Congenital Vascular Malformations

This book is a superbly illustrated guide to the diagnosis and treatment of congenital vascular malformations (CVMs) that will enable the reader to avoid the serious pitfalls that may arise when caring for patients with this rare and complex group of lesions. After discussion of pathogenesis, classification, and differential diagnosis from vascular tumors, the clinical features of CVMs are described and illustrated, covering both the various forms (venous, arteriovenous, lymphatic, capillary, and mixed) and presentations at different anatomic sites. The current role of CT, MRI, scintigraphy, and angiography in diagnostic evaluation is explained, and treatment options, including conservative treatment, are then considered in detail. The discussion of endovascular treatment, or embolo-sclerotherapy, includes instruction on patient selection, embolic and sclerosing materials, access to the target lesion, site-specific variations in treatment strategy, and complications and their management. Indications for and performance of surgical/excisional therapy and laser therapy are also fully considered.

This new book on vascular malformations brings together international experts to present advances and discuss controversies in the multidisciplinary management of patients with congenital vascular malformations. Major advances in recent years in medical genetics, and tremendous progress in the fields of imaging and minimally invasive percutaneous interventions have revolutionized both evaluation and management of vascular malformations. The six major parts of this state of the art book ensure that the reader has the most up to date valuable clinical information to ensure the delivery of world class clinical practice. Beautifully illustrated with color line drawings, numerous photographs and informative tables, the advances and controversies of the full spectrum of vascular malformations are presented in 90 definitive chapters. Vascular Malformations brings new information and unparalleled insights to vascular specialists and physicians, trainees and allied health professionals who participate in the care of patients with vascular malformations, either in a private practice setting or at a major institution in an interdisciplinary vascular center.

The field of vascular anomalies has grown rapidly in last 25 years. Molecular genetics has led to discovery of genes that cause vascular anomalies. Interventional radiology has become a major contributor to accurate diagnosis and management of previously untreatable disorders. New pharmacologic therapies are under investigation and surgical protocols have been established. Vascular Anomalies: Hemangiomas and Malformations is a comprehensive and interdisciplinary textbook ideal for dermatologists, interventional radiologists, surgical specialists, ophthalmologists, pathologists, geneticists, pediatricians, hematologic-oncologists, and vascular biologists. With a central motif of the biologic dichotomy of vascular tumors and vascular malformations, this book is organized into chapters which address clinical presentation, diagnostic imaging, molecular genetics, pathogenesis, histopathology, and management of vascular anomalies. Generous, full-color images compliment this extensive volume written by three colleagues and their teammates from Children's Hospital Boston and Harvard Medical School, with leading specialists from other centers.

This issue of Otolaryngologic Clinics, guest edited by Drs. Teresa M. O and Milton Waner, is devoted to Congenital Vascular Lesions of the Head and Neck. Articles in this issue include: Classification and Pathology of Congenital Vascular Anomalies of the Head and Neck; Etiology and Genetics of Congenital Vascular Lesions; Radiological Evaluation of Congenital Vascular Anomalies; Congenital Vascular Tumors; The Role of Surgery in the Management of Infantile Hemangiomas; The Management of Airway Infantile Hemangiomas; Multidisciplinary Approach to the Management of Lymphatic Malformations of the Head and Neck; New Frontiers in Our Understanding of Lymphatic Malformations of the Head and Neck; Venous Malformations of the Head and Neck; Capillary Malformations of the Head and Neck; Arteriovenous Malformations of the Head and Neck; The Management of Vascular Malformations of the Airway; Role of Neurophysiological Monitoring in the Surgical Management of Congenital Vascular Lesions of the Head and Neck; Acquired Vascular Tumors of the Head and Neck; Orthognathic and Dental Considerations; Hereditary Hemorrhagic Telangiectasia; and Psychosocial Impact of Living with a Facial Vascular Lesion.

