Commercializing Nanotechnology For Medicine

With recent developments in the fields of drug delivery and medical imaging, nanotechnology is rapidly moving out of the lab, into the commercialization phase. During the economic downturn, nanotech has remained a growth area, but research funding has increasingly been linked with commercialization, and academics have turned to the opportunities presented by startup launches and the interest venture capital has been taking in nanomedicine. Chan and Das can both boast the combination of academic backgrounds and successful commerial ventures, and have written this book to provide a both a routemap to business success and a toolkit for academics and researchers seeking to leverage research funding and venture capital. With a scientific rigor missing from many ‘nanobusiness’ books, they describe the current trends in nanomedicine at universities and examine how their developments and discoveries are being translated into real-world products that are expected to have great impact in health care. They discuss nanotechnology-based drug carriers and diagnostics, the value chain for nanomedicine businesses, the intellectual property landscape, and strategies for the commercialization of Nanomedicine products. There is currently tremendous interest and growth in the funding of Nanomedicine-based projects, number of start-up companies in the field, and intellectual properties filed. However, this is the first book-length study of the interface between nanomedicine and the commercial world. Chan and Das provide a much needed guide for the entrepreneurial scientist and entrepreneur interested in investing in emerging nanotechnologies for medicine. Chan and Das share their experience of successfully bridging the academic and commercial worlds, providing both academics and entrepreneurs with the toolkit they need to identify research developments with commercial potential and launch and run a successful startup. Readers will gain an understanding of the trends in the emerging technologies of nanomedicine, the regulatory environment, and the business developments that have caused commentators to describe nanotechnology as ‘the new industrial revolution’. Academics and Researchers will learn how to harness research funding and venture capital for the more rapid development of their research work. Case studies provide real world examples of the commercialization of nanomedicine.

The authors of this book address all individuals approaching the study of nanomedicine for the first time ever, as well as those already profitably working in the field either as scientists, doctors, lawyers, or entrepreneurs. Teeming with accurate, up-to-date, and enjoyable content, the book describes some enlightening facts and figures pertaining to the growing field of nanomedicine. Open problems and potentialities are identified and discussed, offering a series of forecasts regarding its global impact on healthcare systems in the coming two decades. This introduction is followed by three different sections: (a) one purely scientific, which delves deep into areas as diverse as proteomics or delivery systems for nanodrugs, demonstrating how nanotechnology is reshaping the way diagnosis and treatment of diseases are made; (b) one focused on the ethical challenges that governments and companies are facing or will have to face in order to protect patients’ rights; and (c) one entirely dedicated to the legal and entrepreneurial issues that are driving this entire medical revolution. In the pages of this lucidly written book, scientists and managers will certainly find the need-to-have tool on their desk to thrive and succeed in the commercialization of nanomedicine.

Global advances in medicine, food, water, energy, microelectronics, communications, defense, and other important sectors of the economy are increasingly driven by discoveries in nanoscience and the development of nanotechnologies. Engaging the nanoscience and technology community in the crafting of national priorities, developing novel approaches for translating fundamental discovery to a technology readiness level appropriate for venture/industry funding, increasing domestic student interest in nanoscience to expand the workforce pipeline, and exploring new ways of coordinating the work of the National Nanotechnology Initiative (NNI) are all imperatives if the United States is to fully reap the societal benefits of nanotechnology. A Quadrennial Review of the National Nanotechnology Initiative provides a framework for a redesign of the NNI and its coordination with the goal of achieving a U.S. resurgence in nanotechnology. This report makes recommendations to improve the value of the NNI's research and development strategy and portfolio to the economic prosperity and national security of the United States.

Commercializing Nanotechnology: A Roadmap to Taking Nanoproducts from Laboratory to Market provides a step-by-step roadmap for taking the results of laboratory research on nanotechnology and nanomaterials and developing them into successful and profitable commercial ventures. It details the methodology, techniques, and pathways for technology-readiness assessment, testing protocols, and commercialization, and it discusses manufacturing techniques, including their limitations and challenges. Provides methodology, techniques, and pathways for technology-readiness assessment, testing protocols, and commercialization Offers general direction and assistance to researchers Describes manufacturing techniques, including their limitations and challenges Discusses intellectual property protection Provides details on market opportunities This book is aimed at scientists and engineers, including chemists, physicists, economists, medical practitioners, managers, marketers, traders, investors, and entrepreneurs in the fields of nanoscience, nanomedicine, nanoengineering, and nanomanufacturing.

