Biopolymers In Drug Delivery And Regenerative Medicine

Biopolymers including natural (e.g., polysaccharides, proteins, gums, natural rubbers, bacterial polymers), synthetic (e.g., aliphatic polyesters and polyphosphoester), and biocomposites are of paramount interest in regenerative medicine, due to their availability, processability, and low toxicity. Moreover, the structuration of biopolymer-based materials at the nano- and microscale along with their chemical properties are crucial in the engineering of advanced carriers for drug products. Finally, combination products including or based on biopolymers for controlled drug release offer a powerful solution to improve the tissue integration and biological response of these materials. Understanding the drug delivery mechanisms, efficiency, and toxicity of such systems may be useful for regenerative medicine and pharmaceutical technology.

Natural Biopolymers in Drug Delivery and Tissue Engineering systematically examines a broad range of natural polymers and their applications in drug delivery and tissue engineering. The book thoroughly collates the most relevant and up-to-date research on natural biopolymers, covering a variety of key natural polymer types such as chitin, chitosan, alginate, guar gum and collagen. It is divided into two sections, covering drug delivery and tissue engineering applications. Each section focuses on natural biopolymers in the form of scaffolds, membranes, films, gels and nanoparticles, thus helping the reader select not only the most appropriate polymer type, but also the most relevant structure. This comprehensive resource is ideal for materials scientists, biomedical engineers, tissue engineers, pharmaceutical scientists and anyone interested in developing novel materials for biomedical applications. Covers both drug delivery and tissue engineering applications of natural biopolymers, helping bridge the gap between the two Details a range of natural polymer types, ensuring all relevant options are presented Discusses the benefits, challenges and clinical translation of natural biopolymers

This book presents an experimental and computational account of the applications of biopolymers in the field of medicine. Biopolymers are macromolecules produced by living systems, such as proteins, polypeptides, nucleic acids, and polysaccharides. Their advantages over polymers produced using synthetic chemistry include: diversity, abundance, relatively low cost, and sustainability. This book explains techniques for the production of different biodevices, such as scaffolds, hydrogels, functional nanoparticles, microcapsules, and nanocapsules. Furthermore, developments in nanodrug delivery, gene therapy, and tissue engineering are described.

Provides insight into biopolymers, their physicochemical properties, and their biomedical and biotechnological applications This comprehensive book is a one-stop reference for the production, modifications, and assessment of biopolymers. It highlights the technical and methodological advancements in introducing biopolymers, their study, and promoted applications. "Biopolymers for Biomedical and Biotechnological Applications" begins with a general overview of biopolymers, properties, and biocompatibility. It then provides in-depth information in three dedicated sections: Biopolymers through Bioengineering and Biotechnology Venues; Polymeric Biomaterials with Wide Applications; and Biopolymers for Specific Applications. Chapters cover: advances in biocompatibility; advanced microbial polysaccharides; microbial cell factories for biomanufacturing of polysaccharides; exploitation of exopolysaccharides from lactic acid bacteria; and the new biopolymer for biomedical application called nanocellulose. Advances in mucin biopolymer research are presented, along with those in the synthesis of fibrous proteins and their applications. The book looks at microbial polyhydroxyalkanoates (PHAs), as well as natural and synthetic biopolymers in drug delivery and tissue engineering. It finishes with a chapter on the current state and applications of, and future trends in, biopolymers in regenerative medicine. * Offers a complete and thorough treatment of biopolymers from synthesis strategies and physiochemical properties to applications in industrial and medical biotechnology * Discusses the most attracted biopolymers with wide and specific applications * Takes a systematic approach to the field which allows readers to grasp and implement strategies for biomedical and biotechnological applications "Biopolymers for Biomedical and Biotechnological Applications" appeals to biotechnologists, bioengineers, and polymer chemists, as well as to those working in the biotechnological industry and institutes.

"This Ebook describes the applicability of diverse natural and synthetic biopolymers and their blends in drugs, vaccines and gene delivery. It would serve as a concise body of information on biopolymers for researchers, industries and students of pharmaceu"

Plant and Algal Hydrogels for Drug Delivery and Regenerative Medicine offers a materials-focused and systematic overview of biopolymeric hydrogels utilized for biomedical applications. The book details the synthesis and characterization of plant and algal-based hydrogels, with each chapter addressing a separate polysaccharide hydrogel type. Specific applications in drug delivery and regenerative medicine are also discussed, highlighting the efficacy, biocompatibility, benefits and challenges for each polysaccharide hydrogel subtype. There is increasing demand for biomaterials which reduce/prevent the host response, inflammation and rejection, hence this book provides a timely resource. Biopolymeric hydrogels have skyrocketed because of their necessity in in vivo applications. They create an environment similar to living tissue, which is both biocompatible and biodegradable. Plant and algal polysaccharides in particular are well-equipped with functional groups that are easily modified for beneficial results. Systematically covers each plant and algal polysaccharide hydrogel subtype, from starch-based hydrogels to pectin and alginate-based hydrogels Provides an end-to-end description of the synthesis, characterization and application of biopolymeric hydrogels for drug delivery and regenerative medicine Appeals to a diverse readership, including those in biomedicine, pharmacy, polymer chemistry, biochemistry, materials science, biomedical engineering, and other biotechnology related disciplines

Biopolymer-Based Composites: Drug Delivery and Biomedical Applications presents a comprehensive review on recent developments in biopolymer-based composites and their use in drug delivery and biomedical applications. The information contained in this book is critical for the more efficient use of composites, as detailed up-to-date information is a pre-requirement. The information provided brings cutting-edge developments to the attention of young investigators to encourage further advances in the field of bio-composite research. Currently, biopolymers are being investigated for the design of various drug delivery and biomedical devices due to their non-toxic, biodegradable and biocompatible nature. Mostly, biopolymer-based solid orals, gels, hydrogel beads, and transdermal matrices have been designed in order to control drug/protein release in simulated bio-fluids. Presents the most updated information in the field of pharmaceutical and biological sciences Contains color figures and illustrations to help users understand key topics Useful guide for young researchers working towards new innovations Includes chapters covered by eminent scientists in the field

Biopolymers including natural (e.g., polysaccharides, proteins, gums, natural rubbers, bacterial polymers), synthetic (e.g., aliphatic polyesters and polyphosphoester), and biocomposites are of paramount interest in regenerative medicine, due to their availability, processability, and low toxicity. Moreover, the structuration of biopolymer-based materials at the nano- and microscale along with their chemical properties are crucial in the engineering of advanced carriers for drug products. Finally, combination products including or based on biopolymers for controlled drug release offer a powerful solution to improve the tissue integration and biological response of these materials. Understanding the drug delivery mechanisms, efficiency, and toxicity of such systems may be useful for regenerative medicine and pharmaceutical technology. The main aim of the Special Issue on “Biopolymers in Drug Delivery and Regenerative Medicine” is to gather recent findings and current advances on biopolymer research for biomedical applications, particularly in regenerative medicine, wound healing, and drug delivery. Contributions to this issue can be as original research or review articles and may cover all aspects of biopolymer research, ranging from the chemical synthesis and characterization of modified biopolymers, their processing in different morphologies and hierarchical structures, as well as their assessment for biomedical uses.