Coronavirus Disease

In December 2019, the world witnessed the occurrence of a new coronavirus to humanity. The disease spread quickly and became known as a pandemic globally, affecting both society and the health care system, both the elderly and young groups of people, and both the men’s and women’s groups. It was a universal challenge that immediately caused a surge in scientific research. Be a part of a world rising in fighting against the pandemic, the Coronavirus Disease - COVID-19 was depicted in the early days of the pandemic, but updated by more than 200 scientists and clinicians to include many facets of this new infectious pandemic, including i, characteristics, ecology, and evolution of coronaviruses; ii, epidemiology, genetics, and pathogenesis (immune responses and oxidative stress) of the disease; iii, diagnosis, prognosis, and clinical manifestations of the disease in pediatrics, geriatrics, pregnant women, and neonates; iv, challenges of co-occurring the disease with tropical infections, cardiovascular diseases, hypertension, and cancer and to the settings of dentistry, hematology, ophthalmology, and pharmacy; v, transmission, prevention, and potential treatments, ranging from supportive ventilator support and nutrition therapy to potential virus- and host-based therapies, immune-based therapies, photobiomodulation, antiviral photodynamic therapy, and vaccines; vi, the resulting consequences on social lives, mental health, education, tourism industry and economy; and vii, multimodal approaches to solve the problem by bioinformatic methods, innovation and ingenuity, globalization, social and scientific networking, interdisciplinary approaches, and art integration. We are approaching December 2020 and the still presence of COVID-19, asking us to call it COVID (without 19).

This book provides a comprehensive overview of recent novel coronavirus (SARS-CoV-2) infection, their biology and associated challenges for their treatment and prevention of novel Coronavirus Disease 2019 (COVID-19). Discussing various aspects of COVID-19 infection, including global epidemiology, genome organization, immunopathogenesis, transmission cycle, diagnosis, treatment, prevention, and control strategies, it highlights host-pathogen interactions, host immune response, and pathogen immune invasion strategies toward developing an immune intervention or preventive vaccine for COVID-19. An understanding of the topics covered in the book is imperative in the context of designing strategies to protect the human race from further losses and harm due to SARS-CoV-2 infection causing COVID-19.

CORONAVIRUS DISEASE 2019 (COVID-19) CORONAVIRUS DISEASE 2019 (COVID-19) Provides comprehensive coverage of all key aspects of COVID-19, including: etiology, diagnosis, symptomatology, management, and treatment Coronavirus Disease 2019 (COVID-19): A Clinical Guide provides healthcare professionals at all levels with up-to-date knowledge about the clinical, epidemiological, genomic, virological, and radiologic features of COVID-19. Consolidating multiple systematic reviews and meta-analyses into a single volume, this comprehensive textbook also addresses health policies, mass casualty planning, healthcare worker safety, economic impact, lessons for future outbreaks, and other para-clinical and social aspects of the COVID-19 pandemic. The text presents a thorough summary and critical analysis of COVID-19 based on an exhaustive review of recently published literature and data. Topics include the virologic characteristics of SARS-CoV-2, pulmonary and extrapulmonary manifestations and consequences of COVID-19, prevention and transmission control, the pandemic’s indirect impact to the care and management of other diseases, passive immunotherapy and its implications, diagnostic and treatment approaches for critically ill patients, and more. Edited by leading ­practitioners at the forefront of COVID-19 research, this invaluable resource: Integrates clinical, radiological, and epidemiological data and discussion of prevention, diagnosis, and treatment Reviews the epidemiology, mechanisms of action, manifestations, and management of cardiovascular, neurological, and pulmonary diseases associated with COVID-19 Covers diagnostic technologies, includes radiologic imaging, and RT-PCR testing Explores therapeutic approaches for managing a variety of complications Discusses post-vaccination symptom management and implications of immunization Addresses COVID-19 in pediatrics, in cancer patients, and in patients with lung disease, diabetes, ­hypertension, obesity, and other underlying conditions Coronavirus Disease 2019 (COVID-19): A Clinical Guide is an indispensable source of information for all clinicians, researchers, epidemiologists, nurses, radiologists, and healthcare managers working to address any aspect of the COVID-19 pandemic.

