Carbon Nanostructures For Biomedical Applications

This book provides a holistic compilation on applications of carbon nanostructures, especially in advanced healthcare applications. It comprises chapters on utility of diverse multifunctional nanocarriers in drug delivery and biomedical applications, especially emphasizing on the synthesis and characterizations of nanosystems along with surface engineering approaches used for active targeting of the drugs. Moreover, the chapters also include the recent updates on the applications of the nanocarriers to fulfill the needs of various healthcare systems.

This book explores the potential of multi-functional carbon nanotubes for biomedical applications. It combines contributions from chemistry, physics, biology, engineering, and medicine. The complete overview of the state-of-the-art addresses different synthesis and biofunctionalisation routes and shows the structural and magnetic properties of nanotubes relevant to biomedical applications. Particular emphasis is put on the interaction of carbon nanotubes with biological environments, i.e. toxicity, biocompatibility, cellular uptake, intracellular distribution, interaction with the immune system and environmental impact. The insertion of NMR-active substances allows diagnostic usage as markers and sensors, e.g. for imaging and contactless local temperature sensing. The potential of nanotubes for therapeutic applications is highlighted by studies on chemotherapeutic drug filling and release, targeting and magnetic hyperthermia studies for anti-cancer treatment at the cellular level.

Carbon nanostructures, namely fullerenes, single and multiwall carbon nanotubes, graphene as well as the most recent graphene quantum dots and carbon nanodots, have experienced a tremendous progress along the last two decades in terms of the knowledge acquired on their chemical and physical properties. These insights have enabled their increasing use in biomedical applications, from scaffolds to devices. Edited by renowned experts in the subject, this book collects and delineates the most notable advances within the growing field surrounding carbon nanostructures for biomedical purposes. Exploration ranges from fundamentals around classifications to toxicity, biocompatibility and the immune response. Modified nanocarbon-based materials and emergent classes, such as carbon dots and nanohorns are discussed, with chapters devoted from carriers for drug delivery and inhibitors of emergent viruses infection, to applications across imaging, biosensors, tissue scaffolding and biotechnology. The book will provide a valuable reference resource and will extensively benefit researchers and professionals working across the fields of chemistry, materials science, and biomedical and chemical engineering.

This book covers a wide range of topics relating to carbon nanomaterials, from synthesis and functionalization to applications in advanced biomedical devices and systems. As they possess unique and attractive chemical, physical, optical, and even magnetic properties for various applications, considerable effort has been made to employ carbon nanomaterials (e.g., fullerenes, carbon nanotubes, graphene, nanodiamond) as new materials for the development of novel biomedical tools, such as diagnostic sensors, imaging agents, and drug/gene delivery systems for both diagnostics and clinical treatment. Tremendous progress has been made and the scattered literature continues to grow rapidly. With chapters by world-renowned experts providing an overview of the state of the science as well as an understanding of the challenges that lie ahead, Carbon Nanomaterials for Biomedical Applications is essential reading not only for experienced scientists and engineers in biomedical and nanomaterials areas, but also for graduate students and advanced undergraduates in materials science and engineering, chemistry, and biology.

This book represents a critical evaluation of the most recent discoveries about carbon nanotubes and includes a cautious description of their impact on personal health and environmental pollution. It also offers an overview of the main research groups around the world which have been focusing their efforts on the exploitation of this intriguing material, with the purpose of inspiring young scientists to follow their pathway.

This book explores the potential of multi-functional carbon nanotubes for biomedical applications. It combines contributions from chemistry, physics, biology, engineering, and medicine. The complete overview of the state-of-the-art addresses different synthesis and biofunctionalisation routes and shows the structural and magnetic properties of nanotubes relevant to biomedical applications. Particular emphasis is put on the interaction of carbon nanotubes with biological environments, i.e. toxicity, biocompatibility, cellular uptake, intracellular distribution, interaction with the immune system and environmental impact. The insertion of NMR-active substances allows diagnostic usage as markers and sensors, e.g. for imaging and contactless local temperature sensing. The potential of nanotubes for therapeutic applications is highlighted by studies on chemotherapeutic drug filling and release, targeting and magnetic hyperthermia studies for anti-cancer treatment at the cellular level.

FUNCTIONALIZED CARBON NANOTUBES FOR BIOMEDICAL APPLICATIONS The book highlights established research and technology on current and emerging trends and biomedical applications of functionalized carbon nanotubes by providing academic researchers and scientists in industry, as well as high-tech start-ups, with knowledge of the modern practices that will revolutionize using functionalized carbon nanotubes. Nanotechnology suggests fascinating opportunities for a variety of applications in biomedical fields, including bioimaging and targeted delivery of biomacromolecules into cells. Numerous strategies have been recommended to functionalize carbon nanotubes with raised solubility for efficient use in biomedical applications. Functionalized carbon nanotubes have unique arrangements and extravagant mechanical, thermal, magnetic, optical, electrical, surface, and chemical properties, and the combination of these features gives them widespread biomedical applications. Functionalized carbon nanotubes are relatively flexible and interact with the cell membranes and penetrate different biological tissues owing to a “snaking” effect, therefore both the pharmacological and toxicological profiles of functionalized carbon nanotubes have gathered much attention in recent times. This book covers a broad range of topics relating to carbon nanotubes, from synthesis and functionalization to applications in advanced biomedical devices and systems. As they possess unique and attractive physical, chemical, optical, and even magnetic properties for various applications, considerable effort has been made to employ functionalized carbon nanotubes as new materials for the development of novel biomedical tools, such as diagnostic sensors, imaging agents, and drug/gene delivery systems for both diagnostics and clinical treatment. Audience The book is intended for a very broad audience of researchers and scientists working in the fields of nanomaterials, nanomedicine, bioinspired nanomaterials, nanotechnology, and biomedical application of nanomaterials.

Recent advancements and research in nanotechnology, biotechnology, materials engineering the applications of nanomaterial are evolving. Carbon nanotubes (CNT) and CNT-based systems possess unique chemical, physical, and biological properties that make them good candidates in biomedical applications, but they also have some inherent properties that cause great concern about their biosafety. This volume explores the practical applications of carbon nanotubes in biomedical science and human health. It discusses the synthesis, properties, modification, and recent progress of carbon nanotubes and their applications for biosensing, cancer treatment, antibacterial therapy, tissue engineering, targeted drug delivery, and toxicity. It relays the potential and promise of carbon-based nanomaterials for host of applications while also looking at the challenges in synthesis, characterization, and applications of nanomaterials and how to overcome them.