Chemistry In Action

The second revised edition of an accessible A-level chemistry text, containing additional worked examples and exercises, and covering new topics such as AIDS research, High Temperature Superconductivity and the greenhouse effect.

Explanation of the fundamentals of chemistry including the chemical elements, organic chemistry, and biochemistry.

Astrochemistry and Astrobiology is the debut volume in the new series Physical Chemistry in Action. Aimed at both the novice and experienced researcher, this volume outlines the physico-chemical principles which underpin our attempts to understand astrochemistry and predict astrobiology. An introductory chapter includes fundamental aspects of physical chemistry required for understanding the field. Eight further chapters address specific topics, encompassing basic theory and models, up-to-date research and an outlook on future work. The last chapter examines each of the topics again but addressed from a different angle. Written and edited by international experts, this text is accessible for those entering the field of astrochemistry and astrobiology, while it still remains interesting for more experienced researchers.

Summary CMIS and Apache Chemistry in Action is a comprehensive guide to the CMIS standard and related ECM concepts, written by the authors of the standard. In it, you'll tackle hands-on examples for building applications on CMIS repositories from both the client and the server sides. You'll learn how to create new content-centric applications that install and run in any CMIS-compliant repository. About The Technology Content Management Interoperability Services (CMIS) is an OASIS standard for accessing content management systems. It specifies a vendor-and language-neutral way to interact with any compliant content repository. Apache Chemistry provides complete reference implementations of the CMIS standard with robust APIs for developers writing tools, applications, and servers. About This Book CMIS and Apache Chemistry in Action is a comprehensive guide to the CMIS standard and related ECM concepts. In it, you'll find clear teaching and instantly useful examples for building content-centric client and server-side applications that run against any CMIS-compliant repository. In fact, using the CMIS Workbench and the InMemory Repository from Apache Chemistry, you'll have running code talking to a real CMIS server by the end of chapter 1. This book requires some familiarity with content management systems and a standard programming language like Java or C#. No exposure to CMIS or Apache Chemistry is assumed. Purchase of the print book includes a free eBook in PDF, Kindle, and ePub formats from Manning Publications. What's Inside The only CMIS book endorsed by OASIS Complete coverage of the CMIS 1.0 and 1.1 specifications Cookbook-style tutorials and real-world examples About the Authors Florian Müller, Jay Brown, and Jeff Potts are among the original authors, contributors, and leaders of Apache Chemistry and the OASIS CMIS specification. They continue to shape CMIS implementations at Alfresco, IBM, and SAP. Table of Contents PART 1 UNDERSTANDING CMIS Introducing CMIS Exploring the CMIS domain model Creating, updating, and deleting objects with CMIS CMIS metadata: types and properties Query PART 2 HANDS-ON CMIS CLIENT DEVELOPMENT Meet your new project: The Blend The Blend: read and query functionality The Blend: create, update, and delete functionality Using other client libraries Building mobile apps with CMIS PART 3 ADVANCED TOPICS CMIS bindings Security and control Performance Building a CMIS server

Standard medicinal chemistry courses and texts are organized by classes of drugs with an emphasis on descriptions of their biological and pharmacological effects. This book represents a new approach based on physical organic chemical principles and reaction mechanisms that allow the reader to extrapolate to many related classes of drug molecules. The Second Edition reflects the significant changes in the drug industry over the past decade, and includes chapter problems and other elements that make the book more useful for course instruction. New edition includes new chapter problems and exercises to help students learn, plus extensive references and illustrations Clearly presents an organic chemist's perspective of how drugs are designed and function, incorporating the extensive changes in the drug industry over the past ten years Well-respected author has published over 200 articles, earned 21 patents, and invented a drug that is under consideration for commercialization

An ever-increasing demand for better drugs, elevated safety standards, and economic considerations have all led to a dramatic paradigm shift in the way that drugs are being discovered and developed. Known as rational drug design, this contemporary process is defined by three main steps: the discovery of lead compounds, surgical manipulation to deve

An integrated view of chiral drugs from concept and synthesisto pharmaceutical properties Chirality greatly influences a drug's biological and pharmacological properties. In an effort to achieve more predictable results from chiral drugs, the Food and Drug Administration now requires that these medicines be as pure as possible, which places great demands on drug synthesis, purification, analysis, and testing. To assist researchers in acquiring the essential knowledge to meet these rigid guidelines, Chiral Drugs focuses on three vital chiral technologies asymmetric synthesis, biocatalytic process, and chiral resolution to offer details on the basic concepts, key developments, and recent trends in chiral drug discovery, along with: The history of chiral drugs development and industrial applications of chiral technologies A section listing twenty-five approved or advanced-trial chiral drugs that lists each drug name, chemical name and properties, a representative synthetic pathway, pharmacological characterizations, and references An interdisciplinary approach combining synthetic organic chemistry, medicinal chemistry, and pharmacology Nearly two-thirds of the drugs on today's market are chiral drugs. Reducing and eliminating their negative characteristics is an ongoing and serious challenge for the pharmaceutical industry. With its well-balanced approach to covering each important aspect of chirality, Chiral Drugs champions important strategies for tipping the medical scale in a positive direction for the production of more effective and safer drugs.