Electrochemical Biosensors

Electrochemical Biosensors summarizes fundamentals and trends in electrochemical biosensing. It introduces readers to the principles of transducing biological information to measurable electrical signals to identify and quantify organic and inorganic substances in samples. The complexity of devices related to biological matrices makes this challenging, but this measurement and analysis are critically valuable in biotechnology and medicine. Electrochemical biosensors combine the sensitivity of electroanalytical methods with the inherent bioselectivity of the biological component. Some of these sensor devices have reached the commercial stage and are routinely used in clinical, environmental, industrial and agricultural applications. - Describes several electrochemical methods used as detection techniques with biosensors - Discusses different modifiers, including nanomaterials, for preparing suitable pathways for immobilizing biomaterials at the sensor - Explains various types of signal monitoring, along with several recognition systems, including antibodies/antigens, DNA-based biosensors, aptamers (protein-based), and more

This book broadly reviews the modem techniques and significant applications of chemical sensors and biosensors. Chapters are written by experts in the field – including Professor Joseph Wang, the most cited scientist in the world and renowned expert on sensor science who is also co-editor. Each chapter provides technical details beyond the level found in typical journal articles, and explores the application of chemical sensors and biosensors to a significant problem in biomedical science, also providing a prospectus for the future.This book compiles the expert knowledge of many specialists in the construction and use of chemical sensors and biosensors including nitric oxide sensors, glucose sensors, DNA sensors, hydrogen sulfide sensors, oxygen sensors, superoxide sensors, immuno sensors, lab on chip, implatable microsensors, et al. Emphasis is laid on practical problems, ranging from chemical application to biomedical monitoring and from in vitro to in vivo, from single cell to animal to human measurement. This provides the unique opportunity of exchanging and combining the expertise of otherwise apparently unrelated disciplines of chemistry, biological engineering, and electronic engineering, medical, physiological. - Provides user-oriented guidelines for the proper choice and application of new chemical sensors and biosensors - Details new methodological advancements related to and correlated with the measurement of interested species in biomedical samples - Contains many case studies to illustrate the range of application and importance of the chemical sensors and biosensors

Since four decades, rapid detection and monitoring in clinical and food diagnostics and in environmental and biodefense have paved the way for the elaboration of electrochemical biosensors. Thanks to their adaptability, ease of use in relatively complex samples, and their portability, electrochemical biosensors now are one of the mainstays of analy

This book focuses on the basic electrochemical applications of DNA in various areas, from basic principles to the most recent discoveries. The book comprises theoretical and experimental analysis of various properties of nucleic acids, research methods, and some promising applications. The topics discussed in the book include electrochemical detection of DNA hybridization based on latex/gold nanoparticle and nanotubes; nanomaterial-based electrochemical DNA detection; electrochemical detection of microorganism-based DNA biosensors; gold nanoparticle-based electrochemical DNA biosensors; electrochemical detection of the aptamer-target interaction; nanoparticle-induced catalysis for DNA biosensing; basic terms regarding electrochemical DNA (nucleic acids) biosensors; screen-printed electrodes for electrochemical DNA detection; application of field-effect transistors to label free electrical DNA biosensor arrays; and electrochemical detection of nucleic acids using branched DNA amplifiers.

Electrochemical Nano-biosensors: Applications in Diagnostics, Therapeutics, Environment, and Food Management features a critical overview of different, recently reported nanomaterial-based electrochemical sensing and biosensing strategies. It is based on various analytical approaches for the point-of-care or POC healthcare related diagnostics, evaluation of contaminants, additives and adulterants in foods and environment management. Each section under the topic is discussed in its exhaustive detail, incorporating significant literature reviews spanning over two decades. The book critically analyzes issues and challenges for its applications in real world settings, universal applicability in resource limited sets-ups of remote areas, ease of integration with other sensing platforms, portability/miniaturization, and more. - Takes account of the fact that nanomaterials are increasingly favored as labels for electrochemical immunoassay protocols for the development of highly sensitive and selective electrochemical sensing device - Refines biosensors for real-world settings, academicians, healthcare professionals and industrialist who need to team up for the successful realization of POCT/LOCT devices - Contains focused and targeted research coupled with other technological advances to help in the development of cutting-edge nanomaterial based electrochemical immunoassays with features of test-strip technology and lateral flow

This book illustrates recent advances in developing sensitive and selective electrochemical biosensors for their whole blood application. Known to be a cutting-edge and fast-growing technology, electrochemical biosensors demonstrate their potential in laboratories, industries, and healthcare to achieve specific and direct target detection in complex media, and have become an emerging technology for guiding personalized medicine. The book first demonstrates methods and models to cover the detection of a variety of target molecules in whole blood, including ions, small molecules, nucleic acids, proteins, cells, etc. Then, it provides comments on various detection strategies employed to improve sensors' sensitivity, specificity, selectivity, and reproducibility as well as presenting the laws and principles. In addition, it summarizes achievements and challenges from recent years. Finally, it provides future perspectives and opportunities in electrochemical biosensors including point of care detection, molecular diagnostics and the integration of this sensor platform with multidisciplinary technologies, towards the ultimate goal of personalized medicine. The book integrates abundant viewpoints from multiple sciences and is helpful and valuable to a wide readership in the various fields of biochemistry, biophysics, bioengineering, and pharmaceutics.

A biosensor is an integrated receptor-transducer device that converts a biological response into an electrical signal. The design and development of biosensors have taken center stage for researchers or scientists in the recent decade owing to the wide range of biosensor applications in healthcare and disease diagnosis, environmental monitoring, water and food quality, and drug delivery. Due to their adaptability, ease of use in relatively complex samples, and portability, the significance of electrochemical biosensors in analytical chemistry has increased manifold. Electrochemistry has been pivotal in developing transduction methods for biological processes and biosensors. In parallel, the explosion of activity in nanoscience and nanotechnology and their huge success have profoundly affected biosensor technology, opening new avenues of research for electrode materials and transduction. Electrochemical Biosensors in Practice: Material and Methods particularly explores the use of silver and gold nanoparticles for signal amplification, photocurrent transduction, and aptamer design. Therefore, the book serves as an introductory text for those specializing in biosensors and bioelectronics and their practical applications. Key features Includes structured information for easy understanding of the subject Provides an introduction to biosensors and electrochemical biosensor classification Explains fundamental concepts and practical electrochemistry techniques for research Provides notes on essential electrochemical sensor materials such as graphene, carbon nanotubes, conductive polymers, and other advanced materials Provides information about electrochemical biosensor development Informs readers about recent applications and research findings Includes references for further reading

This book is an extensive review of Electrochemical Biosensor for Food Safety. This book will provide information on history, classification, and application of electrochemical biosensor for food safety.