Endometrial Gene Expression
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Endometrial Gene Expression
Author | : Joanne Kwak-Kim |
Publsiher | : Springer Nature |
Total Pages | : 220 |
Release | : 2019-11-08 |
Genre | : Health & Fitness |
ISBN | : 9783030285845 |
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The endometrium goes through cyclical changes under the influence of hormones, and immune effectors in the endometrium change their populations cyclically as well. Dynamic changes in immune effectors determine endometrial cytokine and chemokine milieus and, consequently, the endometrial immune response. Endometrial immune responses have been shown to be important for trophoblast invasion and early pregnancy. Indeed, dysregulated endometrial inflammatory immune responses are associated with reproductive failures, such as recurrent pregnancy losses, repeated implantation failure, and gynecological diseases with oncogenic potential. Hence, the investigation of endometrial gene expression may predict infertility, gynecological and oncological conditions. This book presents the state of the art in endometrial gene expression as well as recent developmental findings relating to reproduction and reproductive disorders. It begins with a review of the genetic regulation of urogenital tract formation and molecular mechanism underlying the physiology of menstrual cycle before moving on to the current and emerging technological advances in molecular biology. Endometrial gene expressions of immune inflammatory conditions, viral infection, metabolic and nutritional conditions, and reproductive disorders are then presented in following chapters. Examples of the use and interpretation of gene expression in clinical scenarios including recurrent pregnancy losses, infertility and multiple implantation failures are presented with currently available endometrial gene analysis. Utilizing the latest evidence and clinical guidelines, Endometrial Gene Expression will be a cutting-edge resource for gynecologist, reproductive immunologist, reproductive endocrinologists, obstetrician, maternal fetal medicine specialist and other health care providers in the field of reproductive medicine.
Uterine Endometrial Function
Author | : Hideharu Kanzaki |
Publsiher | : Springer |
Total Pages | : 155 |
Release | : 2016-05-26 |
Genre | : Medical |
ISBN | : 9784431559726 |
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This book focuses on uterine endometrial function and receptivity from multiple perspectives. The chapters cover a variety of topics including the role of estrogen and progesterone, animal models, parameters for assessing endometrial receptivity, the mechanism of angiogenesis, epigenetic regulation, and stem/progenitor cells. Despite nearly 35 years of experience with in vitro fertilization, the rate of successful implantations remains low. Abnormal endometrial receptivity has been proposed as one of the factors contributing to reduced reproductive potential in women, but our understanding of it is limited. Endometrial receptivity results from an orchestrated interplay between the embryo and the maternal endometrium, and the receptive status, known as the window of implantation, is reached only briefly in the mid-luteal phase. This book provides a comprehensive overview of the latest advances in endometrial function and paves the way for innovative treatments and drug development for infertility. This work will appeal to a wide readership, from researchers on endometrial function and assisted reproductive technology (ART) to clinicians and technicians in the field of gynecology.
The Endometrium
Author | : Stanley R. Glasser,John D. Aplin,Linda C. Giudice,Siamak Tabibzadeh |
Publsiher | : CRC Press |
Total Pages | : 1079 |
Release | : 2002-05-16 |
Genre | : Medical |
ISBN | : 9780203219034 |
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The Endometrium is devoted to a comprehensive multi-disciplinary account of the uterine endometrium. This book is the first to define the regulatory biological interrelationships between epithelial and stromal cell phenotypes, endothelial cells, extracellular matrix and immunobiological elements. It highlights their relevance to clinical conditions
Molecular Genetics of Endometrial Carcinoma
Author | : Lora Hedrick Ellenson |
Publsiher | : Springer |
Total Pages | : 281 |
Release | : 2016-12-01 |
Genre | : Medical |
ISBN | : 9783319431390 |
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This comprehensive text provides a much-needed review of a disease that is currently garnering the interest of molecular biologists, translational scientists, and clinicians. The volume includes emerging developments in the molecular genetics of endometrial carcinoma. In addition to covering the basic genetics of endometrial carcinoma, chapters also cover a wide range of signaling pathways implicated in endometrial carcinoma. A section of the book includes a number of genetically engineered mouse models, which contribute to understanding the role of various genetic alterations in the development and progression of endometrial carcinoma. These models also provide preclinical models for developing effective targeted therapeutic approaches. Endometrial carcinoma is the most common malignancy of the female genital tract in the United States and the number of cases continues to increase around the world. This book is a meant to serve as a resource for a wide range of scientists, from molecular geneticists to signal transduction biologists, as well as to both clinicians and scientists interested in developing targeted therapeutic approaches for women with endometrial carcinoma.
Modern Medical Genetics and Genomics
Author | : Israel Gomy |
Publsiher | : BoD – Books on Demand |
Total Pages | : 106 |
Release | : 2019-12-18 |
Genre | : Medical |
ISBN | : 9781839681424 |
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The field of medical genetics and genomics has been constantly revolutionized by new breakthroughs, which bring more knowledge into the etiology and help improve the health care of individuals with either rare or common diseases. Nevertheless, as technologies evolve, novel challenges emerge, both technically and ethically, so they must be prudentially addressed. Among the myriad applications of genomics in medicine, this book depicts a glimpse of the advances achieved that have been leading us to the personalized/precision medicine era.
The Endometrial Factor
Author | : Carlos Simón,Linda C. Giudice |
Publsiher | : CRC Press |
Total Pages | : 557 |
Release | : 2017-04-27 |
Genre | : Medical |
ISBN | : 9781351647519 |
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At the dawn of precision medicine, there is a new opportunity for novel approaches to understand, diagnose and treat endometrial disorders that affect fertility, reproductive outcomes, and women’s health more broadly. Herein, the editors have assembled critically evaluated state-of-the-art chapters presenting basic and clinical knowledge about the human endometrium that impacts or will impact clinical practice. All clinicians and researchers in Reproductive Medicine will find this book useful as a reference and a valuable tool for continued advancement in the understanding and management of the "endometrial factor".
Proceedings from the Fourth International Conference on IUDs
Author | : C. Wayne Bardin,Daniel R. Mishell |
Publsiher | : Butterworth-Heinemann |
Total Pages | : 360 |
Release | : 1994 |
Genre | : Health & Fitness |
ISBN | : UOM:39015032940572 |
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The ART of Understanding ENDOMETRIUM
Author | : Onder CELIK,Cihat UNLU,I. Ipek MUDERRIS,Nilufer CELIK |
Publsiher | : Akademisyen Kitabevi |
Total Pages | : 82 |
Release | : 2020-05-03 |
Genre | : Medical |
ISBN | : 9786052587966 |
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