldwide recognized experts in this field. The book covers the most important topics in the field of bioactive glasses, from its discovering to the most recent advances in preparation methods and applications. This book is addressed to researchers involved in the field of bioceramics, but it also an excellent tool for undergraduate and PhD students, given that nowadays Biomaterials Science is a subject included in the program of many universities. Only knowing the discoveries that fifty years ago fascinated us, our students will understand the current efforts to expand the applications of bioactive glasses"--

Biomedical, Therapeutic and Clinical Applications of Bioactive Glasses is an essential guide to bioactive glasses, offering an overview of all aspects of the development and utilization of this cutting-edge material. The book covers vital issues, including mesoporosity, encapsulation technologies, scaffold formation and coatings for a number of applications, including drug delivery, encapsulation, scaffolds and coatings. Readers will gain a strong understanding and practical knowledge of the therapeutic aspects of bioceramics, with a focus on glasses from a clinical point-of- view. Researchers, students and scientists involved in bioceramics, bone tissue engineering, regeneration and biomedical engineering will find this to be a comprehensive resource. Presents detailed coverage of bioactive glasses, including technologies and applications Includes all the major development areas related to bioactive glasses, enabling readers to understand the latest research Considers the potential future developments of bioactive glasses as a drug carrier

This new work is dedicated to glasses and their variants which can be used as biomaterials to repair diseased and damaged tissues. Bio-glasses are superior to other biomaterials in many applications, such as healing bone by signaling stem cells to become bone cells. Key features: First book on biomaterials to focus on bio-glasses Edited by a leading authority on bio-glasses trained by one of its inventors, Dr Larry Hench Supported by the International Commission on Glass (ICG) Authored by members of the ICG Biomedical Glass Committee, with the goal of creating a seamless textbook Written in an accessible style to facilitate rapid absorption of information Covers all types of glasses, their properties and applications, and demonstrates how glass is an attractive improvement to current procedures Of interest to the biomedical as well as the materials science community. The book covers all types of glasses: traditional glasses, bioactive glasses, sol-gel glasses, phosphate glasses, glass-ceramics, composites and hybrids. Alongside discussion on how bio-glasses are made, their properties, and the reasons for their use, the authors also cover their applications in dentistry, bone regeneration and tissue engineering and cancer treatment. Its solid guidance describes the steps needed to take a new material from concept to clinic, covering the essentials of patenting, scale-up, quality assurance and FDA approval.

This is the second edition of the classic book An Introduction to Bioceramics which provides a comprehensive overview of all types of ceramic and glass materials that are used in medicine and dentistry. The enormous growth of the field of bioceramics is due to the recognition by the medical and dental community of the importance of bioactive materials to stimulate repair and regeneration of tissues. This edition includes 21 new chapters that document the science and especially the clinical applications of the new generation of bioceramics in the field of tissue regeneration and repair. Important socioeconomic factors influencing the economics and availability of new medical treatments are covered with updates on regulatory procedures for new biomaterials, methods for technology transfer and ethical issues. The book contains 42 chapters that offer the only comprehensive treatment of the science, technology and clinical applications of all types of bioceramic materials used in medicine and dentistry. Each chapter is written by leaders in their specialized fields and is a thorough review of the subject matter, unlike many conference proceedings. All chapters have been edited to reflect the same writing style, making the book an easy read. The completeness of treatment of all types of bioceramics and their clinical applications makes the book unique in the field and invaluable to all readers.

This book describes the history, origin and basic characteristics of bioactive materials. It includes a chapter dedicated to hydroxyapatite mineral, its formation and its bioactive properties. The authors address how cytotoxicity is a determining step for bioactivity. Applications of bioactive materials in the contexts of tissue regeneration, bone regeneration and cancer therapy are also covered. Silicate, metallic and mesoporous glasses are described, as well as the challenges and future prospects of research in this field.

Bioactive Glasses and Glass-Ceramics Fundamentals and Applications A Comprehensive and Critical Overview of Bioactive Glasses and Glass-Ceramics Bioactive glasses and glass-ceramics are a versatile class of biocompatible materials that have an astonishing impact in biomedicine. Bioactive Glasses and Glass-Ceramics: Fundamentals and Applications presents topics on the functional properties, processing, and applications of bioactive glasses and glass-ceramics. The primary use of bioactive glasses and glass-ceramics is to repair bone and dental defects; however, their full potential is yet to be fulfilled. Many of today’s achievements in regenerative medicine and soft tissue healing were unthinkable when research began. As a result, the research involving bioactive glasses and glass-ceramics is highly stimulating and continuously progresses across many different disciplines including chemistry, materials science, bioengineering, biology, and medicine. Topics relating to these disciplines and covered within the work include: Fundamentals on bioactive glasses and glass-ceramics, bioactive glasses in today’s market, and improvements and challenges for the future Scalability and other issues when taking bioactive glass from lab to industry/commercialization applications, plus clinical challenges Trending topics such as bioactive glass porous scaffolds, additive manufacturing of bioactive glasses, and nano-engineering of bioactive glasses The various bioactive glass compositions which have been developed as medical products in an expanding range of forms and applications Bioactive Glasses and Glass-Ceramics: Fundamentals and Applications serves as a comprehensive and complete reference work on bioactive glasses and glass-ceramics for research and development (R&D) materials scientists, surgeons, and physicians, and leadership at glass and medical companies. Students and professors in fields of study pertaining to the aforementioned disciplines will also derive value from the work.