Delay Differential Equations And Applications To Biology

This book discusses the numerical treatment of delay differential equations and their applications in bioscience. A wide range of delay differential equations are discussed with integer and fractional-order derivatives to demonstrate their richer mathematical framework compared to differential equations without memory for the analysis of dynamical systems. The book also provides interesting applications of delay differential equations in infectious diseases, including COVID-19. It will be valuable to mathematicians and specialists associated with mathematical biology, mathematical modelling, life sciences, immunology and infectious diseases.

This book discusses the numerical treatment of delay differential equations and their applications in bioscience. A wide range of delay differential equations are discussed with integer and fractional-order derivatives to demonstrate their richer mathematical framework compared to differential equations without memory for the analysis of dynamical systems. The book also provides interesting applications of delay differential equations in infectious diseases, including COVID-19. It will be valuable to mathematicians and specialists associated with mathematical biology, mathematical modelling, life sciences, immunology and infectious diseases.

This book is intended to be an introduction to Delay Differential Equations for upper level undergraduates or beginning graduate mathematics students who have a reasonable background in ordinary differential equations and who would like to get to the applications quickly. The author has used preliminary notes in teaching such a course at Arizona State University over the past two years. This book focuses on the key tools necessary to understand the applications literature involving delay equations and to construct and analyze mathematical models involving delay differential equations. The book begins with a survey of mathematical models involving delay equations.

In studying the dynamics of populations, whether of animals, plants or cells, it is crucial to allow for delays such as those due to gestation, maturation or transport. This book deals with a fundamental question in the analysis of the effects of delays, namely whether they affect the stability of steady states.

This volume is dedicated to the memory of Professor Stavros Busenberg of Harvey Mudd College, who contributed so greatly to this field during 25 years prior to his untimely death. It contains about 60 invited papers by leading researchers in the areas of dynamical systems, mathematical studies in ecology, epidemics, and physiology, and industrial mathematics. Anyone interested in these areas will find much of value in these contributions.

This book presents the proceedings from the International Conference held in Halifax, NS in July 1997. Funded by The Fields Institute and Le Centre de Recherches Mathématiques, the conference was held in honor of the retirement of Professors Lynn Erbe and Herb I. Freedman (University of Alberta). Featured topics include ordinary, partial, functional, and stochastic differential equations and their applications to biology, epidemiology, neurobiology, physiology and other related areas. The 41 papers included in this volume represent the recent work of leading researchers over a wide range of subjects, including bifurcation theory, chaos, stability theory, boundary value problems, persistence theory, neural networks, disease transmission, population dynamics, pattern formation and more. The text would be suitable for a graduate or advanced undergraduate course study in mathematical biology. Features: An overview of current developments in differential equations and mathematical biology. Authoritative contributions from over 60 leading worldwide researchers. Original, refereed contributions.

This book groups material that was used for the Marrakech 2002 School on Delay Di'erential Equations and Applications. The school was held from September 9-21 2002 at the Semlalia College of Sciences of the Cadi Ayyad University, Marrakech, Morocco. 47 participants and 15 instructors originating from 21 countries attended the school. Fin- cial limitations only allowed support for part of the people from Africa andAsiawhohadexpressedtheirinterestintheschoolandhadhopedto come. Theschoolwassupportedby'nancementsfromNATO-ASI(Nato advanced School), the International Centre of Pure and Applied Mat- matics (CIMPA, Nice, France) and Cadi Ayyad University. The activity of the school consisted in courses, plenary lectures (3) and communi- tions (9), from Monday through Friday, 8. 30 am to 6. 30 pm. Courses were divided into units of 45mn duration, taught by block of two units, with a short 5mn break between two units within a block, and a 25mn break between two blocks. The school was intended for mathematicians willing to acquire some familiarity with delay di'erential equations or enhance their knowledge on this subject. The aim was indeed to extend the basic set of knowledge, including ordinary di'erential equations and semilinearevolutionequations,suchasforexamplethedi'usion-reaction equations arising in morphogenesis or the Belouzov-Zhabotinsky ch- ical reaction, and the classic approach for the resolution of these eq- tions by perturbation, to equations having in addition terms involving past values of the solution.

This monograph provides a definitive overview of recent advances in the stability and oscillation of autonomous delay differential equations. Topics include linear and nonlinear delay and integrodifferential equations, which have potential applications to both biological and physical dynamic processes. Chapter 1 deals with an analysis of the dynamical characteristics of the delay logistic equation, and a number of techniques and results relating to stability, oscillation and comparison of scalar delay and integrodifferential equations are presented. Chapter 2 provides a tutorial-style introduction to the study of delay-induced Hopf bifurcation to periodicity and the related computations for the analysis of the stability of bifurcating periodic solutions. Chapter 3 is devoted to local analyses of nonlinear model systems and discusses many methods applicable to linear equations and their perturbations. Chapter 4 considers global convergence to equilibrium states of nonlinear systems, and includes oscillations of nonlinear systems about their equilibria. Qualitative analyses of both competitive and cooperative systems with time delays feature in both Chapters 3 and 4. Finally, Chapter 5 deals with recent developments in models of neutral differential equations and their applications to population dynamics. Each chapter concludes with a number of exercises and the overall exposition recommends this volume as a good supplementary text for graduate courses. For mathematicians whose work involves functional differential equations, and whose interest extends beyond the boundaries of linear stability analysis.