Explorations Of Mathematical Models In Biology With Matlab

Explore and analyze the solutions of mathematical models from diverse disciplines As biology increasingly depends on data, algorithms, and models, it has become necessary to use a computing language, such as the user-friendly MapleTM, to focus more on building and analyzing models as opposed to configuring tedious calculations. Explorations of Mathematical Models in Biology with Maple provides an introduction to model creation using Maple, followed by the translation, analysis, interpretation, and observation of the models. With an integrated and interdisciplinary approach that embeds mathematical modeling into biological applications, the book illustrates numerous applications of mathematical techniques within biology, ecology, and environmental sciences. Featuring a quantitative, computational, and mathematical approach, the book includes: Examples of real-world applications, such as population dynamics, genetics, drug administration, interacting species, and the spread of contagious diseases, to showcase the relevancy and wide applicability of abstract mathematical techniques Discussion of various mathematical concepts, such as Markov chains, matrix algebra, eigenvalues, eigenvectors, first-order linear difference equations, and nonlinear first-order difference equations Coverage of difference equations to model a wide range of real-life discrete time situations in diverse areas as well as discussions on matrices to model linear problems Solutions to selected exercises and additional Maple codes Explorations of Mathematical Models in Biology with Maple is an ideal textbook for undergraduate courses in mathematical models in biology, theoretical ecology, bioeconomics, forensic science, applied mathematics, and environmental science. The book is also an excellent reference for biologists, ecologists, mathematicians, biomathematicians, and environmental and resource economists.

This book is based on a one semester course that the authors have been teaching for several years, and includes two sets of case studies. The first includes chemostat models, predator-prey interaction, competition among species, the spread of infectious diseases, and oscillations arising from bifurcations. In developing these topics, readers will also be introduced to the basic theory of ordinary differential equations, and how to work with MATLAB without having any prior programming experience. The second set of case studies were adapted from recent and current research papers to the level of the students. Topics have been selected based on public health interest. This includes the risk of atherosclerosis associated with high cholesterol levels, cancer and immune interactions, cancer therapy, and tuberculosis. Readers will experience how mathematical models and their numerical simulations can provide explanations that guide biological and biomedical research. Considered to be the undergraduate companion to the more advanced book "Mathematical Modeling of Biological Processes" (A. Friedman, C.-Y. Kao, Springer – 2014), this book is geared towards undergraduate students with little background in mathematics and no biological background.

Explore and analyze the solutions of mathematical models from diverse disciplines As biology increasingly depends on data, algorithms, and models, it has become necessary to use a computing language, such as the user-friendly MATLAB, to focus more on building and analyzing models as opposed to configuring tedious calculations. Explorations of Mathematical Models in Biology with MATLAB provides an introduction to model creation using MATLAB, followed by the translation, analysis, interpretation, and observation of the models. With an integrated and interdisciplinary approach that embeds mathematical modeling into biological applications, the book illustrates numerous applications of mathematical techniques within biology, ecology, and environmental sciences. Featuring a quantitative, computational, and mathematical approach, the book includes: Examples of real-world applications, such as population dynamics, genetics, drug administration, interacting species, and the spread of contagious diseases, to showcase the relevancy and wide applicability of abstract mathematical techniques Discussion of various mathematical concepts, such as Markov chains, matrix algebra, eigenvalues, eigenvectors, first-order linear difference equations, and nonlinear first-order difference equations Coverage of difference equations to model a wide range of real-life discrete time situations in diverse areas as well as discussions on matrices to model linear problems Solutions to selected exercises and additional MATLAB codes Explorations of Mathematical Models in Biology with MATLAB is an ideal textbook for upper-undergraduate courses in mathematical models in biology, theoretical ecology, bioeconomics, forensic science, applied mathematics, and environmental science. The book is also an excellent reference for biologists, ecologists, mathematicians, biomathematicians, and environmental and resource economists.

This introductory textbook on mathematical biology focuses on discrete models across a variety of biological subdisciplines. Biological topics treated include linear and non-linear models of populations, Markov models of molecular evolution, phylogenetic tree construction, genetics, and infectious disease models. The coverage of models of molecular evolution and phylogenetic tree construction from DNA sequence data is unique among books at this level. Computer investigations with MATLAB are incorporated throughout, in both exercises and more extensive projects, to give readers hands-on experience with the mathematical models developed. MATLAB programs accompany the text. Mathematical tools, such as matrix algebra, eigenvector analysis, and basic probability, are motivated by biological models and given self-contained developments, so that mathematical prerequisites are minimal.

Mathematical Modeling in Biology: A Research Methods Approach is a textbook written primarily for advanced mathematics and science undergraduate students and graduate-level biology students. Although the applications center on ecology, the expertise of the authors, the methodology can be imported to any other science, including social science and economics. The aim of the book, beyond being a useful aid to teaching and learning the core modeling skills needed for mathematical biology, is to encourage students to think deeply and clearly about the meaning of mathematics in science and to learn significant research methods. Most importantly, it is hoped that students will experience some of the excitement of doing research. Features Minimal pre-requisites beyond a solid background in calculus, such as a calculus I course. Suitable for upper division mathematics and sciences students and graduate-level biology students. Provides sample MATLAB codes and instruction in Appendices along with datasets available on https://bit.ly/3fcLF3D

This book on mathematical modeling of biological processes includes a wide selection of biological topics that demonstrate the power of mathematics and computational codes in setting up biological processes with a rigorous and predictive framework. Topics include: enzyme dynamics, spread of disease, harvesting bacteria, competition among live species, neuronal oscillations, transport of neurofilaments in axon, cancer and cancer therapy, and granulomas. Complete with a description of the biological background and biological question that requires the use of mathematics, this book is developed for graduate students and advanced undergraduate students with only basic knowledge of ordinary differential equations and partial differential equations; background in biology is not required. Students will gain knowledge on how to program with MATLAB without previous programming experience and how to use codes in order to test biological hypothesis.

This book helps the reader make use of the mathematical models of biological phenomena starting from the basics of programming and computer simulation. Computer simulations based on a mathematical model enable us to find a novel biological mechanism and predict an unknown biological phenomenon. Mathematical biology could further expand the progress of modern life sciences. Although many biologists are interested in mathematical biology, they do not have experience in mathematics and computer science. An educational course that combines biology, mathematics, and computer science is very rare to date. Published books for mathematical biology usually explain the theories of established mathematical models, but they do not provide a practical explanation for how to solve the differential equations included in the models, or to establish such a model that fits with a phenomenon of interest. MATLAB is an ideal programming platform for the beginners of computer science. This book starts from the very basics about how to write a programming code for MATLAB (or Octave), explains how to solve ordinary and partial differential equations, and how to apply mathematical models to various biological phenomena such as diabetes, infectious diseases, and heartbeats. Some of them are original models, newly developed for this book. Because MATLAB codes are embedded and explained throughout the book, it will be easy to catch up with the text. In the final chapter, the book focuses on the mathematical model of the proneural wave, a phenomenon that guarantees the sequential differentiation of neurons in the brain. This model was published as a paper from the author’s lab (Sato et al., PNAS 113, E5153, 2016), and was intensively explained in the book chapter “Notch Signaling in Embryology and Cancer”, published by Springer in 2020. This book provides the reader who has a biological background with invaluable opportunities to learn and practice mathematical biology.