Biodiversity Natural Products And Cancer Treatment

This book is the first of its kind in bringing together biodiversity, chemical ecology, phytochemistry and cancer therapy. The highlight of the book is an exhaustive compilation of scientific data on biodiversity of medicinal plants, biodiversity and metagenomics, chemical ecology of medicinal plants, chemical ecology of marine organisms, natural products from terrestrial microbial organisms with activity towards cancer cells, marine organisms, ethnopharmacology and phytotherapy, contribution of African flora in world fight against cancer, natural products derived from terrestrial plants with activity towards cancer cells and established anticancer drugs from natural origin. The book discusses the state-of-the-art of each topic to serve as reference resource tools for graduate students as well as scientists and scholars in pharmaceutical sciences, pharmacology, organic chemistry and biochemistry, pharmacognosy, phytochemistry, ethnomedicine and ethnopharmacology, complementary and alternative medicine, medical and public health sciences and others. It includes cutting-edge developments in anticancer discovery from both medicinal plants and organisms. Contents:Biodiversity of Medicinal Plants (Kirsten Yacoub, Katharina Cibis and Corinna Risch)Biodiversity and Metagenomics (Eva-Maria Surmann and Thomas Efferth)Chemical Ecology of Medicinal Plants (Christian Kersten, Stephanie Lenz and Janina Wich)Chemical Ecology of Marine Organisms (André Antunes and Thomas Efferth)Natural Products from Terrestrial Microbial Organisms with Cytotoxic Cell Cycle Inhibitors (Theresa Dreis, Caroline Gartner, Julia Krebs and Mathias Schneider)Marine Compounds (Jennifer Honek and Thomas Efferth)Ethnopharmacology and Phytotherapy (Ariane Löhnert, Susanne Löhnert, Viktoriya Mogilevskaya and Sandra Schick)Contribution of African Flora in a Global Fight Against Cancer (Victor Kuete and Thomas Efferth)Natural Products Derived from Terrestrial Plants with Activity Towards Cancer Cells (Sonia Falenska, Ina Kirmes, Stephanie Kletting, Irini Karagianni and Karen Duffy)Established Anticancer Drugs from Natural Origin (Clara Becker, Kerstin Hoffmann, Laura Hoffmann, Tanya King, Franziska Faulstich, Katrin Viertel, Victor Kuete and Thomas Efferth) Readership: Graduate students and scientists in pharmaceutical sciences, pharmacology, organic chemistry, biochemistry, pharmacognosy, phytochemistry, ethnomedicine & ethnopharmacology, compementary & alternative medicine, public health. Key Features:This book is the first of its kind bringing together biodiversity, chemical ecology, phytochemistry and cancer therapyThe book provides the state-of-the-art in anticancer discovery from medicinal plantsThe book also provides the state-of-the-art in anticancer discovery from marine organismsKeywords:Biodiversity;Cancer;Marine Products;Natural Products;Established Drugs

Biodiversity and Biomedicine: Our Future provides a new outlook on Earth's animal, plant, and fungi species as vital sources for human health treatments. While there are over 10 million various species on the planet, only 2 million have been discovered and named. This book identifies modern ways to incorporate Earth's species into biomedical practices and emphasizes the need for biodiversity conservation. Written by leading biodiversity and biomedical experts, the book begins with new insights on the benefits of biologically active compounds found in fungi and plants, including a chapter on the use of wild fruits as a treatment option. The book goes on to discuss the roles of animals, such as amphibians and reptiles, and how the threatened presence of these species must be reversed to conserve biodiversity. It also discusses marine organisms, including plants, animals, and microbes, as essential in contributing to human health. Biodiversity and Biomedicine: Our Future is a vital source for researchers and practitioners specializing in biodiversity and conservation studies. Students in natural medicine and biological conservation will also find this useful to learn of the world's most bio-rich communities and the molecular diversity of various species. Presents new developments in documenting and identifying species for biodiversity conservation and ethical considerations for biodiversity research Examines biodiversity as an irreplaceable resource for biomedical breakthroughs using available species for medical research Discusses challenges and opportunities for biodiversity protection and research in biosphere reserves

