Cidnp And Rate Processes Of Radicals

Elucidating Organic Reaction Mechanisms using photo-CIDNP Spectroscopy, by Martin Goez. Parahydrogen Induced Polarization by Homogeneous Catalysis: Theory and Applications, by Kerstin Münnemann et al. Improving NMR and MRI Sensitivity with Parahydrogen, by R. Mewis & Simon Duckett. The Solid-state Photo-CIDNP Effect, by Jörg Matysik et al. Parahydrogen-induced Polarization in Heterogeneous Catalytic Processes, by Igor Koptyug et al. Dynamic Nuclear Polarization Enhanced NMR Spectroscopy, by U. Akbey & H. Oschkinat. Photo-CIDNP NMR Spectroscopy of Amino Acids and Proteins, by Lars T. Kuhn.

Recently there have been major developments in the experimental techniques available for the study of the primary events following the absorption of ultra-violet and visible radiation by biological systems. These techniques, which include absorption, emission, resonance Raman, electron spin resonance, nuclear magnetic resonance and photoacoustic spectroscopies, can be used to study the fate of transient species with lifetimes ranging from seconds to nanoseconds and extending in some cases, such as laser flash photolysis, to pico 12 15 (10- S)- and even femtoseconds (10- s). In parallel with these developments there has been a dramatic increase in the use of light in medicine via the direct photochemical alteration of endogenous molecules (phototherapy) or via the photoactivation of drugs in the skin or other tissue (photochemotherapy). Thus neonatal hyperbili rubinaemia can be routinely treated by phototherapy and psoriasis is frequently treated by PUVA photochemotherapy. A promising new photo chemotherapy used the phototoxicity of porphyrin drugs activated by red light to destroy solid malignant tumors. While some of the overall qualitative effects of such treatments are known, only recently have we begun to understand the associated molecular mechanisms. The primary molecular processes involve short-lived species. The pur pose of this Advanced Study Institute was to review some newer experi mental techniques for the study of such species, the application of these techniques to biological and medical systems and to examine the value of such information in phototherapeutic situations.

Examining the formation, transformation, and application of ion radicals in typical conditions of organic synthesis, Organic Ion Radicals: Chemistry and Applications explains the reactions and principles of ion radical chemistry. The author addresses methods of determining ion- radical mechanisms and controlling ion radical reactions, issues relati

This volume contains the lectures given at the NATO Advanced Study Institute "The Study of Fast Processes and Labile Species in Chemistry and Molecular Biology Using Ionising Radiation" held in Capri, Italy, September 7-l8th 1981. The aim of the Institute was to summarise the present position of the use of pulsed ionising radiation in chemical and biological chemical research. For background an outline of the basic radiation chemistry and physics involved and descriptions of techniques and equipment in current use was presented. It was followed by comprehensive coverage of the state of this research to date in various areas of chemistry and biological chemistry. It was hoped to demonstrate to researchers not directly involved with ionising radiation how this technique is now at a stage in its development where it can have wider applications in various branches of chemistry and biology. The fifty participants did indeed form a wide spectrum of scientific interest covering inorganic, physical and organic chemistry, molecular physics, molecular biology, radiobiology and bacteriology. They also represented a wide variety of countries viz. Belgium, China, Denmark, France, Germany, Greece, Holland, Hungary, India, Italy, Poland, Turkey, U.S.A., U.K. and Yugoslavia.

For those wanting to become rapidly acquainted with specific areas of NMR, this title provides unrivalled scope of coverage.

Setting the pace for progress and innovation . . . ADVANCES IN PHOTOCHEMISTRY More than a simple survey of the current literature, Advances in Photochemistry offers critical evaluations written by internationally recognized experts. These pioneering scientists offer unique and varied points of view of the existing data. Their articles are challenging as well as provocative and are intended to stimulate discussion, promote further research, and encourage new developments in the field. In this volume Spectroscopy and Photochemistry of Polyatomic Alkaline Earth-Containing Molecules PETER F. BERNATH Photochemically Induced Dynamic Nuclear Polarization MARTIN GOEZ Photophysics of Gaseous Aromatic Molecules: Excess Vibrational Energy Dependence of Radiationless Processes EDWARD C. LIM Lanthanide Complexes of Encapsulating Ligands as Luminescent Devices NANDA SABBATINI, MASSIMO GUARDIGLI, AND ILSE MANET Advances in the Measurement of Correlation in Photoproduct Motion CHRISTOPHER G. MORGAN, MARCEL DRABBELS, AND ALEC M. WODTKE

Advances in Physical Organic Chemistry