Diagnosing Giants

Mackowiak traces the history of medicine through the illnesses of some of the most influential figures of the past. The diseases suffered by these figures had profound effects on their lives and their legacies.

A top behavioral geneticist makes the case that DNA inherited from our parents at the moment of conception can predict our psychological strengths and weaknesses. In Blueprint, behavioral geneticist Robert Plomin describes how the DNA revolution has made DNA personal by giving us the power to predict our psychological strengths and weaknesses from birth. A century of genetic research shows that DNA differences inherited from our parents are the consistent lifelong sources of our psychological individuality—the blueprint that makes us who we are. Plomin reports that genetics explains more about the psychological differences among people than all other factors combined. Nature, not nurture, is what makes us who we are. Plomin explores the implications of these findings, drawing some provocative conclusions—among them that parenting styles don't really affect children's outcomes once genetics is taken into effect. This book offers readers a unique insider's view of the exciting synergies that came from combining genetics and psychology. The paperback edition has a new afterword by the author.

This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Covering all aspects of cardiovascular pathology, including new cardiac devices, molecular panels and genetics, the latest tumor classifications, up-to-date COVID-19 information, and imaging, this volume incorporates the most recent scientific and technical knowledge in the field to provide a comprehensive overview of all key issues relevant to today’s practice. Richly illustrated and easy to use, the third edition of Diagnostic Pathology: Cardiovascular is a visually stunning, one-stop resource for every practicing pathologist, resident, student, or fellow as an ideal day-to-day reference or as a reliable training resource. Covers all areas of cardiovascular pathology, organizing chapters by how specimens are most often encountered in practice—biopsy, explant and surgical specimens, and autopsy—as well as by anatomic site Contains significantly updated information throughout (text, images, illustrations, and references) including the latest World Health Organization and International Collaboration on Cancer Reporting tumor classifications, as well as new details related to staging and grading of tumors of the heart, and COVID-19 information Evaluates a new generation of cardiac devices in surgical and autopsy specimens in both images and text Includes new material on genetics and sudden cardiac death and cardiomyopathy, and recent recommended amyloid treatment therapies Features nearly 1,500 images, including carefully annotated histology and gross pathology photographs, vivid medical illustrations, photomicrographs, and electron micrographs to help practicing and in-training pathologists reach a confident diagnosis Employs consistently templated chapters, bulleted content, key facts, a variety of tables, annotated images, pertinent references, and an extensive index for quick, expert reference at the point of care

This book systematically describes the achievements and current situation of in vitro diagnostic (IVD) industry in China. It consists of twelve parts, including the overview on the IVD industry in China in 2021, hot technologies and products of IVD industry, academic, technological and product development in the field of IVD, such as biochemical diagnosis, immune-diagnosis, point-of-care testing, molecular diagnosis, blood and body fluid diagnosis, microbial detection, laboratory assembly line, etc. In this second edition, the new contents added include the development of new coronavirus molecular diagnostic products, flight mass spectrometry, tandem mass spectrometry, tumor markers, ELISA immune reagents, autoimmune diagnostics, concomitant diagnosis, fecal and intestinal microecology detection, pathological diagnosis, raw materials for in vitro diagnostic reagents, standard substances and quality controls for in vitro diagnostic reagents, etc., making the content of the whole book more novel and rich. This book is compiled by an editorial committee composed of well-known entrepreneurs, experts and professors in IVD industry in China. It is a reference book for practitioners of IVD industry, medical laboratory and medical staffs all over the world.

