Biosensors Recent Advances And Future Challenges

The present book is devoted to all aspects of biosensing in a very broad definition, including, but not limited to, biomolecular composition used in biosensors (e.g., biocatalytic enzymes, DNAzymes, abiotic nanospecies with biocatalytic features, bioreceptors, DNA/RNA, aptasensors, etc.), physical signal transduction mechanisms (e.g., electrochemical, optical, magnetic, etc.), engineering of different biosensing platforms, operation of biosensors in vitro and in vivo (implantable or wearable devices), self-powered biosensors, etc. The biosensors can be represented with analogue devices measuring concentrations of analytes and binary devices operating in the YES/NO format, possibly with logical processing of input signals. Furthermore, the book is aimed at attracting young scientists and introducing them to the field, while providing newcomers with an enormous collection of literature references.

The present book is devoted to all aspects of biosensing in a very broad definition, including, but not limited to, biomolecular composition used in biosensors (e.g., biocatalytic enzymes, DNAzymes, abiotic nanospecies with biocatalytic features, bioreceptors, DNA/RNA, aptasensors, etc.), physical signal transduction mechanisms (e.g., electrochemical, optical, magnetic, etc.), engineering of different biosensing platforms, operation of biosensors in vitro and in vivo (implantable or wearable devices), self-powered biosensors, etc. The biosensors can be represented with analogue devices measuring concentrations of analytes and binary devices operating in the YES/NO format, possibly with logical processing of input signals. Furthermore, the book is aimed at attracting young scientists and introducing them to the field, while providing newcomers with an enormous collection of literature references.

Many researchers and research groups around the globe are dealing with interdisciplinary problems and multidisciplinary groups; but especially those that deal everyday with biosensors have the feeling of not having enough personnel with the sufficient background to cover all topics. With this feeling in our minds, we decided to invite wonderful researchers from different parts to design this book, not as a conventional biosensor’s book, but as an interesting journey in the complex world of biosensors. A close look to some recent and key advances on the topic, but at the same time tips through novel mathematical modelling to improve our work, and last but not least, tricks to fool those undesired electrical disturbances that commonly messes our daily work can be found in these pages. Feel free to navigate the book through its chapters, once in your hands you will feel eager to learn more about biosensors. It has been an experience to put all this together; but now, with the book ready, we can say that this trip has being a wonderful adventure. That is why want to thank all the authors for their great contributions, the Editorial and Irene for their constant input, and to you, the reader, for being part of this book.

This book entails detailed information on the utilization of nanobiosensor as an effective technology for the effective detection, monitoring, and management of environmental contaminations to ensure its sustainability and humanity's well-being. The higher level of anthropogenic action has been identified as a threat to humankind's existence due to the higher level of xenobiotic and toxic substances that could interrupt the normal ecosystem. This has prompted numerous agencies both locally and internationally that could play a significant role in environmental pollution mitigation. The application of nanobiosensor has been identified as a sustainable technique that could be applied to ensure proper detection and identification of several environmental contaminants. Nanomaterial’s possible applications created an innovative domain called nanomaterials based biosensors machinery as one of nanotechnology's ultimate sub-divisions. The application of nanomaterials based biosensors machinery and their advancements could be applied globally to resolve numerous environmental sectors' challenges to guarantee the environment's quality and safety. The book will be an excellent collection of reviews based on contemporary research and developments on nanomaterials utilization and applications in environmental monitoring along with their prospects. The book will attempt to give a comprehensive idea of nanomaterial concepts for nanobiosensors applications in an environmental context to help students, researchers, and professionals/practitioners recognize nanomaterials' significance in the environmental domain. The book will also help understand and address the environmental sectors' complications via nanomaterials' utilization and applications. Hence, this book will serve as a textbook and will help students, professionals/practitioners, scientists, researchers, and academicians in various research domains.

Advanced Biosensors for Health Care Applications highlights the different types of prognostic and diagnostic biomarkers associated with cancer, diabetes, Alzheimer's disease, brain and retinal diseases, cardiovascular diseases, bacterial infections, as well as various types of electrochemical biosensor techniques used for early detection of the potential biomarkers of these diseases. Many advanced nanomaterials have attracted intense interests with their unique optical and electrical properties, high stability, and good biocompatibility. Based on these properties, advanced nanoparticles have been used as biomolecular carriers, signal producers, and signal amplifiers in biosensor design. Recent studies reported that there are several diagnostic methods available, but the major issue is the sensitivity and selectivity of these approaches. This book outlines the need of novel strategies for developing new systems to retrieve health information of patients in real time. It explores the potential of nano-multidisciplinary science in the design and development of smart sensing technology using micro-nanoelectrodes, novel sensing materials, integration with MEMS, miniaturized transduction systems, novel sensing strategy, that is, FET, CMOS, System-on-a-Chip (SoC), Diagnostic-on-a-Chip (DoC), and Lab-on-a-Chip (LOC), for diagnostics and personalized health-care monitoring. It is a useful handbook for specialists in biotechnology and biochemical engineering. Describes advanced nanomaterials for biosensor applications Relates the properties of available nanomaterials to specific biomarkers applications Includes diagnosis and electrochemical studies based on biosensors Explores the potential of nano-multidisciplinary science to design and develop smart sensing technologies Describes novel strategies for developing a new class of assay systems to retrieve the desired health information

