Design And Applications Of Theranostic Nanomedicines

Design and Applications of Theranostic Nanomedicines reviews the composition and design of various nanomedicines for theranostic applications, helping readers to make informed decisions when exploring novel treatments for disease. This book introduces readers to theranostic nanostructures as nanomedicines, beginning with a balanced look at the associated challenges, costs and benefits. The next section goes on to detail a range of different theranostic nanomedicines and their design, from nanodispersions and nanogels to exosomes and polymeric micelles. A variety of applications is covered, including in the treatment of pulmonary diseases, neurological disorders, cancers and more. The book also takes a look at the toxicological implications of nanotheranostics, an important aspect of any therapy or treatment. Design and Applications of Theranostic Nanomedicines provides a snapshot of the state-of-the-art, and will be of use to materials scientists, biomedical engineers and pharmaceutical scientists with an interest in nanotechnology and theranostics. Explores the challenges, costs, benefits and toxicological implications of nanotheranostics Reviews a range of nanomedicines and their design, including liposomes, nanohydrogels, nanocochleate and more Details a variety of applications, such as in drug delivery, neurological disorders, cardiovascular diseases and so on

This book discusses approaches based on multifunctional and targeted theranostic nanomedicines for improving diagnosis and drug delivery. It explores nanomedicines based on nanocarriers like liposomes, ethosomes, niosomes, polymeric nanoparticles, lipidic nanoparticles, metallic nanoparticles, micelles, dendrimers, quantum dots, carbon-based nanomaterials including carbon nanotubes, carbon dots, carbon quantum dots, graphene oxide, and fullerene. This book reviews designing, conjugation, optimization, formulation and development, and scale-up of multifunctional and targeted theranostic nanomedicines. It examines major challenges in developing nanomaterials that can be applied to nanomedicine with high biocompatibility and biodegradability for diagnostic and therapeutic purposes. Lastly, it addresses the most promising approaches at both commercialization and regulatory steps for bringing theranostic nanomedicine from research laboratories to clinics for patient use. ​

Design of Nanostructures for Theranostics Applications focuses on the theranostics applications of nanostructures. In particular, multifunctional nanoparticles for diagnostics and treatment of different diseases, including those relating to the blood-brain barrier, are discussed in detail. Chapters explore different type of nanostructures, covering design, fabrication, functionalization and optimization, helping readers obtain the desired properties. Written by a diverse range of international academics, this book is a valuable reference resource for those working in both nanoscience and the pharmaceutical industry. Explores how the design of a range of nanomaterials make them effective theranostic agents, including multifunctional core-shell nanostructures, mesoporous silica nanoparticles, and quantum dots Shows how nanomaterials are used effectively for a range of diseases, including breast cancer, prostate cancer and neurological disorders Assesses the pros and cons of using different nanomaterials for different types of treatment

This book highlights the recent advances in nanotheranostics from basic research to potential applications, and discusses the modular design and engineering of multiplex nanoparticles including gold nanostructures, luminescent nanoparticles, dendrimers and liposomes. Each chapter demonstrates multifunctional nanoparticles with topics covering targeting, imaging, delivery, diagnostics, and therapy as new modalities for cancer theranostics. This comprehensive book presents expert views on the latest developments in theranostic nanomedicine. It focuses on potential theranostic applications of multifunctional nanoparticles ranging from identifying noninvasively cancer cells by molecular detection, and visualizing in vivo drug delivery by means of contrast enhanced imaging, to destroying cancer cell s with minimal side effects via selective accumulation at tumor sites, and real-time monitoring therapeutic effectiveness. It also presents an interdisciplinary survey of nanotheranostics and as such is a valuable resource for researchers and students in related fields. Zhifei Dai is a Professor at the Department of Biomedical Engineering, College of Engineering, Peking University, China.

Multifunctional Theranostic Nanomedicines in Cancer focuses on new trends, applications, and the significance of novel multifunctional nanotheranostics in cancer imaging for diagnosis and treatment. Cancer nanotechnology offers new opportunities for cancer diagnosis and treatment. Multifunctional nanoparticles harboring various functions—including targeting, imaging, and therapy—have been intensively studied with the goal of overcoming the limitations of conventional cancer diagnosis and therapy. Thus theranostic nanomedicines have emerged in recent years to provide an efficient and safer alternative in cancer management. This book covers polymer-based therapies, lipid-based therapies, inorganic particle-based therapies, photo-related therapies, radiotherapies, chemotherapies, and surgeries. Multifunctional Theranostic Nanomedicines in Cancer offers an indispensable guide for researchers in academia, industry, and clinical settings; it is also ideal for postgraduate students; and formulation scientists working on cancer. Provides a comprehensive resource of recent scientific progress and novel applications of theranostic nanomedicines Discusses treatment options from a pharmaceutical sciences perspective Includes translational science and targeted CNS cancer treatment

This book is specifically designed to provide information about various nanocarriers currently developed under the emerging field of nanotheranostics for a sustained, controlled, and targeted co-delivery of diagnostic and therapeutic agents. Diverse theranostic applications of nanotechnology and their limitations are also addressed. It integrates nanobiotechnology with theranostic applications. The combined term nanotheranostics has diverse application particularly in chemotherapy and other infectious diseases.Among other topics addressed are antimicrobial resistance, targeting intra-cellular pathogens, viruses and bacteria, chemotherapy, cancer therapeutics, and inflammatory disorders. This interdisciplinary volume is essential for a diverse group of readers including nanotechnologists, microbiologists, biotechnologists, bioengineering and bioprocess industry.

Theranostic Bionanomaterials is an invaluable study of recent advances and trends in the development and application of functional bionanomaterials for theranostic applications. This book describes the design and characterization of nanomaterials which exhibit distinctive physical, chemical and biological properties and discusses how these functional nanomaterials enable the precise manipulation of architectural, physical and biochemical cell microenvironments in vitro. In addition, it covers how they can act as the carriers of diagnostic or therapeutic agents, thus providing new pathways or strategies for disease diagnosis and treatment. Specific chapters discuss protein delivery, drug delivery, tissue regeneration, bioimaging, biodetection, and much more. This book will be a critical resource for those involved in cutting-edge research in theranostics bionanomaterial. Focuses on nanofabrication methods of bionanomaterials Reviews the application of bionanomaterials, with a focus on drug delivery and diagnosis Describes the design and characterization of nanomaterials which exhibit distinctive physical, chemical and biological properties

This book covers a number of engineered nanotheranostics platforms and nanomedicines applications of FDA-approved medicines for early-stage diagnosis and treatment of cancer. The book focuses on (i) the basic design and bioengineering of safe medicines, (ii) physicochemical understanding of surface engineered medicines and their characteristics, (iii) various examples for site-specific bioimaging and multimode therapies, (iv) stimuli-responsive approaches for targeted drug delivery applications, (v) targeted therapeutics approaches for cancer cells or solid tumor ablations, (vi) targeted mechanisms of administrative biomedicines, (vii) impact of surface modification or engineering of biomedicines for site-selective tumor binding ability, and (vii) requirements for clinical trials and FDA approval. The content of this book appeal to readers who are interested in recent developments of FDA-approved cost-effective rapid cancer imaging and therapeutic platforms.