Clinical Research Made Easy

This new edition provides clinicians and trainees with guidance on the latest clinical research techniques and publishing in medical literature. Divided into six sections, the book begins with an overview of research and evidence-based medicine, then discusses the strengths and limitations of specific research designs including randomised controlled trials, cohort studies, case control studies and much more. The following sections cover reporting guidelines, writing a good research paper, sample size calculations, subgroup analyses and associated topics such as research ethics and patient consent. The second edition has been fully revised and expanded and includes new advanced content. Clinical images and figures further enhance the comprehensive text. Key points New edition providing guidance on latest clinical research techniques and publishing in medical literature Fully revised and expanded content with new advanced topics Internationally recognised author team Previous edition (9788184488906) published in 2010

Designing Clinical Research sets the standard for providing a practical guide to planning, tabulating, formulating, and implementing clinical research, with an easy-to-read, uncomplicated presentation. This edition incorporates current research methodology—including molecular and genetic clinical research—and offers an updated syllabus for conducting a clinical research workshop. Emphasis is on common sense as the main ingredient of good science. The book explains how to choose well-focused research questions and details the steps through all the elements of study design, data collection, quality assurance, and basic grant-writing. All chapters have been thoroughly revised, updated, and made more user-friendly.

A Practical Guide to Managing Clinical Trials is a basic, comprehensive guide to conducting clinical trials. Designed for individuals working in research site operations, this user-friendly reference guides the reader through each step of the clinical trial process from site selection, to site set-up, subject recruitment, study visits, and to study close-out. Topics include staff roles/responsibilities/training, budget and contract review and management, subject study visits, data and document management, event reporting, research ethics, audits and inspections, consent processes, IRB, FDA regulations, and good clinical practices. Each chapter concludes with a review of key points and knowledge application. Unique to this book is "A View from India," a chapter-by-chapter comparison of clinical trial practices in India versus the U.S. Throughout the book and in Chapter 10, readers will glimpse some of the challenges and opportunities in the emerging and growing market of Indian clinical trials.

Clinical Evidence Made Easy will give those working in healthcare the tools to understand the information available to them from clinical data sources, which can otherwise be hard to decipher.

Principles of Research Methodology: A Guide for Clinical Investigators is the definitive, comprehensive guide to understanding and performing clinical research. Designed for medical students, physicians, basic scientists involved in translational research, and other health professionals, this indispensable reference also addresses the unique challenges and demands of clinical research and offers clear guidance in becoming a more successful member of a medical research team and critical reader of the medical research literature. The book covers the entire research process, beginning with the conception of the research problem to publication of findings. Principles of Research Methodology: A Guide for Clinical Investigators comprehensively and concisely presents concepts in a manner that is relevant and engaging to read. The text combines theory and practical application to familiarize the reader with the logic of research design and hypothesis construction, the importance of research planning, the ethical basis of human subjects research, the basics of writing a clinical research protocol and scientific paper, the logic and techniques of data generation and management, and the fundamentals and implications of various sampling techniques and alternative statistical methodologies. Organized in thirteen easy to read chapters, the text emphasizes the importance of clearly-defined research questions and well-constructed hypothesis (reinforced throughout the various chapters) for informing methods and in guiding data interpretation. Written by prominent medical scientists and methodologists who have extensive personal experience in biomedical investigation and in teaching key aspects of research methodology to medical students, physicians and other health professionals, the authors expertly integrate theory with examples and employ language that is clear and useful for a general medical audience. A major contribution to the methodology literature, Principles of Research Methodology: A Guide for Clinical Investigators is an authoritative resource for all individuals who perform research, plan to perform it, or wish to understand it better.

Clinical Evidence Made Easy is a concise and accessible introduction for any healthcare professional looking to understand clinical evidence and data sources. Clinical Evidence Made Easy scores maximum 100 and 5 stars on Doody's (Sept 2014)! Here's what the reviewer said: "The authors present the concepts in a unique and simple way that is easy to read and understand." From other reviews: "The chapters are succinct. The text is simple and easy to follow........ I really like this text. The title says it all – Clinical Evidence Made Easy" Ulster Medical Journal "...the book will be useful for anyone who is interested in evidence based practice and who wants to be able to read published research papers and to pose appropriate questions of them." Nursing Times As clinical evidence becomes increasingly important in healthcare it is vital that healthcare professionals can read, analyse and understand the clinical data being presented. This book will equip the reader with the core skills and knowledge to make sense of the clinical evidence, without over-burdening them with information and jargon. Building on the success of the other ‘Made Easy’ books (Medical Statistics Made Easy, Healthcare Economics Made Easy, Practice Accounts Made Easy), this is a book for non-specialists who need knowledge of the key tools and techniques so they can understand the clinical data, but who have no need to become experts in the subject. Clinical Evidence Made Easy will enable healthcare workers in all fields to understand and implement the results from clinical trials, clinical journals and other data sources with confidence.

This classic reference, now updated with the newest applications and results, addresses the fundamentals of such trials based on sound scientific methodology, statistical principles, and years of accumulated experience by the three authors.