Blood Pressure Disorders In Diabetes Mellitus

This book provides an in-depth and up-to-date review of the association between blood pressure disorders and diabetes mellitus. In addition, it discusses the specific role of hemodynamic alterations on the vasculature of various target organs (the retina, kidney, brain, and gravid uterus), topics that are infrequently considered and or acknowledged by clinicians. Covering all aspects of the interaction between metabolic and hemodynamic factors, the book presents the diverse perspectives of the contributing authors and extensive discussions of issues including diabetic kidney disease, diabetic hypertensive phenotypes and postural hypotension.

Diabetes and hypertension have evolved as two of the modern day epidemics affecting millions of people around the world. These two common co-morbidities lead to substantial increase in cardiovascular disease, the major cause of morbidity and mortality of adults around the world. In Diabetes and Hypertension: Evaluation and Management, a panel of renowned experts address a range of critical topics -- from basic concepts in evaluation and management of diabetes and hypertension, such as dietary interventions, to evaluation and management of secondary hypertension in clinical practice. Other chapters focus on high cardiovascular risk populations such as those with coronary heart disease, chronic kidney disease and minority patients. In addition, evolving concepts and new developments in the field are presented in other chapters, such as prevention of type 2 diabetes and the epidemic of sleep apnea and its implication for diabetes and hypertension evaluation and management. An important title covering two of the most troubling disorders of our time, Diabetes and Hypertension: Evaluation and Management will provide the busy practitioner with cutting edge knowledge in the field as well as practical information that can translate into better care provided to the high-risk population of diabetics and hypertensive patients.

Diabetes mellitus, particularly non-insulin-dependent diabetes Type 2, is a common disease and, even though insulin has been around for seventy years, this endocrine disorder still reduces the life expectancy of diabetic patients because of the development of long-term complications, including hypertension. Hypertension occurs twice as often in dia

The association of diabetes mellitus and hypertension has been well known for a long time. However, the important impact of hypertension on the development of chronic complications of diabetes and on the prognosis of the diabetic patient has only recently been realized. The increasing number of patients with endstage diabetic nephropathy who need regular dialysis or renal transplantation reflects only one important aspect of this problem. As new targets for the treatment of hypertension were considered, it became evident, that drug treatment of hypertension in diabetics must take side effects into account which may be negligible in the nondiabetic patient. Basic research has granted much new insight into the mechanisms which function to link diabetes, kidney function, hypertension, and vascular disease. As a result of the high specialisation in research, such new information diffuses only slowly out of the circles of experts into clinical practice. Therefore, it was a most rewarding initiative of the Bayer Company to sponsor a conference which aimed at a mutual exchange of ideas between clinicians and researchers who are experts in either hypertension or diabetes.

The first sporadic observations describing renal abnormalities in diabetes were published late in the 19th century, but systematic studies of the kidney in diabetes started only half a century ago after the paper by Cambier in 1934 and the much more famous study by Kimmelstiel and Wilson in 1936. These authors described two distinct features of renal involvement in diabetes: early hyperfiltration and late nephropathy. Diabetic nephropathy is, despite half a century of studies, still a very pertinent problem, renal disease in diabetes now being a very common cause of end-stage renal failure in Europe and North America and probably throughout the world. It is a very important part of the generalized vascular disease found in long-term diabetes as described by Knud Lundbaek in his mono graph Long-term Diabetes in 1953, published by Munks gaard, Copenhagen. Surprisingly, there has not been a comprehensive volume describing all aspects of renal involvement in diabetes, and the time is now ripe for such a volume summarizing the very considerable research activity within this field during the last decade and especially during the last few years. This book attempts to cover practically all aspects of renal involvement in diabetes. It is written by colleagues who are themselves active in the many fields of medical research covered in this volume: epidemiology, physiology and pathophysiology, laboratory methodology, and renal pathology. New studies deal with the dia gnosis and treatment of both incipient and overt nephropathy by metabolie, antihypertensive, and dietary invention.

DIABETES MELLITUS AND HYPERTENSION takes you straight to the practical information you need to care for patients today, such as how to assess a patient for hyperglycemic hyperosmolar nonketotic syndrome and how to intervene in a hypertensive crisis.

This report reviews the rationale for primary prevention of hypertension, strategies for prevention of hypertension, and efficacy of interventions to prevent hypertension. Includes policy recommendations.

Diabetes mellitus, particularly non-insulin-dependent diabetes Type 2, is a common disease and, even though insulin has been around for seventy years, this endocrine disorder still reduces the life expectancy of diabetic patients because of the development of long-term complications, including hypertension. Hypertension occurs twice as often in diabetic patients as in non-diabetic ones. The combination of diabetes and hypertension creates a greater risk of coronary artery disease which is the major cause of death in westernized societies. Bryan Williams and his international team of collaborators provide the reader with their views for treatment of diabetes associated with hypertension and the prevention of subsequent coronary artery disease and other disorders.