Epilepsy Surgery The Emerging Field Of Neuromodulation An Issue Of Neurosurgery Clinics

In this issue of Neurosurgery Clinics, Drs. Chang and Barbaro provide a thorough look at epilepsy, with sections focusing on devices in epilepsy surgery, open loop systems, closed loop systems, and non-stimulation. Topics in this issue include history and overview of stimulation for epilepsy, trigeminal nerve stimulation, anterior thalamus DBS, hippocampal stimulation, neuropace RNS, seizure detection/prediction algorithms, cooling, seizure prediction and its applications, stimulation paradigms, and experimental stimulation.

In this issue of Neurosurgery Clinics, Drs. Chang and Barbaro provide a thorough look at epilepsy, with sections focusing on devices in epilepsy surgery, open loop systems, closed loop systems, and non-stimulation. Topics in this issue include history and overview of stimulation for epilepsy, trigeminal nerve stimulation, anterior thalamus DBS, hippocampal stimulation, neuropace RNS, seizure detection/prediction algorithms, cooling, seizure prediction and its applications, stimulation paradigms, and experimental stimulation.

In this issue of Neurosurgery Clinics, guest editors Drs. Jimmy Yang and R. Mark Richardson bring their considerable expertise to the topic of Epilepsy Surgery: Paradigm Shifts. Top experts in the field explore the underutilization of epilepsy surgery as a public health crisis, and recent paradigm shifts in how epilepsy surgery is conceptualized that may help bring significant improvement to greater numbers of people with drug-resistant epilepsy. Contains 16 relevant, practice-oriented topics, including pediatric neurostimulation and practice evolution; brain stimulation in pediatric generalized epilepsy; imaging and SEEG functional networks to guide epilepsy surgery; sensing-enabled deep brain stimulation in epilepsy; thalamic stimulation to prevent impaired consciousness; gene therapy for epilepsy; and more. Provides in-depth clinical reviews on paradigm shifts in epilepsy surgery, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Electromyography remains a main diagnostic tool within neurology. This issue of Neurologic Clinics addresses the most recent developments in the clinical application of EMG. Articles in this issue include: Nerve conduction studies: Basic Concepts and Patterns of Abnormalities; Needle Electromyography–Basic Concepts andInterpretation of Recorded Potentials;Electrodiagnostic Evaluation of Carpal TunnelSyndrome;Electrodiagnostic Evaluation of Ulnar Neuropathyand Other Upper Extremity Mononeuropathy; Lower Extremity Mononeuropathies;Electrodiagnostic Evaluation of Brachial Plexopathies; Evaluation ofRadiculopathies;Electrodiagnostic Approach to Motor NeuronDiseases;Electrophysiologic Findings in PeripheralNeuropathies; Evaluation of Neuromuscular Junction Disorders in the EMGLaboratory;Electrodiagnostic Findings inMyopathy;Electrodiagnostic Approach to CranialNeuropathies; Technical Issues with Nerve Conduction Studies and Needle EMG;andCoding and Reimbursement of ElectrodiagnosticStudies.

Standard therapy for high grade glioma is a topic that is evolving, timely, and relevant. Guest Editors Isaac Yang, MD and Seunggu Han, MD have assembled a group of experts on management of high grade glioma. Some of the articles in this issue include: Use of language mapping to aid resection of eloquent gliomas; Clinical trials with immunotherapy; Clinical trials for small molecule inhibitors; Nanotechnology potential applications for GBM therapy; High Grade Gliomas in children; Modern Advances in Brain Tumor Treatments; Molecular pathways of Avastin interactions for the treatment of glioblastoma; and Quality of Life and Outcomes in Glioblastoma management.

Standard therapy for high grade glioma is a topic that is evolving, timely, and relevant. Guest Editors Isaac Yang, MD and Seunggu Han, MD have assembled a group of experts to highlight the latest updates on various forms of management of high grade glioma. Some of the articles included in this issue focus on Extent of Resection for Glioblastoma; Role of adjuvant radiation therapy; Survival benefit of the Temozolomide protocol; Alternative chemotherapeutic agents; The role of avastin; Radiology; Pseuodprogression and Treatment effect; Pathology; Medical Management; Management of insular gliomas; Use of motor mapping; GBM treatment with clinical trials for surgical resection; Clinical trials with immunotherapy; Clinical trials for small molecule inhibitors; Future role of CED for GBM treatment; Application of a vault nanoparticle therapy for GBM therapy; Management of high grade gliomas in pediatric populations; Targeting Glioma Stem Like Cells with a focus on CD 133; and Potential Role for STAT3 inhibitors in glioblastoma.

Guest Editors Rafael J. Tamargo and Judy Huang have focused on “Cranial Arteriovenous Malformations (AVMs) and Dural Arteriovenous Fistulas (DAVFs) in this issue of Neurosurgery Clinics of North America. Articles in this issue include: Arteriovenous Malformations: Epidemiology and Clinical Presentation; Dural Arteriovenous Fistulas: Epidemiology and Clinical Presentation; Historical Perspective of Treatments of Arteriovenous Malformations and Dural Arteriovenous Fistulas; Imaging of Arteriovenous Malformations and Dural Arteriovenous Fistulas; Classification Schemes for Arteriovenous Malformations; Classification Schemes for Dural Arteriovenous Fistulas; Acute Management of Ruptured Arteriovenous Malformations and Dural Arteriovenous Fistulas; Selection of Treatment Modalities or Observation of Arteriovenous Malformations; Selection of Treatment Modalities or Observation of Dural Arteriovenous Malformations; Surgical Treatment of Cranial Arteriovenous Malformations and Dural Arteriovenous Fistulas; Anesthesia Considerations and Intraoperative Monitoring During Surgery for Arteriovenous Malformations and Dural Arteriovenous Fistulas; Stereotactic Radiosurgery of Cranial Arteriovenous Malformations and Dural Arteriovenous Fistulas; Endovascular Treatment of Cranial Arteriovenous Malformations and Dural Arteriovenous Malformations; Occlusive Hyperemia Versus Normal Perfusion Pressure Breakthrough after Treatment of Cranial Arteriovenous Malformations; Vein of Galen Malformations: Epidemiology, Clinical Presentation, and Management; Carotid Cavernous Fistulas: Epidemiology, Clinical Presentation, and Management.