Carbon Nanotubes In Drug And Gene Delivery

Recent important discoveries and developments in nanotechnology have had a remarkable and ever-increasing impact on many industries, especially materials science, pharmaceuticals, and biotechnology. Nanocarriers have been investigated for a wide variety of different medical applications. Some examples of these nanocarriers include polymersomes, liposomes, micelles and carbon-based nanomaterials. Within this book, the authors describe different features of carbon nanotubes (CNTs), survey the properties of both the multi-walled and single-walled varieties, and cover their applications in drug and gene delivery. In addition, the book explains the structure and properties of CNTs prepared by different method, and discussed their isolation and purification. The future of CNTs in the field of biomedical science will depend on minimizing their adverse effects by careful study of their structure and properties.

Emerging Applications of Carbon Nanotubes in Drug and Gene Delivery brings together principles behind the formation, characterization and development of carbon nanotubes (CNTs) with recent advances in drug and gene delivery applications. The book begins with an introduction to the unique properties of CNTs, as well as the various synthesis, purification and functionalization methods available. Later chapters cover drug and gene delivery using CNTs for therapeutic applications, comparing advantages and disadvantages of each. The book then goes on to discuss toxicity and safety challenges in using CNTs in biomedicine, with a forward-look at regulatory requirements and clinical translations. This book offers a detailed reference for materials scientists, biomedical engineers, pharmaceutical scientists and geneticists interested in CNTs and nanomedicine. Provides focused coverage of nanotubes for use in drug and gene delivery applications, offering much-needed detail amongst broader nanomedicine texts Details the properties, characterization, synthesis, functionalization and applications of CNTs in drug and gene delivery Discusses toxicity, safety and regulatory aspects of CNTs, with a look towards the clinical translation of CNTs

This book provides a detailed introduction to carbon nanotubes (CNTs) for targeted drug delivery. After a brief overview of the classification, preparation, and characterization of carbon nanotubes, it focuses on their use in targeted drug delivery. It presents CNTs for brain targeting, ocular targeting, cancer targeting, and lymphatic targeting, as well as antibody therapy. The book also includes chapters on carbon nanotubes for controlled drug delivery, transdermal drug delivery, solubility enhancement, vaccine delivery, gene delivery, and as quantum dots. Last but not least, it addresses the absorption and transportation of CNTs, toxicity and regulatory considerations, as well as clinical trials and the market status of CNTs. The book offers a comprehensive, self-contained reference guide, with all topics covered concisely and with the help of figures, tables and flowcharts.

Fullerens, Graphenes and Nanotubes: A Pharmaceutical Approach shows how carbon nanomaterials are used in the pharmaceutical industry. While there are various books on the carbonaceous nanomaterials available on the market, none approach the subject from a pharmaceutical point-of-view. In this context, the book covers different applications of carbonaceous nanomaterials. Chapters examine different types of carbon nanomaterials and explore how they are used in such areas as cancer treatments, pulse sensing and prosthetics. Readers will find this book to be a valuable reference resource for those working in the areas of carbon materials, nanomaterials and pharmaceutical science. Explains how the unique properties of carbon-based nanomaterials allow them to be used to create effective drug delivery systems Covers how carbon-based nanomaterials should be prepared for use in pharmaceutical applications Discusses the relative toxicity of a range of carbon-based nanomaterials Considers the safety of their use in different types of drugs

Nanotechnology-Based Approaches for Targeting and Delivery of Drugs and Genes provides an overview of the important aspects of nanomedicine in order to illustrate how to design and develop novel and effective drug delivery systems using nanotechnology. The book is organized into three sections, beginning with an introduction to nanomedicine and its associated issues. Section two discusses the latest technologies in nanomedicine, while the third section covers future developments and challenges in the field. By focusing on the design, synthesis, and application of a variety of nanocarriers in drug and gene delivery, this book provides pharmaceutical and materials science students, professors, clinical researchers, and industry scientists with a valuable resource aimed at tackling the challenges of delivering drugs and genes in a more targeted manner. Explores a wide range of promising approaches for the diagnosis and treatment of diseases using the latest advances in cutting-edge nanomedical technologies Contains contributions from world-renowned experts and researchers working in the area of nanomedicine and drug delivery Covers the associated challenges and potential solutions to working with nanotechnology in drug delivery Highlights crucial topics, such as biopharmaceutical and toxicity issues, quality by design, drug targeting, and more

Focusing on nanoparticulate nanocarriers and recent advances in the field of drug delivery, the volume begins with chapters that provide an informative introduction to polymeric nanoparticles—their general physicochemical features and characteristics, their applications in drug delivery systems, and the challenges involved. Specific applications are discussed, with attention paid to treatment of particular diseases and disorders and the targeting of specific organs. Part 2 looks at more specific applications and techniques of nanoparticulate nanocarriers for drug delivery, such as the use of magnetic nanoparticles, gold nanoparticles in therapeutics, and superparamagnetic iron oxide nanoparticles (SPIONs) for the treatment of cancer. Part 3 discusses lipid-based nanoparticulates for various applications, including skin care. The last section of the book explores some of the newer nanoarchitectures, including dendrimers in gene delivery and carbon nanotubes for drug delivery. Together, the insightful research presented here provides valuable information for those involved in this area, including scientists and researchers and faculty and upper-level students, as well as for industry professionals.

Carbon-Based Nanocarriers for Drug Delivery enlists the latitudes and advancements in the synthesis processes, functionalization, and applications of carbon-based nanomaterials (CBNs) in targeted drug delivery systems (DDSs). It covers the applicability and suitability of CBNs as nanocarriers for efficient drug delivery application via elucidating the recent advancements in CBNs, their functionalized and innovative derivatives, and the relevant case studies. The book explores the necessity, efficacy, toxicological aspects, and challenges for the application of CBN in targeted DDSs. Some of the features of this book are provided as follows: Provides elaborative description on significance and adaptability of carbon-based nanomaterial in targeted drug delivery for wide ranges of therapeutics Delivers a full-spectrum discussion on drug delivery through carbon-based nanocarriers Explores each carbon-based nanocarrier fundamentally for its drug and gene-delivery-related applications Describes critical discussion on various toxicological effects over the utilization of these nanocarriers Embraces existing as well as novel technologies/methodologies related to the synthesis and functionalization of CBNs, including graphene, graphene oxide, carbon quantum dots, carbon nanotube, fullerene, and smart carbon-based nanocarriers This book is aimed at researchers and graduate students in materials and pharmaceutical engineering, including drug delivery systems.