Evolutionary Diversity as a Source for Anticancer Molecules discusses evolutionary diversity as source for anticancer agents derived from bacteria, algae, bryophytes, pteridophytes, and gymnosperms. The book goes over the isolation of anticancer agents and the technologyenabled screening process used to develop anticancer drugs. The book also includes discussion of the nutraceuticals and natural productsderived from invertebrates that can be used as part of cancer treatment. Evolutionary Diversity as a Source for Anticancer Molecules also deals with some of the current challenges in the prevention of cancer as well as the side effects of conventional drugs used for cancer patients.This book is a valuable resource for cancer researchers, oncologists, biotechnologists, pharmacologists, and any member of the biomedicalfield interested in understanding more about natural products with anticancer potential. Discusses the application of natural products in place of conventional drugs to minimize the side effects in cancer treatment Explains the relation between evolutionary mechanisms and climate change for production of secondary metabolites

Western drugs and target medicines for disease treatment come with undesirable side effects that have limited their use in patients for an extended period of time. It is warranted to develop a treatment strategy with alternative medicines to reduce toxicity relating to drugs, in particular, cancer drugs. Thus, a combination therapy with herbal medicines provides a more effective treatment method for hard-to-treat diseases. The recent breakthroughs in naturally occurring small molecules from herbal medicines have provided experimental evidence and are clinically significant in treatment strategies.This unique volume presents the recent developments in the field of herbal medicines for the treatment of diseases and cancer. Recent progress on small molecules isolated from herbal medicines that exhibit therapeutic benefits in humans is highlighted. The book provides an overview of the significant discoveries and pioneering contributions of herbal medicines in combination with other drugs; the author's evaluation of the combination therapy in cancer treatment; and a recent discovery of crocodile tissue extract with pharmacological properties.

This volume provides summarized scientific evidence of the different classes of plant-derived phytocompounds, their sources, chemical structures, anticancer properties, mechanisms of action, methods of extraction, and their applications in cancer therapy. It also discusses endophyte-derived compounds as chemopreventives to treat various cancer types. In addition, it provides detailed information on the enhanced production of therapeutically valuable anticancer metabolites using biotechnological interventions such as plant cell and tissue culture approaches, including in vitro-, hairy root- and cell-suspension culture; and metabolic engineering of biosynthetic pathways. Anticancer Plants: Natural Products and Biotechnological Implements – Volume 2” explores the natural bioactive compounds isolated from plants as well as fungal endophytes, their chemistry, and preventive effects to reduce the risk of cancer. Moreover, it highlights the genomics/proteomics approaches and biotechnological implementations. Providing solutions to deal with the challenges involved in cancer therapy, the book benefits a wide range of readers including academics, students, and industrial experts working in the area of natural products, medicinal plant chemistry, pharmacology, and biotechnology.

Exploring the interconnectedness of human health, biodiversity, and bioethics. We all depend on environmental biodiversity for clean air, safe water, adequate nutrition, effective drugs, and protection from infectious diseases. Today's healthcare experts and policymakers are keenly aware that biodiversity is one of the crucial determinants of health—not only for individuals but also for the human population of the planet. Unfortunately, rapid globalization and ongoing environmental degradation mean that biodiversity is rapidly deteriorating, threatening planetary health on a mass scale. In Wounded Planet, Henk A.M.J. ten Have argues that the ethical debate about healthcare has become too narrow and individualized. We must, he writes, adopt a new bioethical discourse—one that deals with issues of justice, equality, vulnerability, human rights, and solidarity—in order to adequately reflect the serious threat that current loss of biodiversity poses to planetary health. Exploring modern environmental challenges in depth, ten Have persuasively demonstrates that environmental concerns can no longer be separated from healthcare challenges, and thus should be included in global bioethics. Going beyond an individualized perspective, he poses audacious questions: What does it mean that patients are poor or uninsured and cannot afford suggested medicines? How can we deal with the air and water pollution that are producing a patient's illness? How do we respond to patients complaining about the safety and quality of drinking water in their neighborhood? Touching on infectious and noncommunicable diseases, as well as food, medicine, and water, Wounded Planet transcends the limited vision of mainstream bioethics to compassionately reveal how healthcare and medicine must take a broad perspective that includes the social and environmental conditions in which individuals live.

Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up exciting new opportunities in the field of new drug development to the pharmaceutical industry. The series also covers the synthesis or testing and recording of the medicinal properties of natural products. Describes the chemistry of bioactive natural products Contains contributions by leading authorities in the field A valuable resource for natural products and medicinal chemistry

Plants, marine organisms, and microorganisms have evolved complex chemical defense and signaling systems that are designed to protect them from predators and provide other biological benefits. These organisms thus produce substances containing novel chemotypes that may have beneficial effects for humans. As collection methods improve and new screen