Emerging Materials And Technologies For Bone Repair And Regeneration

This book covers advancements in the field of bone repair and regeneration. It introduces bone development, repair, and regeneration and details different biomaterials and technologies involved in the fabrication and characterization of bone-related scaffolds and implants. The book explores nanotechnological intervention and folklore phytomedicines and their prospects in regenerating bone including major bone related disease conditions, infection, and their tackling via tissue engineering strategies. FEATURES: Covers polymer materials and technologies for bone repair and regeneration based on tissue engineering Defines the interdisciplinary mechanism of bone tissue repair ranging from the fields of material science, nanotechnology, and phytomedicine includes basic sciences, scaffolds, and bone infection Examines fabrication and characterization methods for the bone repair materials Reviews fundamentals of interlinked mechanisms of bone development, repair, and regeneration. This book is aimed at graduate students and researchers in biomedical and tissue engineering and biomaterial sciences.

"This book emphasizes on advancement in the field of bone repair and regeneration. It introduces bone development, repair and regeneration emphasizing the correlation of the processes including details about different biomaterials and technologies involved in the fabrication, characterization of bone related scaffolds and implants. The realm of nanotechnological intervention and folklore phytomedicines and their prospects in regenerating bone is explored including major bone related disease conditions, infection, and their tackling via tissue engineering strategies. Covers polymer materials and technologies for bone repair and regeneration based on tissue engineering Defines the interdisciplinary mechanism of bone tissue repair ranging from the fields of material science, nanotechnology, and phytomedicine Includes basic sciences, scaffold-based approach, and bone infection Examines fabrication and characterization methods required for finalizing the bone repair materials Reviews fundamentals of interlinked mechanisms of bone development, repair, and regeneration This book is aimed at graduate students and researchers in biomedical and tissue engineering, and biomaterial sciences"--

Bone Repair Biomaterials: Regeneration and Clinical Applications, Second Edition, provides comprehensive reviews on materials science, engineering principles and recent advances. Sections review the fundamentals of bone repair and regeneration, discuss the science and properties of biomaterials used for bone repair, including metals, ceramics, polymers and composites, and discuss clinical applications and considerations, with chapters on such topics as orthopedic surgery, tissue engineering, implant retrieval, and ethics of bone repair biomaterials. This second edition includes more chapters on relevant biomaterials and a greatly expanded section on clinical applications, including bone repair applications in dental surgery, spinal surgery, and maxilo-facial and skull surgery. In addition, the book features coverage of long-term performance and failure of orthopedic devices. It will be an invaluable resource for researchers, scientists and clinicians concerned with the repair and restoration of bone. Provides a comprehensive review of the materials science, engineering principles and recent advances in this important area Presents new chapters on Surface coating of titanium, using bone repair materials in dental, spinal and maxilo-facial and skull surgery, and advanced manufacturing/3D printing Reviews the fundamentals of bone repair and regeneration, addressing social, economic and clinical challenges Examines the properties of biomaterials used for bone repair, with specific chapters assessing metals, ceramics, polymers and composites

Biomaterials Effect on the Bone Microenvironment Practical resource on clinical bone regeneration from a variety of related interdisciplinary researchers Biomaterials Effect on the Bone Microenvironment focuses on the structure-activity relationship between bone biomaterials and microenvironment regulation, presenting a systematic exposition from all aspects of biomaterials regulated microenvironment in bone regeneration and covering design strategies, applications, and mechanisms of biomaterials that regulate bone microenvironment, along with the methods for manufacturing biomaterials and their clinical translation. The subject’s potential challenges and future development direction are discussed, and the design and initiative principle of tailored biomaterials with various features, including bioactive components and physicochemical property, are elucidated in depth. Numerous biomaterials, including natural and synthetic, are summarized and compared. Their advantages and features are also evaluated, particularly in bone microenvironmental regulation and bone generation. Moreover, the stimulation mechanism of the microenvironment to bone generation is discussed in detail, including mechanical-support effect, redox effect, pro-angiogenesis effect, inflammatory immune effect, and anti-aging effect. Biomaterials Effect on the Bone Microenvironment provides further coverage of sample topics such as: Role of bone microenvironment and its associated biomaterials in modulation bone diseases, reviewing the biomaterials used to regulate bone microenvironment Relationship between biological factors of various materials and physiological functions in bone microenvironment Application of the third generation of biomaterials, which would regenerate the bone to regulate bone microenvironment Emerging biological material manufacturing technology and mechanisms of novel biomaterial modulating microenvironment for bone regeneration Future outlook of bone tissue engineering along with the general process of bone remodeling and regeneration With comprehensive coverage of one of the most promising and valuable candidates for clinical bone regeneration, Biomaterials Effect on the Bone Microenvironment is an ideal resource for materials scientists, biotechnologists, biochemists, bioengineers, orthopedists, and clinical chemists who want to stay on the cutting edge of this rapidly evolving field.

This volume summarizes recent developments in the use of new materials and technologies in healthcare. The emphasis is on new approaches that incorporate bioactive materials and scaffolds with cells in the emerging technologies of tissue engineering and regenerative medicine. The incorporation of nanotechnology, stem cells, and gene control of cells is included in the current research discussed. Clinical applications are described throughout the volume, along with economic and bioethics issues. The chapters are organized into four sections of clinical needs and an overview that summarizes the technologies that provide new approaches to clinical problems. The clinical areas addressed are Skeletal and Skin Repair, Heart and Cardiovascular Repair, Neuronal Repair, and Sensory Repair. The chapters were written by a multidisciplinary group of authors from six universities: the University of Arizona (US), the University of Central Florida (US), Imperial College London (UK), King''s College, Guy''s Hospital, University of London (UK), University of Florida (US) and Kyoto University (Japan). This book can be used as a reference book or as a textbook for advanced undergraduate or graduate courses in bioengineering, biomaterials or healthcare management.

A fundamental aspect of the rapidly expanding medical care sector, bone repair continues to benefit from emerging technological developments. This text provides researchers and students with a comprehensive review of the materials science and engineering principles behind these developments. The first part reviews the fundamentals of bone repair and regeneration. Further chapters discuss the science and properties of biomaterials used in bone repair, including both metals and biocomposites. Final chapters analyze device considerations such as implant lifetime and failure, and discuss potential applications, as well as the ethical issues that continually confront researchers and clinicians.

Calcium-based natural minerals are important for a wide range of applications. Though these materials are available in nature, researchers are working toward developing them in the laboratory. Calcium-Based Materials: Processing, Characterization, and Applications introduces the possibility of designing these materials for particular applications. Introduces a variety of calcium-based materials and discusses synthesis, growth, and stability Provides in-depth coverage of calcium carbonate Discusses applications of calcium-based minerals in different fields Includes details on synchrotron X-ray tools for case minerals This comprehensive text is aimed at researchers in materials science, engineering, and bioengineering.

Mechanics of Auxetic Materials and Structures offers a wide range of application-based and practical considerations of smart materials and auxetic materials in engineering structures. Exploring the analytical and numerical solution procedures, the book discusses crucial characteristics of metamaterials and their response to external factors. Covering the effect of different parameters and external factors on the mechanics of auxetic materials and structures, the book considers the benefits leading to better fracture resistance, toughness, shear modulus, and acoustic response. The book serves as a reference for senior undergraduate and graduate students studying civil engineering, mechanical engineering, and materials science and taking courses in smart materials, metamaterials, and mechanics of materials.