Diabetic Retinopathy

A well-illustrated and comprehensive analysis of the treatment of diabetic retinopathy, this book covers current treatment options and guidelines, whilst also providing a detailed discussion of emerging therapeutic targets. Existing therapeutic options are covered in depth, with a major focus on anti-vascular endothelial growth factor drugs and sustained release corticosteroids, including a review of trial results supporting current treatment guidelines. The use of agents off-label is also discussed. Controversial topics are discussed in detail with an emphasis on helping the reader make informed decisions, particularly when treating patients for which several treatment approaches may be appropriate because trial data does not clearly define the best option. Emerging therapeutic areas are evaluated, as work continues to identify agents that produce superior morphologic responses and visual acuity gains by targeting other molecules that contribute to diabetic retinopathy. Promising new drugs, targets and delivery systems are identified, and their development analysed.

Contains information from the Diabetic Retinopathy Clinical Research network not to be found in other published works Evidence-based approach includes material labeled with level of supporting evidence and many clinical examples Includes discussions of area of controversy

Diabetic retinopathy (DR), a common microvascular complication, has consistently been shown to be associated with an increased risk of cardiovascular disease (CVD). This book provides complete coverage of DR as a potential marker for CVD in those with diabetes. It succinctly reviews the epidemiological and pathogenic links of DR to various cardiovascular events including stroke, coronary artery disease, chronic kidney disease, heart failure, and mortality. Furthermore, it discusses the usefulness of DR in CVD risk prediction and cardiovascular safety of anti-VEGF therapy in diabetic patients. There are insights from contemporary diabetic trials that demonstrated the enhanced cardiovascular benefit of novel glucose lowering therapy. It also highlights the potential of novel retinal imaging to predict CVD and its risk factors using the state-of-the art artificial intelligence-based deep learning systems. This book will be an invaluable resource for specialists translating research findings into clinical care, including those in cardiology, endocrinology, ophthalmology, and general practitioners. IT will also be of interest to public health practitioners, researchers, graduate students, and biotech companies interested in developing retinal image-based diagnostic and prognostic tools.

The incidence of diabetes is increasing worldwide at an alarming rate, and diabetic retinopathy is one of the most significant complications of diabetes. Packed with outstanding retinal photos, the second edition of this one-stop clinical manual offers a comprehensive overview of the diagnosis, treatment and long–term management of patients with diabetic eye disease. Edited and authored by world-renowned experts from leading centres of excellence, A Practical Manual of Diabetic Retinopathy Management presents evidence-based guidance relevant for a global audience of health-care professionals, including diabetologists, ophthalmologists, retinal screeners, optometrists, ophthalmic nurses, GPs, and medical students.

Approximately 2.4 million Canadians suffer from diabetes and are likely to develop diabetic retinopathy. This disease of the retina caused by diabetes affects 99 percent of people with type 1 diabetes and 60 percent of those with type 2 diabetes in the first 20 years after the onset of diabetes. Early detection has thus become a major issue in the fight against diabetic retinopathy, especially since very effective treatments are available that can not only slow progression of the disease but also even restore lost vision. Written in simple and clear language, by doctors specializing in eye disorders, this book covers all aspects of the disease and provides important information for those who have diabetic retinopathy and people close to them.

Diabetic Retinopathy: The Essentials is written for general ophthalmologists and optometrists as well as family practitioners, diabetologists, and internists who encounter diabetic patients on a daily basis. It focuses on the diagnosis and management of diabetic retinopathy from the point of view of the retinal specialist. The book begins with the epidemiology, anatomy, and pathophysiology of diabetic retinopathy, and then covers important topics such as classification issues, diagnostic testing, examination techniques, new treatment modalities, patient management, indications for vitrectomy, pregnancy concerns, and informed consent. Coverage includes both general medical issues in diabetes and specifically ophthalmologic concerns. Features include more than 200 full-color photographs, case studies, and algorithms for patient management. A companion website includes the full text online and an image bank.

This book addresses diabetic retinopathy, an eye disease that remains one of the main causes of vision loss if not diagnosed and managed properly. It aims to cover the entire spectrum of the disease by describing its clinical identification and characterization, pathophysiology, epidemiology, and medical and surgical management. Diabetic Retinopathy also offers a complete overview of the present understanding of diabetic retinopathy, covering current practice but also including original contributions that offer novel perspectives for looking at and addressing this disease. The author has dedicated his lifetime to the study of diabetic retinal disease and has organized this book around his personal experience but at the same time giving the necessary information for updated management of diabetic retinopathy. Diabetic Retinopathy will be especially useful for postgraduate students in diabetology, retina specialists and researchers.

The aim of this book is to provide a comprehensive overview of current concepts in pathogenesis, diagnosis and treatments of diabetic retinopathy. It provides a collection of topics written by excellent authors, covering discussions on advances in understanding of pathophysiology, immunological factors and emerging concepts, relating to clinical aspects and treatment strategies. The contents of the book will not only provide a resource for our knowledge but also improve diagnosis and treatment options for those patients who suffer vision loss due to diabetic retinopathy.