CONTENTS Chapter I A Review: General Outlook of Coronavirus and SARS-CoV-2……1 Chapter II Covid-19: Update Pathogenesis and Clinical Effects……………..19 Chapter III Epidemiology of Covid-19…………………………………………….29 Chapter IV Effect of ACEIs (Angiotensin-Converting Enzyme Inhibitors) and ARBs (Angiotensin II Receptor Blockers) on as Coronavirus Disease 2019 (Covid-19)…………………………………………41 Chapter V Covid-19 and Food Safety…………………………………………….49 Chapter VI “Covid-19” in the Framework of a Dystopian Element…………..59

This book includes recent research works on how business around the world affected by the time of COVID-19 pandemic. The impact of recent technological developments has had a tremendous impact on how we manage disasters. These developments have changed how countries and governments collect information. The COVID-19 pandemic has forced online service companies to maintain and build relationships with consumers when their world turns. Businesses are now facing tension between generating sales during a period of severe economic hardship and respect for threats to life and livelihoods that have changed consumer preferences.

Almost nine months since the first recorded case, the novel betacoronovirus; severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has now passed 18 million confirmed cases. The multi-disciplinary work of researchers worldwide has provided a far deeper understanding of COVID-19 pathogenesis, clinical treatment and outcomes, lethality, disease-spread dynamics, period of infectivity, containment interventions, as well as providing a wealth of relevant epidemiological data. With 27 vaccines currently undergoing human trials, and countries worldwide continuing to battle case numbers, or prepare for resurgences, the need for efficient, high-quality pipelines for peer-reviewed research remains as crucial as ever.

The book "Interaction of Coronavirus Disease 2019 with other Infectious and Systemic Diseases" elaborates on the pathogenesis, co-infection, and association of COVID-19 with other Infectious and Systemic Diseases. Moreover, this book explains pharmacological interventions, and therapeutic targets in COVID19. All chapters cover the different aspects of COVID-19. This book gives first-hand information on the co-infection, post-COVID effects, nanomedicine, and pharmacogenomics in COVID-19. The book offers comprehensive coverage of the most essential topics, including: Recent developments in COVID-19 pathogenesis and treatment Association of COVID-19 with Infectious diseases and Systemic Diseases COVID-19 and Co-infection Post-COVID and long-term COVID problems Nanomedicine and pharmacogenomics in COVID-19 While other books may touch on COVID-19 pathophysiology and treatment strategies. Unique aspect of this book is that it covers post COVID effects, and Interaction of Coronavirus Disease 2019 with other Infectious and Systemic Diseases.

COVID-19: Epidemiology, Biochemistry, and Diagnostics explains COVID-19 from multidisciplinary angles such as the evolution of SARS-COV, genetic techniques to study the virus, and diagnostic methodologies widely used in the global COVID-19 pandemic. The chapters in this book provide the reader with up-to-date literature about research on SARS-CoV-2 through three parts: I) Evolution and Entry of SARS-CoV-2 into the host II) Genetic Alteration and Structural Determination of SARS-CoV-2 Proteins III) Quantitative Analysis of SARS-CoV-2 for research and medical diagnosis Key Features: - 15 chapters on SAR-CoV-2 in a multidisciplinary context - Provides a comprehensive overview of SARS-CoV-2 evolution and genetics - Provides biochemical information about SARS-CoV-2 proteins and receptor targets (both structural and non-structural proteins) - Includes an overview of several methods of detecting SARS-CoV-2 virus particles (ELISA, PCR, Neutralizing Antibodies - Covers some critical diagnostic modalities for COVID-19 diagnosis - Provides bibliographic references for further reading Readers will understand the significance of phylogenetic analysis of coronaviruses, along with the pathogenesis of COVID-19 and related diseases such as SARS and MERS. Applications of biochemical technologies such as RT-PCR and CRISPR are also demonstrated in the text. This book is a comprehensive introduction to COVID-19 research for medical researchers, microbiologists and virologists. Students in academic programs in life sciences and medicine will also benefit from the information provided in the book.