Endocrine Aspects Of Successful Aging Genes Hormones And Lifestyles

At the beginning of the 20th century, life expectancy at birth in North America and Western Europe was around 50 years of age. Nowadays, women have gained more than 30 years of age and men are trailing closer. However, according to several sociologists such as Louis Chauvel, the notion of a "greying society" is not entirely adequate since aging people are physically and socially younger and more active for a longer time. Of course, the other side of the medal is to tackle the challenge of preventing age-associated chronic diseases. In this book the extensive field of research on neuroendocrine aging has been reviewed. Aging is one of the most complex biological processes determined by the interactions between genetic and environmental factors.

This second edition of Health Aspects of Aging serves to broaden the perspectives of societal change due to increases in life expectancy, as well as the effects of age-related changes as they impinge upon the provision of health care for older persons. The growing presence of a large number of persons aged 65 and older worldwide has propelled a re-evaluation of the nature of life that is protracted to 100 years and beyond. The emphasis in this second edition is to replace the prevailing problem approach to aging by a problem-solving approach. The problem-solving approach of this volume has allowed for the incorporation of the concept of new social structures and the development of intervention and prevention strategies along with new technologies. Such new products and health care measures include those that are deliberately aimed to offset debilities due to normal age changes, the onslaught of diseases, incongruous environments, and altered social states. Such a multi-disciplinary perspective underscores the fact that aging permeates not only biological systems, but clinical medicine, economics, ethics, and the very fabric of society. The chapters in this volume address these issues from the standpoints of diverse disciplines and professional positions. Since biological changes are primary issues, the aging process is largely described from the perspective of biological changes related to age and to particular dysfunctions. The environmental features and the potential introduction of technological interventions are interspersed within chapters, as well as finding primary focus in particular chapters. The maturity of the technology described in the chapters varies, from devices and systems that are nearly ready to be marketed to concepts and prototypes that are still in the design and developmental stages in the laboratory. The relationship between the provision of appropriate health care and the responsible utilization of technologies as described in this volume will serve to enhance the nature of life extension.

Extensively revised and updated to reflect the current state of knowledge in the study of aging, this Fourth Edition offers a complete profile of the aging process at all levels, from molecules and cells to demography and evolution. Written by international experts in current basic and clinical aging research, this text includes aspects of individual, comparative, and differential aging, and discussions of theories and mechanisms of aging. This invaluable reference illustrates how bodily systems, organs, and functions are affected with aging, describes how genetic and environmental factors influence age-related changes, and addresses some of the clinical consequences of these changes for health and longevity. Well illustrated, with numerous tables and graphs, this book presents up-to-date information from internationally renowned experts in various bio-medical fields.

One of the problems geriatricians are confronted with in everyday clinical practice is differentiating disease from the process of old age. The challenges of ageing require a better understanding of the essential biology of ageing in order to separate ageing from disease, and indeed ageing made worse by disease. Although the topic is large and diverse, this practical and easy-to-read reference book contains vital information on the biology of ageing. It provides a concise understanding of the changes that occur and focuses on the clinical implications of ageing. MCQs are featured throughout for revision and examination practice. The Biology of Ageing provides the reader with: . a learning guide on the biology of ageing through an overview of the changes that occur at both cellular and system levels . knowledge of how biological changes of ageing impact on physiology and the clinical relevance in medical practice . a practical consideration of these changes in disease presentations and how these changes may impact on disease management. This full-colour guide featuring slides, MRIs, figures and photographs is ideal for doctors training in geriatric medicine, practising geriatricians and those with an interest in management of older people.

This book covers topics that range from fundamental studies of DNA replication, chromosomal and nuclear function through growth factor control of endocrine tumor initiation and progression. The basic and translational insights gained from Hormonal Control of Cell Cycle will be of interest to those studying the biology of endocrine tumors as well as those deriving novel therapeutic approaches for these benign and malignant disorders.

The interface of sexual behavior and evolutionary psychology is a rapidly growing domain, rich in psychological theories and data as well as controversies and applications. With nearly eighty chapters by leading researchers from around the world, and combining theoretical and empirical perspectives, The Cambridge Handbook of Evolutionary Perspectives on Sexual Psychology is the most comprehensive and up-to-date reference work in the field. Providing a broad yet in-depth overview of the various evolutionary principles that influence all types of sexual behaviors, the handbook takes an inclusive approach that draws on a number of disciplines and covers nonhuman and human psychology. It is an essential resource for both established researchers and students in psychology, biology, anthropology, medicine, and criminology, among other fields. Volume 3: Female Sexual Adaptations addresses theory and research focused on sexual adaptations in human females.

As aging trends in the United States and Europe in particular are strongly suggestive of increasingly older society, it would be prudent for health care providers to better prepare for such changes. By including physiology, disease, nutrition, pharmacology, pathology, radiology and other relevant associated topics, Geriatric Gastroenterology fills the void in the literature for a volume devoted specifically to gastrointestinal illness in the elderly. This unique volume includes provision of training for current and future generations of physicians to deal with the health problems of older adults. It will also serve as a comprehensive guide to practicing physicians for ease of reference. Relevant to the geriatric age group, the volume covers epidemiology, physiology of aging, gastrointestinal physiology, pharmacology, radiology, pathology, motility disorders, luminal disorders, hepato-biliary disease, systemic manifestations, neoplastic disorders, gastrointestinal bleeding, cancer and medication related interactions and adverse events, all extremely common in older adults; these are often hard to evaluate and judge, especially considering the complex aging physiology. All have become important components of modern medicine. Special emphasis is be given to nutrition and related disorders. Capsule endoscopy and its utility in the geriatric population is also covered. Presented in simple, easy to read style, the volume includes numerous tables, figures and key points enabling ease of understanding. Chapters on imaging and pathology are profusely illustrated. All chapters are written by specialists and include up to date scientific information. Geriatric Gastroenterology is of great utility to residents in internal medicine, fellows in gastroenterology and geriatric medicine as well as gastroenterologists, geriatricians and practicing physicians including primary care physicians caring for older adults.

This open access book takes a multidisciplinary approach to provide a holistic understanding of late old age, and situates the aged person within the context of family, caregivers, clinical and other institutions. All through the book, the author discusses preparedness for an aging individual as well as the society in the Indian context. The book highlights inevitable but mostly neglected health issues like depression, dementia, fall, and frailty and provides detailed analyses of solutions that are practicable in low resource settings. It also brings up intergenerational differences and harmony in the context of holistic care of older Indians. Alongside clinical perspectives, the book uses narratives of elderly patients to dwell on the myriad of problems and issues that constitute old age healthcare. Demonstrating cases that range from the most influential to the most underprivileged elderly in India, the book enlightens multiple caregivers—doctors, nurses, and professional caregivers as well as family members—about the dynamic approach required in dealing with complex issues related to late old age. The narratives make the book relatable and interesting to non-academic readers, with important lessons for gerontological and geriatric caregiving. It is also of use to older adults in preparing for active aging.