Casebook In Clinical Pharmacokinetics And Drug Dosing

A STEP-BY-STEP APPROACH TO DESIGNING ACCURATE DOSING REGIMENS Casebook in Pharmacokinetics and Drug Dosing uses real-life cases to teach pharmacy students, pharmacists, and clinical pharmacists how to apply pharmacokinetics to formulate proper dosing regimens. In order to be as clinically relevant as possible, the book not only discusses drugs with readily available therapeutic serum levels, but places equal emphasis on high-alert agents with narrow therapeutic indexes. Each drug chapter is written by clinical pharmacists who have hands-on experience in drug dosing and includes an overview of the drug’s pharmacology, including: Indications Mec hanisms of action Toxicities Pharmacokinetics There is comprehensive review and discussion of each drug's bioavailability, volume of distribution, clearance, half-life, therapeutic drug level monitoring, drug interactions, dosing, and availability. Each chapter is enhanced by numerous patient cases with clear step-by-step answers and explanations. Calculations, equations, and dosing recommendations are provided for each case.

In the complex field of pharmacokinetics, one reference guide has an identity all its own: Clinical Pharmacokinetics. Now the fully updated 5th edition brings to experienced practitioners and students alike the fresh information they need most: · Content organized for fast reference to specific drugs · The latest on dosing in obese and overweight patients · Dosing considerations for neonatal, pediatric and geriatric patients · A look at protein binding and its implications · Population values for a variety of drugs to initiate dosing · Drug dosing in renal disease and creatinine clearance estimation A Distinctively Straightforward Guide is Now Even Better The 5th Edition of Clinical Pharmacokinetics is completely revised and updated, making a handy clinical guide even easier to use than ever. · Reorganized content features two sections: Basic Concepts and Special Populations and Specific Drugs and Drug Classes · Sections on special populations, including Dosing in Overweight and Obese Patients, have been conveniently grouped together · Comprehensive introduction covers means, measurements and monitoring · Also conveniently placed up front” a glossary of pharmacokinetics basics and commonly used equations

Short Description: This popular teaching and self-instructional text makes it easier than ever to acquire a strong foundation in the basic principles of pharmacokinetics.

'Applied Clinical Pharmacokinetics' features practically-oriented coverage of drug dosing and monitoring. It focuses on the latest standardized techniques and approaches to patient-specific dosing and provides the most current information on recently monitored drugs.

New sections on dosing strategies in all chapters. New chapter on sirolimus under the Immunosuppressants section. Essential information on drug dosing in special populations, including patients with renal and hepatic disease, obesity, and congestive heart failure. 30% of chapters extensively revised, others lightly updated

Pharmacokinetics is the study of the process of drug absorption, distribution, metabolism and elimination. The aim of applying pharmacokinetic principles is to individualise the dose of drug, and optimise the outcome achieved in each patient. Its application reduces the chance of under-treatment, inadvertent poisoning, and dose related adverse effects. This new edition is specifically aimed at supporting undergraduate studies in pharmacokinetics, and has a strong emphasis on the application of pharmacokinetics in routine clinical practice. Clinical Pharmacokinetics also includes several case studies and 'questions and answers' to further aid understanding and revision.

Concepts in Clinical Pharmacokinetics, 7th edition, is the fundamental reference for learning the basic, foundational pharmacokinetics concepts and how to apply them to dosing of drugs in clinical practice. Content is broken into 15 easy-to-follow lessons, perfect for a semester. Practice quizzes in 11 chapters to chart progress Four chapters completely devoted to clinical cases More information on hemodialysis More on pharmacogenetics More on plasma concentration versus time curve (AUC) calculations A phenytoin “cheat sheet” to help you through the calculations maze New vancomycin cases based on higher desired vancomycin levels and trough-only dose estimations More on modified diet in renal disease (MDRD) formula versus Cockcroft-Gault (CG) formula methods More theory and problems on extended interval aminoglycosides

Designed for pharmacists and clinicians responsible for adjusting drug dosages based on the patient blood serum concentrations and other parameters, this indispensable, portable reference offers a variety of ways to perform pharmacokinetic calculations. Features calculation methods, algorithms for choosing the best calculation method, and case studies.