Since the first edition of this book was published, much new knowledge has been gained on hemangiomas and vascular malformations. This revised and updated second edition, written by worldwide leaders in the field, fully reflects this progress. Important improvements in the treatment of hemangiomas are reviewed, including the use of beta-blockers and other medical therapies as well as advances in interventional treatments and the treatment of hemangiomas in specific locations. Vascular malformations are being investigated with increasing frequency all over the world and new challenges are emerging regarding both diagnosis and treatment. This edition considers the current role of the full range of diagnostic imaging techniques –magnetic resonance imaging, computed tomography, nuclear medicine techniques, angiography, and phlebography. The various treatment options, including laser, interventional radiological, and surgical techniques, are then presented in detail. A further individual section is devoted to the study and treatment of lymphatic malformations and dysplasias, and a series of chapters also focus on problems in the treatment of malformations in particular locations, including the thorax and viscera. This book, in atlas format, is exceptional in providing clinically relevant information on the diagnosis and treatment of both hemangiomas and vascular malformations. It will appeal to all professionals who encounter these conditions in their daily clinical practice.

This issue of Otolaryngologic Clinics, guest edited by Drs. Teresa M. O and Milton Waner, is devoted to Congenital Vascular Lesions of the Head and Neck. Articles in this issue include: Classification and Pathology of Congenital Vascular Anomalies of the Head and Neck; Etiology and Genetics of Congenital Vascular Lesions; Radiological Evaluation of Congenital Vascular Anomalies; Congenital Vascular Tumors; The Role of Surgery in the Management of Infantile Hemangiomas; The Management of Airway Infantile Hemangiomas; Multidisciplinary Approach to the Management of Lymphatic Malformations of the Head and Neck; New Frontiers in Our Understanding of Lymphatic Malformations of the Head and Neck; Venous Malformations of the Head and Neck; Capillary Malformations of the Head and Neck; Arteriovenous Malformations of the Head and Neck; The Management of Vascular Malformations of the Airway; Role of Neurophysiological Monitoring in the Surgical Management of Congenital Vascular Lesions of the Head and Neck; Acquired Vascular Tumors of the Head and Neck; Orthognathic and Dental Considerations; Hereditary Hemorrhagic Telangiectasia; and Psychosocial Impact of Living with a Facial Vascular Lesion.

The book covers all aspects of vascular malformations including classification, embryology, genetics, clinical approach, investigations, management, controversies and key points to remember. Chapters cover recent changes in detail in various aspects, such as classification, genetic decoding, minimal intervention, selective approach and investigations for different types. It offers clear guidance on diagnostic protocol and surgical decision making with changing scenario leading to evolving endovascular and radiological interventions. The book is useful for vascular surgeon, pediatric surgeon, general surgeon, plastic surgeon and intervention radiologist as well as clinical research scholars, surgical oncologists and radiologists.

A consummate classic with a fresh approach to pediatric dermatology Children ́s skin is different. Maturation affects the epidermal barrier, the cutaneous microbiome, adnexal structures, vasculature, and transcutaneous absorption of drugs. The immature skin is more susceptible to pathogens and environmental disruption. Many genetic disorders are either present at birth or manifest early in childhood. Skin diseases thus present differently in children than in adults. Pediatric dermatology has seen significant advances over the last decade, particularly in the field of molecular genetics research, which has furthered our understanding of the pathogenesis of many skin diseases and the development of new approaches to treatment. This fourth edition of the Harper classic provides state-of-the-art information on all aspects of skin disease in children. It covers the diagnosis and treatment of all conditions - both common and rare - with a consistently evidence-based approach. Existing content has been refreshed and fully updated to reflect emerging thinking and to incorporate the latest in research and clinical data - especially at the genetic level. This new fourth edition includes: Greater focus on the genetics behind skin disease, including new genes/genodermatoses, progress in genetic analysis, and stem cell transplants Increased coverage of lasers and other technologies used to treat skin disease More summary tables, learning points, tables of differential diagnosis, and clinical algorithms for diagnosis and management Additional online features, including patient information links and multiple choice questions Harper's Textbook of Pediatric Dermatology delivers crucial clinical insights and up-to-date research information that spans the breadth of the field. As the most comprehensive reference book on this subject available, this revised fourth edition will support and guide the daily practice of both dermatologists and pediatricians across the world.