Estrogen Effects on Traumatic Brain Injury

Estrogen Effects on Traumatic Brain Injury
Author: Kelli A Duncan
Publsiher: Academic Press
Total Pages: 172
Release: 2014-12-29
Genre: Science
ISBN: 9780128017074

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This book demystifies, deconstructs, and simultaneously humanizes the field of estrogen-mediated neuroprotection following TBI, making the subject approachable to both researchers and advanced students. Bringing together leading researchers and practitioners to explain the basis for their work, methods, and their results, chapters explore what is known about the role of estrogens following damage to the brain. With topics covering induction of estrogen response, consequences of estrogen action, and mechanisms underlying estrogen mediated neuroprotection, Estrogen Effects on Traumatic Brain Injury is of great importance to teachers, researchers, and clinicians interested in the role that estrogens play following traumatic brain injury. Written to provide a foundational view of estrogens as neuroprotectors in TBI, appropriate for both researchers and advanced students Data Analysis boxes in each chapter help with data interpretation and offer guidelines on how best to understand results. A multidisciplinary approach to the methods, issues, empirical findings in the field of estrogen mediated neuroprotection. Detailed focus on how studies relate and build upon each other and the ways different methods of analysis inform each other. Written to provide clinicians with new and developing treatment options for patients in their field.

Sex Hormones in Neurodegenerative Processes and Diseases

Sex Hormones in Neurodegenerative Processes and Diseases
Author: Gorazd Drevensek
Publsiher: BoD – Books on Demand
Total Pages: 360
Release: 2018-05-02
Genre: Medical
ISBN: 9781789230147

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The book provides chapters on sex hormones and their modulation in neurodegenerative processes and pathologies, from basic molecular mechanisms, physiology, gender differences, to neuroprotection and clinical aspects for potential novel pharmacotherapy approaches. The book contains 14 chapters written by authors from various biomedical professions, from basic researchers in biology and physiology to medicine and veterinary medicine, pharmacologists, psychiatrist, etc. Chapters sum up the past and current knowledge on sex hormones, representing original new insights into their role in brain functioning, mental disorders and neurodegenerative diseases. The book is written for a broad range of audience, from biomedical students to highly profiled medical specialists and biomedical researchers, helping them to expand their knowledge on sex hormones in neurodegenerative processes and opening new questions for further investigation.

On the Basis of Sex Impact on Traumatic Brain Injury

On the Basis of Sex  Impact on Traumatic Brain Injury
Author: T. John Wu,Courtney L. Robertson,Aviva Jane Symes,Peter John Crack
Publsiher: Frontiers Media SA
Total Pages: 180
Release: 2021-10-01
Genre: Medical
ISBN: 9782889711574

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Translational Research in Traumatic Brain Injury

Translational Research in Traumatic Brain Injury
Author: Daniel Laskowitz,Gerald Grant
Publsiher: CRC Press
Total Pages: 412
Release: 2015-12-01
Genre: Medical
ISBN: 9781498766579

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Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the development of new diagnostic and therapeutic approaches has been disappointingly slow. Translational Research in Traumatic Brain Injury attempts to integrate expertise from across specialties to address knowledge gaps in the field of TBI. Its chapters cover a wide scope of TBI research in five broad areas: Epidemiology Pathophysiology Diagnosis Current treatment strategies and sequelae Future therapies Specific topics discussed include the societal impact of TBI in both the civilian and military populations, neurobiology and molecular mechanisms of axonal and neuronal injury, biomarkers of traumatic brain injury and their relationship to pathology, neuroplasticity after TBI, neuroprotective and neurorestorative therapy, advanced neuroimaging of mild TBI, neurocognitive and psychiatric symptoms following mild TBI, sports-related TBI, epilepsy and PTSD following TBI, and more. The book integrates the perspectives of experts across disciplines to assist in the translation of new ideas to clinical practice and ultimately to improve the care of the brain injured patient.

Nutrition and Traumatic Brain Injury

Nutrition and Traumatic Brain Injury
Author: Institute of Medicine,Food and Nutrition Board,Committee on Nutrition, Trauma, and the Brain
Publsiher: National Academies Press
Total Pages: 444
Release: 2011-07-01
Genre: Medical
ISBN: 9780309210089

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Traumatic brain injury (TBI) accounts for up to one-third of combat-related injuries in Iraq and Afghanistan, according to some estimates. TBI is also a major problem among civilians, especially those who engage in certain sports. At the request of the Department of Defense, the IOM examined the potential role of nutrition in the treatment of and resilience against TBI.

Brain Injury

Brain Injury
Author: Robert S.B. Clark,Patrick Kochanek
Publsiher: Springer Science & Business Media
Total Pages: 384
Release: 2012-12-06
Genre: Medical
ISBN: 9781461517214

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Brain Injury is the second volume in the book series, Molecular and Cellular Biology of Critical Care Medicine. In this volume, a group of internationally regarded experts in important areas of neuroscience and neurointensive care research address the molecular and cellular basis of acute brain injury. This text covers acute brain injury within a context relevant to the care of patients with critical neurologic injuries such as cardiac arrest, trauma and stroke. It includes recent data pertaining to established pathways such as neurotransmission, exitotoxicity, ionic-mechanisms, oxidative stress, inflammation, and cerebral vascular injury. In addition, rapidly developing areas such as cell signaling, adenosine pharmacology, apoptosis, mitochondrial dysfunction, neurocytoskeletal changes, and the role of trophic factors are reviewed from the level of in vitro modeling to human data. Other topics covered that are highly clinically relevant include the effect of genetic background and gender differences in outcome after brain injury, preconditioning, and the effects of currently used anesthetics and sedative agents in patients with brain injury.

Brain Edema XII

Brain Edema XII
Author: T. Kuroiwa,A. Baethmann,Z. Czernicki,J.T. Hoff,U. Ito,Y. Katayama,A. Marmarou,D. Mendelow,H.-J. Reulen
Publsiher: Springer Science & Business Media
Total Pages: 612
Release: 2012-12-06
Genre: Medical
ISBN: 9783709106518

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Brain edema is a simple phenomenon – an abnormal increase of brain tissue volume by the increase of brain tissue water content. However the etiology is not simple and relating to a wide variety of neurological disorders including ischemia, trauma, tumor, hemorrhage and hydrocephalus. It is still a major cause of death in the neurological/neurosurgical ward. This volume is an up-to-date report on progress in brain edema research, diagnosis and treatment, including papers presented at the 12th International Symposium on Brain Edema and Brain Tissue Injury in 2002. Major topics include molecular biology and blood-brain barrier disorders, ischemic and traumatic brain edema, imaging and diagnosis of brain edema, treatment and radiation effect. Various papers in the rapidly growing fields of neuroimaging and molecular medicine are also included.

Traumatic Brain Injury

Traumatic Brain Injury
Author: Mark J. Ashley,David A. Hovda
Publsiher: CRC Press
Total Pages: 768
Release: 2017-07-28
Genre: Medical
ISBN: 9781498710329

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The fourth edition of this text constitutes a continuation of 20 years of coverage of traumatic brain injury, and broadens the discussion of acquired brain injury. Within TBI, the paradigm shift from an injury occurring at a point in time to a disease entity of a chronic nature is changing the discussion of diagnosis, management, treatment and outcome assessment. Disease specification that differentiates TBIs by the mechanism of injury, the exact nature of the injury, the extent of injury, presence of co-morbidities and their exact nature, gender, age, race, and genome are emerging as crucial. Disease differentiation has impacted diagnosis, treatment and outcome.