Biology And Ecology Of Pharmaceutical Marine Tunicates

The ocean is a source of unique natural products, mainly accumulated in living organisms. The c.4000 species of tunicates or sea squirts (Phylum, Chordata; Subphylum, Urochordata) are a high-potential yet under-studied source of bioactive compounds for pharmaceuticals. The secondary metabolites such as alkaloids isolated from these organisms have led to the discovery of an approved anti-tumor drug, anti-cancer drugs Yondelis® and Aplidin®, as well as many others in clinical trial. There is an urgent need for more research on the bioactive compounds of marine tunicates and better knowledge about the identification and biology of these species. This is the first focused book to meet this need. The taxonomy, common name, global distribution, habitat, diagnostic features and pharmaceutical compounds (along with their activities) of 165 key species of tunicates are given, with high-quality illustrations. Contributed by scientists of both Marine Biology and Pharmacy disciplines, this book will serve as a standard reference for researchers, teachers and students of Fisheries Science, Marine Biology, Life Sciences, Biotechnology, Natural Products, and Pharmacy, and as a valuable guide for pharmaceutical companies involved in the development of new drugs from marine organisms.

Biology and Ecology of Pharmaceutical Marine Molluscs is the first comprehensive book of its kind written by scientists from both the Marine Biology and Pharmacy disciplines to fill the long-felt need for a marine natural products book devoted exclusively to molluscs. The taxonomy, common name, global distribution, habitat, diagnostic features and pharmaceutical compounds (along with their activities) of 275 species of marine molluscs are given in this comprehensive work, with accompanying illustrations. Bioactive substances isolated from marine invertebrates such as poriferans, coelenterates, molluscs, echinoderms, bryozoans and tunicates have been reported to possess antiviral, antimicrobial, antiprotozoal, antifungal, antihelmintic and anticancer activities. Among the marine invertebrates, marine molluscs have significant commercial applications; for instance, as a source of food, ornaments and production of lime. A few species of molluscs have also been reported to act as scavengers in cleaning the environment and pollution indicators. Recently, many molluscan species have been identified as a potential source of secondary metabolites, having a wide range of pharmaceutical applications. This should be a standard reference for students, researchers and teachers of disciplines such as Pharmacy, Fisheries Science, Marine Biology, Life Sciences, Biotechnology and Biochemistry, as well as a valuable guide for pharmaceutical companies involved in the development of new drugs from marine molluscs.

The first comprehensive book on the biology and ecology of pharmaceutical echinoderms. Contributed by scientists of both marine biology and pharmacy disciplines. All reported echinoderm species producing secondary metabolites are dealt with. Having previously only been known as nutritional invertebrates, a book exploring the contribution of the echinoderms as sources of secondary metabolites for therapeutic compounds is timely. All 200+ images are produced in full color, providing a high-quality reference. This book provides the taxonomy, common name, global distribution, habitat, diagnostic features and pharmaceutical compounds (along with their activities) of 150 species of echinoderms along with over 200 detailed illustrations in glorious color. Among the biota of marine habitats, the echinoderms include sea cucumbers, starfish, sea urchins and sand dollars, crinoids and sea lillies, brittle stars and basket stars. Their importance as a promising source of bioactive compounds for development of pharmaceuticals and potential therapeutic applications has been growing rapidly, showing extensive application in the treatment of many diseases. starfish, sea urchins and sand dollars, crinoids and sea lillies, brittle stars and basket stars. Their importance as a promising source of bioactive compounds for development of pharmaceuticals and potential therapeutic applications has been growing rapidly, showing extensive application in the treatment of many diseases.

The first comprehensive book on the biology and ecology of pharmaceutical cnidarians, answering a need for more knowledge about the identification, biology, natural products and bioactivities of these living resources. Contributed by scientists of both marine biology and pharmacy disciplines. Identifies the correct marine species, shows the ecological parameters of that species, and explores its biological values with particular attention to primary and secondary metabolites or bioactive constituents. A useful supplementary text on Marine Biology and Pharmacology courses. Nearly 200 illustrations are produced in full color, providing a high-quality reference. This book provides the taxonomy, common name, global distribution, habitat, diagnostic features, and pharmaceutical compounds (along with their activities) of 200 species of marine cnidarians along with nearly 200 detailed illustrations in glorious color. The phylum Cnidaria (formerly Coelenterata) is a large, diverse, and ecologically important group of marine invertebrates which make up 40 percent of the biomass of the oceans. Marine invertebrates are the richest source of marine natural products with potential applications in the pharmaceutical and medical sectors, and it has been reported that over 3000 bioactive compounds have been described from this phylum alone, mostly in the last decade.

