Essentials Of Carbohydrate Chemistry And Biochemistry

Concise yet complete, this is a succinct introduction to the topic, covering both basic chemistry as well as such advanced topics as high-throughput analytics and glycomics -- in one handy volume. This improved and expanded 3rd edition features all-new material on combinatorial synthesis of carbohydrates and carbohydrate biodiversity, and each chapter now contains study questions for self-learning and classroom teaching. Didactically written by an experienced lecturer and graduate student advisor, the text is backed by practical examples and more than 150 study questions tailored to students' needs.

Carbohydrates are the most abundant natural products, in line with their role as energy stores and structural building blocks in plants and algae. They are versatile enough to serve as encoders of biological information and, last but not least, they are involved in a variety of molecular recognition processes. Research into carbohydrate and glycoconjugate functions in cell-to-cell communication processes has even created a new and rapidly developing field of study: glycobiology. Thisbe Lindhorst's successful book is now available in its second edition. Going from the basic concepts right up to the most recent results, this didactically written book features numerous practical examples of synthetic and analytical methods. The contents have been thoroughly updated, and a new chapter on mass spectroscopy of carbohydrates has been added. With its clear and lucid style, this introduction to carbohydrate chemistry and biochemistry is essential reading for students and postgraduate scientists in chemistry, biochemistry, pharmacy and biomedicine. "a very readable book which presents carbohydrate chemistry and, in later sections, biochemistry as exciting areas to work and study. The author captures a sense of wonder and inspiration from the very elegance of these areas of science and their application in the real worlds of pharmaceutical and medical research." (The Alchemist)

This is the first broad treatment of carbohydrate chemistry in many years, and presents the structures, reactions, modifications, and properties of carbohydrates. Woven throughout the text are discussions of biological properties of carbohydrates, their industrial applications, and the history of the field of carbohydrate chemistry. Written for students as well as practising scientists, this textbook and handy reference will be of interest to a wide range of disciplines: biochemistry, chemistry, food and nutrition, microbiology, pharmacology, and medicine.

Carbohydrates play important roles in biological systems as energy sources, as structural materials, and as informational structures (when they are often attached to proteins or lipids). Their chemical reactivity and conformational behaviour is governed by mechanistic and stereochemical rules.

Thisbe K. Lindhorst Essentials of Carbohydrate Chemistry and Biochemistry Carbohydrates are probably nature’s most common product. Plants and algae biosynthesize millions of tons of them every year. Carbohydrates are stores of energy and structural building blocks; they are versatile enough to serve as encoders of biological information and, last but not least, they are involved in recognition processes at a molecular level. Research into carbohydrate and glycoconjugate functions in cell-to-cell communication processes has even created a new and rapidly developing field of study glycobiology Thisbe K. Lindhorst is one of the leading "next generation" scientists in the area of carbohydrate research. Within her current book she presents a comprehensive introduction to the fascinating world of carbohydrates. In a lucid, explicit language she explains carbohydrate structures and the basic concepts of saccharide chemistry and saccharide biochemistry. With the same clarity she spans the gap to the glycobiological aspects of modern "glyco-science". Sample descriptions of research methods supplement the vital teaching text and open an experienced scientist’s bag of tricks required to synthesize and analyze sugar derivatives easily and successfully. This book offers valuable guidance for students as well as for researchers working in chemistry, biochemistry and biomedicine. Reading it can help everyone become an expert in the field of carbohydrate chemistry.

Since its inception in 1945, this serial has provided critical and integrating articles written by research specialists that integrate industrial, analytical, and technological aspects of biochemistry, organic chemistry, and instrumentation methodology in the study of carbohydrates. The articles provide a definitive interpretation of the current status and future trends in carbohydrate chemistry and biochemistry.

The Carbohydrates: Chemistry and Biochemistry, Second Edition, Volume IA deals with the chemical and biochemical aspects of carbohydrates such as monosaccharides, sugars, esters, halogen derivatives, phosphates, glycosides, glycosans, alditols, and cyclitols. Topics range from carbohydrate chemistry and stereochemistry to the synthesis of naturally occurring monosaccharides, mutarotations and actions of acids and bases, conformations of sugars, and reactivity of saccharide hydroxyl groups toward esterification. This book consists of 15 chapters that explore the effects of ionizing radiations and autoxidation reactions, physical methods and methods of separation, nucleosides and antibiotics, and the biosynthesis of sugars and complex saccharides. The rapidly growing fields of glycolipids and glycoproteins are also discussed. In addition, the reader is introduced to halogen derivatives such as glycosyl halides and nonanomeric halides, along with the hydrolysis and synthesis of phosphates and other inorganic esters, determination of the structure of glycosides, and the physical and chemical properties of acyclic derivatives. The two final chapters cover the official nomenclature rules for carbohydrates and for enzymes having carbohydrates as substrates. This book will be of interest to chemists and biochemists.