One of Washington Independent Review of Books' 50 Favorite Books of 2018 • A Buzzfeed Best Book of 2018 "Morbidly witty." —Marilyn Stasio, The New York Times "You’ll be as appalled at times as you are entertained." —Bustle, one of The 17 Best Nonfiction Books Coming Out In June 2018 "A heady mix of erudite history and delicious gossip." —Aja Raden, author of Stoned In the Washington Post roundup, "What your favorite authors are reading this summer," A.J. Finn says, “I want to read The Royal Art of Poison, Eleanor Herman’s history of poisons." Hugely entertaining, a work of pop history that traces the use of poison as a political—and cosmetic—tool in the royal courts of Western Europe from the Middle Ages to the Kremlin today The story of poison is the story of power. For centuries, royal families have feared the gut-roiling, vomit-inducing agony of a little something added to their food or wine by an enemy. To avoid poison, they depended on tasters, unicorn horns, and antidotes tested on condemned prisoners. Servants licked the royal family’s spoons, tried on their underpants and tested their chamber pots. Ironically, royals terrified of poison were unknowingly poisoning themselves daily with their cosmetics, medications, and filthy living conditions. Women wore makeup made with mercury and lead. Men rubbed turds on their bald spots. Physicians prescribed mercury enemas, arsenic skin cream, drinks of lead filings, and potions of human fat and skull, fresh from the executioner. The most gorgeous palaces were little better than filthy latrines. Gazing at gorgeous portraits of centuries past, we don’t see what lies beneath the royal robes and the stench of unwashed bodies; the lice feasting on private parts; and worms nesting in the intestines. In The Royal Art of Poison, Eleanor Herman combines her unique access to royal archives with cutting-edge forensic discoveries to tell the true story of Europe’s glittering palaces: one of medical bafflement, poisonous cosmetics, ever-present excrement, festering natural illness, and, sometimes, murder.

Through five well-regarded editions, Dr. David Dabbs’ Diagnostic Immunohistochemistry has set the standard for concise, complete, guidance on the use and interpretation of immunohistochemical stains. The 6th Edition continues this tradition of excellence, bringing you fully up to date with all aspects of this dynamic field. Easy to use and understand, this practical resource distills the large body of information on immunohistochemistry into a single, convenient reference that is invaluable for today’s surgical pathologists. Covers all aspects of the field, with an emphasis on the role of genomics in diagnosis and theranostic applications that will better inform treatment options. Includes the latest grading schemes in several organs along with new antibodies to cover more genomic immunohistochemistry applications. Contains current biomarker guidelines and up-to-date references throughout. Offers a systematic approach to the diagnostic entities of each organ system, including detailed differential diagnoses, diagnostic algorithms, and immunohistograms that depict immunostaining patterns of tumors. Contains numerous charts and tables, as well as 1,500 high-quality color histologic images that assist in making a definitive diagnosis. Discusses diagnostic pitfalls through immunohistologic differential diagnosis wherever appropriate so you can provide the most accurate diagnoses. Covers many more antigens than other texts, and discusses antibody specifications with tables that convey information on uses, clones, vendors, sources, antibody titers, and types of antigen retrieval.

Patients as Art explores the capacity of art to provide a unique perspective on the history of humankind. Fearturing over 160 full-color works of art, this book offers a pictorial review of medical history stretching from Paleolithic times to the present, reflecting the ideals and sensibilities of the times in which they were created, and communicating formal, spiritual, and scientific values. Rarely have experts considered the potential clinical implications of such works or their collective value as an archive of medical history. Many prominent works of art have depicted aspects of medicine's long struggle against ignorance, superstition, and religious and political dogma to emerge as one of mankind's greatest achievements. The particular works included in this book were chosen both for their esthetic appeal and for the skill with which they depict important developments in medicine over time. Dr. Mackowiak reveals what these works have to say about the status of the "art of medicine" in the past, and its relationship to the medicine of today.

The OUPblog Tenth Anniversary Book: Ten Years of Academic Insights for the Thinking World celebrates the incisive works that made the OUPblog what it is today: an unrivaled source for sophisticated learning, understanding, and reflection. Hand-picked by Oxford University Press editors, these selections feature James M. McPherson on Lincoln's greatest moment, Arne L. Kalleberg's on police brutality in Ferguson, Missouri, and Anatoly Liberman's exploration into the origins of the word "bigot, ̈among many others. From the fall of Rome and the science of happiness, to race relations and international law, the OUPblog has adapted the insights of authors, staff, and friends of Oxford University Press for an entire decade, earning its place as a 2013 Webby Award Honoree. Since 2005, more than 8,000 articles have been published, featuring daily commentary on a wide range of topics spanning politics, science, philosophy, music, and everything in between. Today, the OUPblog continues to represent the Oxford University Press's commitment to excellence in research, scholarship, and education, disseminating insights from the world's greatest thinkers.