Cellular Radiobiology

This textbook covers all aspects of radiation, radiotherapy and their effects. The book, initially published in France, has been updated and expanded in this English version. It includes a thorough discussion of recent advances, such as a better understanding of the molecular basis of cellular effects and cell radiosensitivity.There is a study of the mechanmism by which dose and overall duration of radiotherapy can introoduce differential effects between normal and neoplastic tissues and recent data on radiocarcinogenesis in man and experimental animals is provided.

This new edition of A.H.W. Nias' successful book provides an updated and revised introduction to quantitative radiobiology, particularly, to those aspects of the subject which have a practical application. Radiation is used to cure cancer but can also cause it. Radiation is also used in medical diagnosis and in nuclear power stations. In these areas, where questions of benefit and detriment arise, the biological effects of the radiation can now be predicted. There are few aspects of life where risk estimates are so firmly founded on quantitative data. This is not only because of the precision with which radiation dose can be measured but also because of the large body of radiobiological observations which have been made since X-rays were discovered. Written by a scientist with many years experience in the field, An Introduction to Radiobiology will appeal to a wide variety of readers who need to understand the mechanisms by which ionizing radiation causes cellular damage. It will be of interest to technologists in radiation therapy, nuclear medicine and diagnostic radiography, cancer research students and technicians, medical physicists, trainee radiotherapists and nuclear medicine specialists. Reviews of the First Edition: "In summary, this is an excellent general text that should fill an important gap in many teaching needs, especially those where the major focus is on the biological effects of radiation on humans." Journal of the National Cancer Institute "This is undoubtedly one of the better introductions to the subject which I have read, and I would certainly recommend it not only to beginners but also to mature students of the subject." The British Journal of Radiology

This textbook covers many aspects of radiation, radiotherapy and their effects. It includes a discussion of recent advances, such as the molecular basis of cellular effects and cell radiosensitivity, radiocarcinogenesis and how radiotherapy can affect normal and neoplastic tissues.

Publisher's Note: Products purchased from 3rd Party sellers are not guaranteed by the Publisher for quality, authenticity, or access to any online entitlements included with the product. Considered the “gold standard” in the field for over 45 years, Radiobiology for the Radiologist combines traditional and molecular radiation biology principles and appeals to students, residents, and veteran clinical practitioners. This edition continues the two-part format of previous editions and features brand-new chapters, thoroughly updated content, and hundreds of figures that provide a visual context to the information in each chapter.

This handbook presents the most current information on the effects of ionizing radiation on mammalian cells, with emphasis on human tissues. The dose-effect relationship is emphasized in a quantitative manner. The book contains up-to-date data on the late effects of low levels of radiation on humans. It also provides some of the late consequences of radiation therapy detected among cancer survivors.

Radiobiology Self-Assessment Guide--a companion to the Radiation Oncology Self-Assessment Guide and Physics in Radiation Oncology Self-Assessment Guide--is a comprehensive review for practitioners of radiation oncology looking to enhance their knowledge of radiobiology. It covers in depth the principles of radiobiology as applied to radiation oncology along with their clinical applications. To foster retention of key concepts and data, the resource utilizes a user-friendly "flash card" question and answer format with over 700 questions. The questions are supported by detailed answers and rationales along with reference citations for source information. The guide is comprised of 29 chapters and cover topics commonly found on the radiation and cancer biology portion of the radiation oncology board examination. Aspects of basic radiobiology covered include fundamentals such as cell cycle, cell survival curves and interactions of radiation with matter, and acute and long-term sequelae of radiation. Modern concepts such as immunotherapy, radiogenomics, and normal and cancer stem cells are also included. Focused and authoritative, this must-have review provides the expertise of faculty from the Department of Radiation Oncology at the Cleveland Clinic Taussig Cancer Institute and Lerner Research Institute. Key Features: Provides a comprehensive study guide for the Radiation and Cancer Biology portion to the Radiation Oncology Board Exam Includes more than 700 questions with detailed answers and rationales on flip pages for easy, flash card-like review Includes essential review of cancer biology concepts such as immunotherapy, stem cells, gene therapy, chemotherapy and targeted agents Content provided by a vast array of contributors, including attending radiation oncology physicians, physicists, and radiation oncology residents

Provides an introduction to quantitative radiobiology with emphasis on practical aspects of the subject. Readers will gain a ready understanding of both the very fast processes which initiate damage in irradiated tissue and the kinetic patterns in which such damage is expressed at the cellular level. Among the topics considered are reparable damage, densely ionizing radiation, normal and malignant cells and whole body regulation. These and other aspects of radiation biology are described in detail at a level appropriate to readers with a basic knowledge of mammalian cell biology.