Exposed By Dna

Exposed By DNA: A Path to Reveal Family Secrets is a twist and turn adventure after the discovery of shocking results from an Ancestry DNA test. One family, siblings with different DNA? It will keep you wanting to know what happens next. An innocent love letter written in 1954 started a chain of events that prompted an exploration of the dates of paternity for my sister Lucy. Never in a million years would I have thought that my, and all my siblings' DNA would be in question. Science, in this case, has revealed what our parents never told us. Unless we do DNA testing, do we know where we actually come from? Is family history being rewritten for families because of a little test called DNA? My family history changed. What I was told and believed growing up was half the truth. With the use of many DNA sites, including Ancestry.com; 23andMe; GEDmatch.com (the site that helped identify the "Golden State Killer" suspect); FTDNA; and My Heritage, I have been able to map my own DNA.In this book I describe, in layperson's language, the process of mapping my DNA to reveal new family connections while searching for the truth

Using genealogy to discover his family’s secrets, Steve Anderson uncovers the uncomfortable truth about his biology and the questions it raised for his eight siblings and him. Like many people using new DNA technologies today, Anderson is shocked by his findings and determined to uncover how the truth of one’s biology can impact lives and relationships.

Toxicoepigenetics: Core Principles and Applications examines the core aspects of epigenetics, including chromatin biology, DNA methylation, and non-coding RNA, as well as fundamental techniques and considerations for studying each of these mechanisms of epigenetic regulation. Although its integration into the field of toxicology is in its infancy, epigenetics have taken center stage in the study of diseases such as cancer, diabetes, and neurodegeneration. Increasing the presence of epigenetics in toxicological research allows for a more in-depth understanding of important aspects of toxicology such as the role of the environment and lifestyle influencing the individual susceptibility to these effects and the trans-generational transmission of these health effects and susceptibilities. Methods chapters are included to help improve efficacy and efficiency of protocols in both the laboratory and the classroom. Toxicoepigenetics: Core Principles and Applications is an essential book for researchers and academics using epigenetics in toxicology research and study. Introduces the fundamental principles and practices for understanding the role of the epigenome in toxicology Presents the foundation of epigenetics for toxicologists with a broad range of backgrounds Discusses the incorporation of epigenetics and epigenomics into current toxicological studies and interpretation of epigenetic data in toxicological applications

DNA Repair and Cancer Therapy: Molecular Targets and Clinical Applications, Second Edition provides a comprehensive and timely reference that focuses on the translational and clinical use of DNA repair as a target area for the development of diagnostic biomarkers and the enhancement of cancer treatment. Experts on DNA repair proteins from all areas of cancer biology research take readers from bench research to new therapeutic approaches. This book provides a detailed discussion of combination therapies, in other words, how the inhibition of repair pathways can be coupled with chemotherapy, radiation, or DNA damaging drugs. Newer areas in this edition include the role of DNA repair in chemotherapy induced peripheral neuropathy, radiation DNA damage, Fanconi anemia cross-link repair, translesion DNA polymerases, BRCA1-BRCA2 pathway for HR and synthetic lethality, and mechanisms of resistance to clinical PARP inhibitors. Provides a comprehensive overview of the basic and translational research in DNA repair as a cancer therapeutic target Includes timely updates from the earlier edition, including Fanconi Anemia cross-link repair, translesion DNA polymerases, chemotherapy induced peripheral neuropathy, and many other new areas within DNA repair and cancer therapy Saves academic, medical, and pharma researchers time by allowing them to quickly access the very latest details on DNA repair and cancer therapy Assists researchers and research clinicians in understanding the importance of the breakthroughs that are contributing to advances in disease-specific research

This study of macroeconomics combines treatment of opposing theories with a presentation of evidence to point the way toward a reconstructed macro research and policy programme.