Clinical Applications Of Magnetoencephalography

This book presents an overview of the recent advances in clinical applications of magnetoencephalography (MEG). With the expansion of MEG to neuroscience, its clinical applications have also been actively pursued. Featuring contributions from prominent experts in the fields, the book focuses on the current status of the application of MEG, not only to each nervous system but also to various diseases such as epilepsy, neurological disorders, and psychiatric disorders, while also examining the feasibility of using MEG for these diseases. Clinical Applications of Magnetoencephalography offers an indispensable resource for neurologists, neurosurgeons, pediatricians, and psychiatrists, as well as researchers in the field of neuroscience.

This is a practical book on MEG that covers a wide range of topics. The book begins with a series of reviews on the use of MEG for clinical applications, the study of cognitive functions in various diseases, and one chapter focusing specifically on studies of memory with MEG. There are sections with chapters that describe source localization issues, the use of beamformers and dipole source methods, as well as phase-based analyses, and a step-by-step guide to using dipoles for epilepsy spike analyses. The book ends with a section describing new innovations in MEG systems, namely an on-line real-time MEG data acquisition system, novel applications for MEG research, and a proposal for a helium re-circulation system. With such breadth of topics, there will be a chapter that is of interest to every MEG researcher or clinician.

The first volume on clinical magnetoencephalography and magnetic source imaging, measuring the magnetic fields generated by neuronal activity in the brain.

Fifty Years of Magnetoencephalography celebrates the first half century of research in and clinical applications of magnetoencephalography (MEG). It catalogs and documents its evolution as a means of imaging the ongoing activity of the brain and the activation of particular neuronal networks within it that mediate sensory motor and higher functions like language. The volume's first section looks at the discovery of MEG and its first tentative applications by three of its founders. The following sections detail the rapid progress in the development of the instrumentation necessary for recording noninvasively the magnetic signals on the head that are associated with the brain activity; improvements in the techniques for analyzing the magnetic signals and reconstructing, on their basis, the functional images of brain activity; and improvements in our understanding of the nature and significance of those signals. Subsequent sections of the book detail the main clinical applications of MEG in localizing brain areas that contain sources of epileptiform activity and areas encompassing parts of functional networks essential for motor and sensory function as well as for language that have become an essential part of planning for brain surgery in many epilepsy and tumor surgery centers around the world. In addition, several chapters describe the most current efforts aiming at expanding the utility of MEG in clinical diagnosis and theoretical research.

Magnetoencephalography (MEG) is an invaluable functional brain imaging technique that provides direct, real-time monitoring of neuronal activity necessary for gaining insight into dynamic cortical networks. Our intentions with this book are to cover the richness and transdisciplinary nature of the MEG field, make it more accessible to newcomers and experienced researchers and to stimulate growth in the MEG area. The book presents a comprehensive overview of MEG basics and the latest developments in methodological, empirical and clinical research, directed toward master and doctoral students, as well as researchers. There are three levels of contributions: 1) tutorials on instrumentation, measurements, modeling, and experimental design; 2) topical reviews providing extensive coverage of relevant research topics; and 3) short contributions on open, challenging issues, future developments and novel applications. The topics range from neuromagnetic measurements, signal processing and source localization techniques to dynamic functional networks underlying perception and cognition in both health and disease. Topical reviews cover, among others: development on SQUID-based and novel sensors, multi-modal integration (low field MRI and MEG; EEG and fMRI), Bayesian approaches to multi-modal integration, direct neuronal imaging, novel noise reduction methods, source-space functional analysis, decoding of brain states, dynamic brain connectivity, sensory-motor integration, MEG studies on perception and cognition, thalamocortical oscillations, fetal and neonatal MEG, pediatric MEG studies, cognitive development, clinical applications of MEG in epilepsy, pre-surgical mapping, stroke, schizophrenia, stuttering, traumatic brain injury, post-traumatic stress disorder, depression, autism, aging and neurodegeneration, MEG applications in cognitive neuropharmacology and an overview of the major open-source analysis tools.

The leading reference on electroencephalography since 1982, Niedermeyer's Electroencephalography is now in its thoroughly updated Sixth Edition. An international group of experts provides comprehensive coverage of the neurophysiologic and technical aspects of EEG, evoked potentials, and magnetoencephalography, as well as the clinical applications of these studies in neonates, infants, children, adults, and older adults. This edition's new lead editor, Donald Schomer, MD, has updated the technical information and added a major new chapter on artifacts. Other highlights include complete coverage of EEG in the intensive care unit and new chapters on integrating other recording devices with EEG; transcranial electrical and magnetic stimulation; EEG/TMS in evaluation of cognitive and mood disorders; and sleep in premature infants, children and adolescents, and the elderly. A companion website includes fully searchable text and image bank.

Biomagnetism involves the investigation of bioelectric processes as reflected by their accompanying magnetic fields. These processes can be monitored in the brain, heart, peripheral nerve or gastrointestinal tract. SQUID technology can also be used for biosusceptometry in lung, liver and intestines. Biomagnetism also includes theoretical issues as encountered in the inverse problem, modelling, fundamentals, physics and mathematics of the method, technical applications and instrumentation, as well as future aspects.