Breakthrough

Follow along as this New York Times bestselling author details the astonishing scientific discovery of the code to unleashing the human immune system to fight in this "captivating and heartbreaking" book (The Wall Street Journal). For decades, scientists have puzzled over one of medicine's most confounding mysteries: Why doesn't our immune system recognize and fight cancer the way it does other diseases, like the common cold? As it turns out, the answer to that question can be traced to a series of tricks that cancer has developed to turn off normal immune responses -- tricks that scientists have only recently discovered and learned to defeat. The result is what many are calling cancer's "penicillin moment," a revolutionary discovery in our understanding of cancer and how to beat it. In The Breakthrough, New York Times bestselling author of The Good Nurse Charles Graeber guides readers through the revolutionary scientific research bringing immunotherapy out of the realm of the miraculous and into the forefront of twenty-first-century medical science. As advances in the fields of cancer research and the human immune system continue to fuel a therapeutic arms race among biotech and pharmaceutical research centers around the world, the next step -- harnessing the wealth of new information to create modern and more effective patient therapies -- is unfolding at an unprecedented pace, rapidly redefining our relationship with this all-too-human disease. Groundbreaking, riveting, and expertly told, The Breakthrough is the story of the game-changing scientific discoveries that unleash our natural ability to recognize and defeat cancer, as told through the experiences of the patients, physicians, and cancer immunotherapy researchers who are on the front lines. This is the incredible true story of the race to find a cure, a dispatch from the life-changing world of modern oncological science, and a brave new chapter in medical history.

Featured in the 2018 movie Science Fair! A National Science Teachers Association Best STEM Book of 2017 In this acclaimed memoir, teen innovator and scientist Jack Andraka tells the story behind his revolutionary discovery. When a dear family friend passed away from pancreatic cancer, Jack was inspired to create a better method of early detection. At the age of fifteen, he garnered international attention for his breakthrough: a four-cent strip of paper capable of detecting pancreatic, ovarian, and lung cancers four hundred times more effectively than the previous standard. Jack's story is not just a story of dizzying international success; it's a story of overcoming depression and homophobic bullying and finding the resilience to persevere and come out. His account inspires young people, who he argues are the most innovative, to fight for the right to be taken seriously and to pursue our own dreams. Do-it-yourself science experiments are included in each chapter, making Breakthrough perfect for STEM curriculum. But above all, Jack's memoir empowers his generation with the knowledge that we can each change the world if we only have the courage to try.

BreakthroughBy Michael C. Grumley

A new shared world anthology featuring a who's who of science fiction writers including Larry Niven, Steven Perry and Gary Gygax. Pledged to stop the predator Khalians, the Fleet must win a decisive victory to break the war's deadlock--and bring peace to their worlds.

Breakthrough: Trusting God for Big Change in Your Church encourages leaders of churches that are struggling and wondering if it's time to close the doors on God's work through them, their family, their church, or their ministry. This book is especially for those who have the audacity to dare to imagine where a new window might open as an old door is closing. Breakthrough reveals gritty, well-grounded hope around every corner.

He heard it while participating in his camp-counseling job at age sixteen: "I am coming soon." Seeing no one was around him, author Franklyn Spence believed he had heard God's voice. More instances of God speaking to him, even through a vision of Jesus, left him overwhelmed spiritually and aware of his gifts for prophecy and healing. He recalls these faith-defining moments in his Christian testimony/self-help guide, Breakthrough into the Supernatural Realm. Growing up in his church, Franklyn remembers being taught God was distant, accessible only for special occasions. However, the God Franklyn experienced at camp was real, intimate and calling him to an impossible task. He states in his book God developing his faith through tests, whether healing a sparrow to praying for strangers, and frequently communicating with him. Franklyn wants readers to have the same relationship with God, hearing His voice as clear as he did at camp.

People don’t want to just walk through life but seek to walk into it. Life is far from perfect. Often, it’s full of hard choices. Waking up from a coma to discover his eighteen-year-old body contained seven stage-four cancerous tumors, Christopher Stewart’s battle for his life began. For Chris, the easy choice was to fight for his life. The hard one was choosing to be himself in the process. Through this journey, Chris saw firsthand that life is filled with challenge, fear, pain, and chaos but that there is also love and beauty to be found and good memories to be made. Breakthrough offers insight into how beautifully haunting our lives can be, as Chris tells how to: - let go of the expectations to be a pretender - every day choose to be yourself—the person you were destined to be - accept yourself for who you are - chase your dreams, because anything is obtainable! Chris was able to make a breakthrough. And through this book he believes that you can breakthrough too. By facing fear, chaos, and pain, you too can find a more meaningful life.

Harnessing technology for a better future Looking into the future is always difficult and often problematic—but sometimes it’s useful to imagine what innovations might resolve today’s problems and make tomorrow better. In this book, 15 distinguished international experts examine how technology will affect the human condition and natural world within the next ten years. Their stories reflect major ambitions for what the future could bring and offer a glimpse into the possibilities for achieving the UN’s ambitious Sustainable Development Goals. The authors were asked to envision future success in their respective fields, given the current state of technology and potential progress over the next decade. The central question driving their research: What are likely technological advances that could contribute to the Sustainable Development Goals at major scale, affecting the lives of hundreds of millions of people or substantial geographies around the globe. One overall takeaway is that gradualist approaches will not achieve those goals by 2030. Breakthroughs will be necessary in science, in the development of new products and services, and in institutional systems. Each of the experts responded with stories that reflect big ambitions for what the future may bring. Their stories are not projections or forecasts as to what will happen; they are reasoned and reasonable conjectures about what could happen. The editors’ intent is to provide a glimpse into the possibilities for the future of sustainable development. At a time when many people worry about stalled progress on the economic, social, and environmental challenges of sustainable development, Breakthrough is a reminder that the promise of a better future is within our grasp, across a range of domains. It will interest anyone who wonders about the world’s economic, social, and environmental future.