Clinical Biomechanics And Its Implications On Diabetic Foot

This book presents essential information on biomechanical features of the diabetic foot, which could help to minimize the risk of future diabetic foot problems. India has recently been classified as the ‘diabetic capital’ of the world. Type 2 diabetes mellitus has become a serious concern for Indian society, where the prevalence rate is increasing exponentially. Similarly, the comorbidities and foot complications of type 2 diabetes mellitus are worsening day by day. Of all complications, diabetes peripheral neuropathy is the most common, and leads to foot deformities, pain, altered sensation, loss of foot arch, etc. The ultimate fate can even be gangrene and amputation. Accordingly, foot complications of diabetes represent a pressing medical issue. Sharing insights into diabetic foot syndrome, its causative factors, prevention and management, this book offers a valuable resource for medical and paramedical students, researchers, podiatrists, surgeons, and physicians alike.

The Science, Etiology and Mechanobiology of Diabetes and Its Complications presents the most comprehensive synthesis of contemporary global research on diabetes, covering a novel and unique mechanobiological perspective – addressing prevention, management and treatment of tissue, organ and body system damage associated with diabetes and its complications. The book provides a unique approach to communicating diabetes-associated symptoms and opens avenues for development of novel therapeutic and preventive methods. It offers descriptive pathophysiology of diabetes and its complications with great emphasis on mechanobiology. Content coverage also includes management of tissue, organ and body system damage caused by chronic hyperglycemia. Biologists, life scientists, physicians, pharmacists, biomedical engineers, medical physicists, biomathematicians and computer scientists who are interested in the state-of-science and current challenges in the mechanobiology of diabetes should find this book very useful. Likewise, medical researchers in fields such as endocrinology, cardiovascular medicine, oncology, obesity, the immune system, inflammation and wound care and others who wish to be updated about the latest achievements in this exciting arena of research will find that information here. Covers the state-of-knowledge in diabetes research from a mechanobiological perspective, including cell death and (neural, connective, adipose, vascular, renal etc.) tissue damage cascades and healing processes Describes state-of-the-art technology in prevention, diagnosis, prognosis and treatment of tissue, organ and body system damage caused by chronic hyperglycemia and diabetes Explores emerging research directions and future technology trends in the field of diabetes prevention and care, including common complications of diabetes (foot ulcers and amputation, peripheral neuropathy, retinal damage, renal damage, vascular and cardiac damage, connective tissue damage etc.) at the early stage of research and development in academia and industry

This book discusses essential aspects of diabetic foot ulcers, including evidence-based information on its pathogenesis and pathophysiology, as well as the molecular mechanisms and biomechanics of the diabetic foot. It also highlights the need for a multidisciplinary team to be involved in the management of diabetic patients with foot ulcers, and describes available and future tools for evaluating patients who are at risk. Exploring the main current therapies as well as the latest developments, future directions and potential new treatments, such as growth factors, stem cell therapy, alternative medicine and nanotechnology, the book is a valuable resource for clinicians and medical graduates but will also appeal to researchers working in the field.

Since the publication of the third edition of The Foot in Diabetes, there have been important developments in the field of diabetic foot care and its scientific basis, including: The introduction of new technologies such as vacuum therapy, new casting techniques, the use of hormones and growth factors in wound healing; Advances in the understanding of the biomechanics of foot problems; Increased problems with multidrug-resistant organisms; The introduction of new international guidelines for the management of foot infections; Significant progress in the use of cytokines, metalloproteinase inhibitors, stem cells and gene therapy in wound healing. This fourth edition of this popular title maintains the strengths of earlier editions, with a strong emphasis on practical applications and management. All the chapters have been fully revised and updated, with new chapters introduced to cover the topics listed above. This book features more international contributors, giving it more global relevance than before, and for the first time it includes colour plates. With its focus on practically oriented advice, this book is essential reading for all members of the diabetes specialist team including diabetologists, podiatrists, specialist nurses, general practitioners, surgeons and clinical researchers.

Fully revised and updated edition of this popular book, addressing all issues concerning the diabetic foot, one of the most prevalent problems in diabetes, with a strong emphasis on practical aspects of delivering care.

​Public and political concern about the increasing prevalence of diabetes has prompted major concern about treatment of patients with the condition. Foot complications are some of the commonest causes of hospitalisation of people with diabetes and if not treated well often lead to amputation. There is evidence that 85% of these amputations can be prevented by better understanding of the problem and by multi-disciplinary teams working more effectively together. This has been recognised and NICE have recently published guidelines on diabetic foot complications as have Diabetes UK and NHS Diabetes. These have been successful in raising awareness of the problem but the local multi-disciplinary teams need clear practical advice on how to manage the foot in diabetes and deliver high quality care. With the current interest in improving outcomes for patients with foot complications this is an ideal time to make a practical evidence-based handbook available. This book will provide clear practical guidelines on how to manage all aspects of the foot in diabetes as well as an in-depth analysis of the most recent evidence. The book will be based on care pathways with algorithms for each section so it would be of practical value in any clinic in primary or secondary care. It will appeal to a wide range of health care professionals treating people with diabetes: vascular surgeons and trainees, orthopaedic surgeons, diabetes specialist nurses, podiatrists and tissue viability nurses.​

This book provides a clear and integrated guide to the diagnostic pathways and therapeutic options available for the treatment of diabetic foot syndrome. The link between the location of the lesion and its potential causes are discussed in relation to its diagnosis, biomechanics, treatment and prognosis. Chapters covering interdigital lesions, the lateral side of the foot, torsion of the hallux, and the charcot foot are included. Diabetic Foot Syndrome: From Entity to Therapy aims to facilitate interdisciplinary understanding and is relevant to endocrinologists, as well as vascular and orthopedic surgeons.