Point-of-Care Biosensors for Infectious Diseases Comprehensive resource covering key developments in biosensor-based diagnostics for infectious diseases With its overview of currently available technologies, Point-of-Care Biosensors for Infectious Diseases serves as a starting point for the successful development and application of pathogen biosensors in a point-of-care setting. Here, expert authors review current challenges in pathogen detection and the selection of suitable biomarkers, detail currently available biosensor platforms including electrochemical, piezoelectric, magnetic, and optical sensors, and cover technology development for point-of-care biosensors for viral, bacterial, and parasitic infections. Point-of-Care Biosensors for Infectious Diseases covers key topics such as: Fundamentals of biosensor detection, with a focus on optical and electrochemical techniques Organic and inorganic based nanomaterials for healthcare diagnostics Strategies for miniaturizing biosensor devices, and state-of-the-art integrated sensing platforms Latest trends in point-of-care biosensing systems to detect, diagnose, and monitor infectious diseases Providing comprehensive coverage of the subject, Point-of-Care Biosensors for Infectious Diseases is an excellent reference for all developers, researchers, and technology managers in the areas of molecular diagnosis, infectious diseases, biosensors, and related fields.

Recent Advances in Biosensor Technology (Volume 1) is a comprehensive guide to the latest developments in biosensor technology, written by experts in bioengineering and biosensor development. The book is an essential resource for researchers and biomedical engineers interested in the latest developments in biosensor technology. The volume covers the applications of biosensors in different fields. It features 9 chapters that cover key themes in this area, including biosensors for natural bioactive compounds, wearable biosensors in healthcare, 3D bioprinting and biosensors, biosensors for neurodegenerative diseases, protein biosensing and pathogen detection, biosensors for diabetes diagnosis, paper-based biosensors in diagnostics, enzymatic biosensors and their applications, and nanobiosensors in agriculture. One of the key features of this book is its detailed discussion of the novel research findings in biosensor technology, providing readers with the most up-to-date information in the field. Each chapter includes a comprehensive review of relevant literature, as well as practical examples to demonstrate the potential applications of biosensors in various fields. Furthermore, this book includes detailed references for further reading, making it an excellent resource for readers looking to deepen their understanding of biosensor technology.

BIOSENSORS NANOTECHNOLOGY The second edition of Biosensors Nanotechnology comprises 20 chapters and discusses a wide range of applications exploited by biosensors based on nanoparticles including new domains of bionics, power production and computing. The biosensor industry began as a small, niche activity in the 1980s and has since developed into a large, global industry. Nanomaterials have substantially improved not only non-pharmaceutical and healthcare uses, but also telecommunications, paper, and textile manufacturing. Biological sensing assists in the understanding of living systems and is used in a variety of sectors, including medicine, drug discovery, process control, environmental monitoring, food safety, military and personal protection. It allows for new opportunities in bionics, power generation and computing, all of which will benefit from a greater understanding of the bio-electronic relationship, as advances in communications and computational modeling enable us to reconsider how healthcare is offered and R&D and manufacturing are enhanced. In this fast-evolving discipline, the combination of nanoscale materials with biosensor technology has gained a lot of traction. Nanostructures have been used to increase the adherence of biosensor materials to electrode surfaces, print nano barcodes on biomaterials, increase the pace of bio-responses, and amplify the electric signal. Some of the topics discussed in the book include: Bioreceptors for Cells; Bioreceptors for Enzymatic Interactions; Dendrimer-Based Nanomaterials for Biosensors; Biosensors in 2D Photonic Crystals; Bioreceptors for Affinity Binding in Theranostic Development; Biosensors for Glucose Monitoring; Metal-Free Quantum Dots-Based Nanomaterials for Biosensors; Bioreceptors for Microbial Biosensors; Plasmonic Nanomaterials in Sensors; Magnetic Biosensors; Biosensors for Salivary Biomarker Detection of Cancer and Neurodegenerative Diseases; Design and Development of Fluorescent Chemosensors for the Recognition of Biological Amines and Their Cell Imaging Studies; Application of Optical Nanoprobes for Supramolecular Biosensing; In Vivo Applications for Nanomaterials in Biosensors; Biosensor and Nanotechnology for Diagnosis of Breast Cancer; Bioreceptors for Antigen–Antibody Interactions; Biosensors for Paint and Pigment Analysis; Bioreceptors for Tissue; Biosensors for Pesticide Detection; and Advances in Biosensor Applications for Agroproducts Safety. Audience The book is written for a large and broad readership including researchers, industry engineers, and university graduate students from diverse backgrounds such as chemistry, materials science, physics, pharmacy, medical science, biomedical engineering, electronics engineering, and nanotechnology.