Drugs Of Choice 2021

“Hart’s argument that we need to drastically revise our current view of illegal drugs is both powerful and timely . . . when it comes to the legacy of this country’s war on drugs, we should all share his outrage.” —The New York Times Book Review From one of the world's foremost experts on the subject, a powerful argument that the greatest damage from drugs flows from their being illegal, and a hopeful reckoning with the possibility of their use as part of a responsible and happy life Dr. Carl L. Hart, Ziff Professor at Columbia University and former chair of the Department of Psychology, is one of the world's preeminent experts on the effects of so-called recreational drugs on the human mind and body. Dr. Hart is open about the fact that he uses drugs himself, in a happy balance with the rest of his full and productive life as a researcher and professor, husband, father, and friend. In Drug Use for Grown-Ups, he draws on decades of research and his own personal experience to argue definitively that the criminalization and demonization of drug use--not drugs themselves--have been a tremendous scourge on America, not least in reinforcing this country's enduring structural racism. Dr. Hart did not always have this view. He came of age in one of Miami's most troubled neighborhoods at a time when many ills were being laid at the door of crack cocaine. His initial work as a researcher was aimed at proving that drug use caused bad outcomes. But one problem kept cropping up: the evidence from his research did not support his hypothesis. From inside the massively well-funded research arm of the American war on drugs, he saw how the facts did not support the ideology. The truth was dismissed and distorted in order to keep fear and outrage stoked, the funds rolling in, and Black and brown bodies behind bars. Drug Use for Grown-Ups will be controversial, to be sure: the propaganda war, Dr. Hart argues, has been tremendously effective. Imagine if the only subject of any discussion about driving automobiles was fatal car crashes. Drug Use for Grown-Ups offers a radically different vision: when used responsibly, drugs can enrich and enhance our lives. We have a long way to go, but the vital conversation this book will generate is an extraordinarily important step.

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This book examines the U.S. war on drugs at home and abroad. It provides a brief history of the war on drugs. In addition, it analyzes drug trafficking and organized crime in Colombia and Mexico, and the role of the United States government in counternarcotics policies. This work also examines the opioid epidemic, addiction, and alternative policies.

This report presents the recommendations of the WHO Expert Committee responsible for updating the WHO Model List of Essential Medicines. The first part contains a progress report on the new procedures for updating the Model List and the development of the WHO Essential Medicines Library. It continues with a section on changes made in revising the Model List followed by a review of some sections such as hypertensive medicines and fast track procedures for deleting items. Annexes include the 13th version of the Model List and items on the list sorted according to their 5-level Anatomical Therapeutic Chemical classification codes.

This book provides a broad overview of rare disease drug development. It offers unique insights from various perspectives, including third-party capital providers, caregivers, patient advocacy groups, drug development professionals, marketing and commercial experts, and patients. A unique reference, the book begins with narratives on the many challenges faced by rare disease patient and their caregivers. Subsequent chapters underscore the critical, multidimensional role of patient advocacy groups and the novel approaches to related clinical trials, investment decisions, and the optimization of rare disease registries. The book addresses various rare disease drug development processes by disciplines such as oncology, hematology, pediatrics, and gene therapy. Chapters then address the operational aspects of drug development, including approval processes, development accelerations, and market access strategies. The book concludes with reflections on the authors' case for real-world data and evidence generation in orphan medicinal drug development. Rare Disease Drug Development is an expertly written text optimized for biopharmaceutical R&D experts, commercial experts, third-party capital providers, patient advocacy groups, patients, and caregivers.

Journalist and author of the New York Times bestselling Unbroken Brain tackles the revolutionary concept of harm reduction, how it can transform the treatment of addiction, and how it holds the potential to revolutionize our treatment of behavioral and societal issues. In her New York Times bestseller Unbroken Brain, journalist Maia Szalavitz took an unflinching look at addiction, challenging the idea of the "broken brain" to offer a groundbreaking perspective on addiction as a learning disorder. Now she turns her keen eye and narrative powers to the surprisingly simple--and extremely divisive--practice of harm reduction, which is a revolutionary means to solving the drug addiction crisis. Drug overdoses now kill more Americans annually than guns, cars or breast cancer. But in the name of "sending the right message," we have criminalized drug addiction, denied those who are addicted medical care, housing and other benefits, and have deliberately allowed the spread of fatal diseases. Yet there is an alternative to our present system, one that has been proven to work, but which runs counter to the received wisdom of our criminal and medical industrial complexes. It is called harm reduction. A surprisingly simple idea with enormous power, harm reduction takes the focus off of drug use and instead works to minimize associated damage. It represents the philosophy behind needle exchange programs and providing heroin addicts with the overdose medication naloxone instead of arresting them. It is focused not on punishing pleasure but on minimizing harm; in essence, it is a wholesale refutation of the American way of justice. Undoing Drugs tells the story of harm reduction. It will show how this concept has begun to transform the treatment of addiction and how it holds the potential to revolutionize how we deal with a range of other urgent behavioral and societal issues. Harm reduction challenges people to prioritize radical empathy and kindness over punishment as a way of not only dealing with drug use, but also in questions related to racism, sexism, disability and inequality. And, as Szalavitz shows, it says unequivocally that we must be more concerned about saving lives and health than about criminalizing quality-of-life crimes. Szalavitz argues for a practical application of the Hippocratic oath to "First, do no harm" beyond medicine and to those who urgently need it most.