Elements Of Molecular Neurobiology

This edition of the popular text incorporates recent advances in neurobiology enabled by modern molecular biology techniques. Understanding how the brain works from a molecular level allows research to better understand behaviours, cognition, and neuropathologies. Since the appearance six years ago of the second edition, much more has been learned about the molecular biology of development and its relations with early evolution. This "evodevo" (as it has come to be known) framework also has a great deal of bearing on our understanding of neuropathologies as dysfunction of early onset genes can cause neurodegeneration in later life. Advances in our understanding of the genomes and proteomes of a number of organisms also greatly influence our understanding of neurobiology. * Well known and widely used as a text throughout the UK, good reviews from students and lecturers. * Good complement to Fundementals of Psychopharmacology by Brian Leonard. This book will be of particular interest to biomedical undergraduates undertaking a neuroscience unit, neuroscience postgraduates, physiologists, pharmacologists. It is also a useful basic reference for university libraries. Maurice Elphick, Queen Mary, University of London "I do like this book and it is the recommended textbook for my course in Molecular Neuroscience. The major strength of the book is the overall simplicity of the format both in terms of layout and diagrams."

Few human enterprises have the impact and the influence that neuroscience has. We can now examine our highest functions and malfunctions, including the processes of learning, aging, and behavior. The knowledge gained gives mankind previously unimaginable power for improvement, but also great responsibility that the knowledge be used for beneficial, not harmful, purposes. The Handbook of Neurochemistry and Molecular Neurobiology focuses on available knowledge in neurochemistry and molecular biology of the nervous system. Successful research requires interdisciplinary teamwork, where the lines between neurochemistry and related areas are obscure and need to be crossed. This is reflected in the selection of the various volumes we know others could have been added, and it is likely that each volume could have been expanded to a set of volumes and that a detailed coverage of the field would require over 100 volumes. This may not have been practical or preferable, and it may be better to have a shorter overview of essential information, with guiding of the reader, if necessary, seeking more details in our ever-expanding and developing area of research. This edition, unlike the previous ones, will not be a static, but more a living set of chapters that will be updated. If needed, new chapters added on the website, even after the appearance of the printed version. The Handbook is intended to be a service to the neuroscience community, to help in finding available and useful information, to point out gaps in our knowledge, and to encourage continued studies. It represents the valuable contributions of the many authors of the chapters and the guidance of the editors and mostimportant, it represents support for research in this discipline. Based on the rapid advances in the years since the second edition, we can be very optimistic and hopeful that successful therapy for pathology, neural and behavioral (since they are interconnected), and perhaps even an expansion of learning, will be achieved, and described in the next edition.

Extensively updated, revised and illustrated this unique introductory text presents a molecular account of the structure, function and development of the brain and nervous systems. This book describes the latest research in neurobiology made possible by modern molecular biology techniques. The author synthesizes this new knowledge and demonstrates how an understanding at the molecular level can contribute towards a theory of the brain in health and disease.

This new addition to the Frontiers in Molecular Biology series, written by internationally known experts, provides a detailed account of the current knowledge in this rapidly changing field. A useful alternative to multiple sources, this text provides in-depth coverage of such topics as the molecular biology of receptors and ion channels, as well as the use of Drosophila as a neurological model. More than just a collection of articles, this carefully edited volume gives the reader a wealth of up-to-date information in a lively, cohesive format.

"The Handbook is intended to be a service to the neuroscience community, to help in finding available and useful information, to point out gaps in our knowledge, and to encourage continued studies. It represents the valuable contributions of the many authors of the chapters and the guidance of the editors and most important, it represents support for research in this discipline. Based on the rapid advances in the years since the second edition."--Publisher's website.

Molecular Approaches to Neurobiology deals with molecular approaches to the analysis of the nervous system. This book surveys the current state of knowledge in a number of areas of molecular neurobiology that includes the subcellular level of chromatin structure, complexity of RNA synthesis, role of hormones in cell differentiation, and molecular correlates between neuropeptides and behavior. A comprehensive review of procedures for the isolation of specific brain cells and their experimental use is also provided at the end of this text. This publication is useful to those working in the field of neurochemistry and those engaged in morphological and physiological approaches to the analysis of the nervous system, as well as molecular biologists and biochemists working with non-neural tissues.

This textbook provides an introduction to neuroscience, focusing particularly on the rapidly developing molecular aspects. The techniques of molecular biology are introduced and described in the context of their role in elucidating brain function at the molecular level.