This book covers diverse areas in which nanoscience and nanotechnology have led to significant technological advances and practical applications, with special emphasis on novel types of nanomaterials and their applicability into a new generation of nano- and micro-devices. Different nanomaterials are reviewed with a focus on several practical application areas and their commercial utilization. Production technologies of nanomaterials are presented as one of the challenges today. Sectors where nanotechnology has already significantly contributed are presented, along with specific nanotechnology solutions: energy related sectors, NEMS/MEMS, micro power generators, spintronics and healthcare. The basic properties and applications of nanostructured thermoelectric materials, ferroelectric and piezoelectric nanomaterials are reviewed. Examples of several developed thin-film thermogenerators are shown. A review of existing solutions and developing challenges are given regarding sustainable energy production, photovoltaics, solar cells, hydrogen economy and improved classes of batteries as contributions to green products and circular economy. Novel, highly promising areas in nanotechnology, are shown, such as voltage-driven nano-spintronics. Recent advances in friction characterisation at the nano level are described. Several proven nanomaterials have been reviewed pertaining to biomedicine. The use of nanomaterials in ophthalmology and cosmetic industry are reviewed, and the potential for silver nanoparticles and iron-based nanomaterials in biomedicine, also with recognised challenges and possible threats of non-controlled use of nanomaterials. This work is the result of joint efforts of different companies, academic, and research institutions participating in WIMB Tempus project, 543898-TEMPUS-1-2013-1-ES-TEMPUS-JPHES, "Development of Sustainable Interrelations between Education, Research and Innovation at WBC Universities in Nanotechnologies and Advanced Materials where Innovation Means Business", co-funded by the Tempus Programme of the European Union.

Nanotechnology is a multidisciplinary field that is revolutionizing the way we detect and treat damage to the human body. Nanomedicine applies nanotechnology to highly specific medical interventions for the prevention, diagnosis, and treatment of diseases. They are increasingly being used to overcome biological barriers in the body to improve the way we deliver compounds to specific tissues and organs. In particular, nanomedicines have been shown to be beneficial for stabilizing therapeutic compounds, overcoming obstacles to cellular and tissue uptake, and improving biodistribution of compounds to target sites in vivo. Nanomedicines have demonstrated significant therapeutic advantages for a multitude of biomedical applications, however the clinical translation of these nanotechnology platforms has not progressed as quickly as the plethora of positive results would have suggested. Understanding the advances in nanomedicine to date and the challenges that still need to be overcome, will allow future research to improve on existing platforms and to address the current translational and regulatory limitations. This eBook “Advances and Challenges in Nanomedicine” has brought together experts in the fields of nanomedicine, nanotechnology, nanotoxicology, pharmaceutics, manufacturing, and translation to discuss the application of nanotechnology to drug delivery. This information is presented as original research, opinion, perspective, and review articles. The goal of this eBook is to generate collaborative discussion on the current status, general trends, challenges, strategies, and future direction of pharmaceutical nanotechnology, as well as highlight current and emerging nanoparticulate platforms with potential medical applications.

A fascinating and informative look at state-of-the-art nanotechnology research, worldwide, and its vast commercial potential Nanotechnology Commercialization: Manufacturing Processes and Products presents a detailed look at the state of the art in nanotechnology and explores key issues that must still be addressed in order to successfully commercialize that vital technology. Written by a team of distinguished experts in the field, it covers a range of applications notably: military, space, and commercial transport applications, as well as applications for missiles, aircraft, aerospace, and commercial transport systems. The drive to advance the frontiers of nanotechnology has become a major global initiative with profound economic, military, and environmental implications. Nanotechnology has tremendous commercial and economic implications with a projected $ 1.2 trillion-dollar global market. This book describes current research in the field and details its commercial potential—from work bench to market. Examines the state of the art in nanotechnology and explores key issues surrounding its commercialization Takes a real-world approach, with chapters written from a practical viewpoint, detailing the latest research and considering its potential commercial and defense applications Presents the current research and proposed applications of nanotechnology in such a way as to stimulate further research and development of new applications Written by an all-star team of experts, including pioneer patent-holders and award-winning researchers in nanotechnology The major challenge currently faced by researchers in nanotechnology is successfully transitioning laboratory research into viable commercial products for the 21st century. Written for professionals across an array of research and engineering disciplines, Nanotechnology Commercialization: Manufacturing Processes and Products does much to help them bridge the gap between lab and marketplace.

This book provides a comprehensive overview of the recent trends in various Nanotechnology-based therapeutics and challenges associated with its development. Nanobiotechnology is an interdisciplinary research that has wide applications in the various fields of biomedical research. The book discusses the various facets of the application of Nanotechnology in drug delivery, clinical diagnostics, Nanomedicine and treatment of infectious and chronic diseases. The book also highlights the recent advancements on important devices and applications that are based on Nanotechnology in medicine and brief the regulatory and ethical issues related to nanomedical devices. It also reviews the toxicological profile of various nanomaterials and emphasizes the need for safe nanomaterials for clinical use. Finally, the book discusses the recent developments of potential commercial applications of Nanotechnology.