Key features: A standard reference for researchers, teachers and students of Marine Biology, Fisheries Science, Botany/Plant Science, Biotechnology, Natural Products, and Pharmacy, their libraries A valuable guide for pharmaceutical companies involved in the development of new drugs from marine plants Presents the taxonomy, common name, global distribution, and habitat of 400 species of marine plants Provides the diagnostic features and pharmaceutical compounds (along with their chemical structure and activities) of 400 species of marine plants Includes more than 600 detailed illustrations Covers blue-green algae, green algae, brown algae, and red algae Marine plants such as algae (blue-green algae and seaweeds), seagrasses, mangrove plants, salt-tolerant or salt-loving plants (halophytes) and coastal sand dune plants are known to generate approximately 70% of oxygen on earth, and help regulate oxygen in the atmosphere. These plants are potential sources of nutrients and are also considered valuable for the development of new drugs owing to their unique bioactive compounds. This book provides the taxonomy, common name, global distribution, habitat, diagnostic features and pharmaceutical compounds (along with their activities) of 400 species of marine plants, accompanied by high quality illustrations. Biology and Ecology of Pharmaceutical Marine Plants is the first comprehensive book of its kind written by scientists from both the Marine Biology and Pharmacy disciplines to fill the long-felt need for a marine natural products book devoted exclusively to plants. It should be a standard reference for students, researchers and teachers of disciplines such as Pharmacy, Fisheries Science, Marine Biology, Life Sciences, Biotechnology and Biochemistry, as well as a valuable guide for pharmaceutical companies involved in the development of new drugs from marine plants.

Key features: Serves as a standard reference for researchers, teachers and students of various disciplines such as Fisheries Science, Marine Biology, Life Sciences, Biotechnology, Natural Products, and Pharmacy, their libraries, and as a valuable guide for pharmaceutical companies involved in the development of new drugs from marine sponges Presents the taxonomy, common name, global distribution, and habitat of 250 species of marine sponges Provides the diagnostic features and pharmaceutical compounds (along with their chemical structure and activities) of 450 species of marine sponges Includes more than 500 detailed illustrations Biology and Ecology of Pharmaceutical Marine Spongesis the first comprehensive book of its kind written by scientists from both the Marine Biology and Pharmacy disciplines to fill the long-felt need for a marine natural products book devoted exclusively to sponges. Sponges are the most primitive multicelled animals that have existed for 700 - 800 million years. Despite their wide range of functional roles, not much is known about them. Marine sponges are responsible for more than 5,300 pharmaceutical products and some species have the potential to provide future drugs to prevent and treat important medical conditions such as cancer, a range of viral diseases, malaria, and inflammatory diseases. Nucleosides derived from sponges were the basis for the synthesis of Ara-C, the first marine-derived anticancer agent, currently used in the routine treatment of patients with leukemia and lymphoma. Marine sponges are the potential sources of many unique metabolites with anticancer,anti-inflammatory, antibiotic, antiviral, antimalarial, and immune or neurosuppressive properties. Although many bioactives have been discovered in marine sponges, only a few of these compounds have been commercialized. This book hopes to change that, providing the taxonomy, common name, global distribution, habitat, diagnostic features and pharmaceutical compounds (along with their chemical structure and activities) of 450 species of marine sponges, accompanied by high-quality illustrations. The book should be a standard reference for students, researchers and teachers of disciplines such as Fisheries Science, Marine Biology, Biochemistry, Biotechnology and Pharmacy and a valuable guide for pharmaceutical companies involved in the development of new drugs from marine sponges.

Advances in Marine Biology has been providing in-depth and up-to-date reviews on all aspects of marine biology since 1963--over 40 years of outstanding coverage! The series is well known for its excellent reviews and editing. Now edited by Michael Lesser (University of New Hampshire, USA) with an internationally renowned Editorial Board, the serial publishes in-depth and up-to-date content on many topics that will appeal to postgraduates and researchers in marine biology, fisheries science, ecology, zoology, and biological oceanography. Volumes cover all areas of marine science, both applied and basic, a wide range of topical areas from all areas of marine ecology, oceanography, fisheries management and molecular biology and the full range of geographic areas from polar seas to tropical coral reefs. AMB volumes solicit and publish review articles on the latest advances in marine biology Many of the authors of these review articles are the leading figures in their field of study and the material is widely used by managers, students and academic professionals in the marine sciences