Fetus And Neonate Physiology And Clinical Applications Volume 2 Breathing

This, the second in the Fetus and Neonate series, concentrates on breathing. The book is divided into sections on physiology, pathophysiology and clinical applications. Recent research and concepts about fetal breathing, the transitions at birth and the control of post-natal breathing are reviewed. The roles of pathophysiological processes in the aetiology of respiratory diseases are discussed and important new developments in diagnosis and treatment are reviewed. The book is written by international authorities in the field, who are active researchers in clinical and basic science as well as practitioners in this area of medicine. It will serve as a valuable source of information for those involved in research in perinatal breathing, or training in paediatrics, neonatology and obstetrics. It will also stimulate the interest of a wider range of health care professionals concerned with keeping abreast of new ideas in this important area of medicine.

During the mid- to late-twentieth century, study of the physiology of the developing fetus and newborn infant evolved rapidly to become a major discipline in the biomedical sciences. Initially of interest from a standpoint of function of the placenta and oxygenation of the fetus, the field advanced to explore both normal functional mechanisms as well as pathophysiologic aspects of their regulation. Examples include studying the role and regulation of circulatory vascular anatomic shunts in oxygenation, cardiac function, certain aspects of asphyxia in the fetus and newborn infant, the role of fetal “breathing” movements, cyclic electroencephalographic activity, and analysis of electronic monitoring of fetal heart rate variability and its significance. Included in this book are reminisces of several dozen individuals who played a vital role in these developments. Overall, this survey considers a number of aspects of the development of the science of fetal and neonatal physiology, and its role in the greatly improved care of pregnant women and their newborn infants. This book is published on behalf of the American Physiological Society by Springer. Access to APS books published with Springer is free to APS members.

This volume provides a thorough examination of breathing in the fetus and newborn, analyzing physiology, pathophysiology, and clinical applications. The authors review recent research into fetal breathing, transitional processes at birth, and control of post-natal breathing. They also discuss the role of pathophysiological processes in the etiology of respiratory disease, and explore important new developments in diagnosis and treatment.

The Fetus and Neonate is a series of practical, focused texts which concentrate on that critical period of human development, from late fetal to neonatal life. Each volume in the series examines a particular body system, looking at the physiological mechanisms which underlie the transition from intrauterine to extrauterine life, and the pathophysiological processes which may occur in this period. Each volume will consider the application of new basic scientific knowledge to the clinical situation. This series will be a valuable source of information to practitioners and postgraduate trainees in obstetrics, neonatology, paediatrics and reproductive medicine, as well as to basic scientists in these fields.

This second edition offers an expanded and updated history of the field of fetal and neonatal development, allowing readers to gain a comprehensive understanding of the biological aspects that contribute to the wellbeing or pathophysiology of newborns. In this concluding opus of a long and prominent career as a clinical scientist, Dr. Longo has invited new contributions from noted colleagues with expertise in various fields to provide a historical perspective on the impact of how modern concepts emerged in the field of fetal physiology and contributed to the current attention paid to the fetal origins of diseases in adults. In addition to new chapters on maternal physiology and complications during pregnancy, others trace the history of the Society for Reproductive Investigation, governmental funding of perinatal research, and major initiatives to support training in the new discipline of maternal fetal medicine, including the Reproductive Scientist Development program. The extensive survey provided by the author, who personally knew most of the pioneers in the field, offers a unique guide for all clinical and basic scientists interested in the history of – and future approaches to diagnosing and treating – pathologies that represent the leading causes of neonatal mortality and, far too often, life-long morbidity.

Offering the comprehensive, authoritative information needed for effective diagnosis, treatment, and management of sick and premature infants, Fetal and Neonatal Physiology, 6th Edition, is an invaluable resource for board review, clinical rounds, scientific research, and day-to-day practice. This trusted two-volume text synthesizes recent advances in the field into definitive guidance for today's busy practitioner, focusing on the basic science needed for exam preparation and key information required for full-time practice. It stands alone as the most complete text available in this complex and fast-changing field, yet is easy to use for everyday application. Offers definitive guidance on how to effectively manage the many health problems seen in newborn and premature infants. Contains new chapters on Pathophysiology of Genetic Neonatal Disease, Genetic Variants and Neonatal Disease, and Developmental Biology of Lung Stem Cells, as well as significantly revised chapters on Cellular Mechanisms of Neonatal Brain Injury, Neuroprotective Therapeutic Hypothermia, Enteric Nervous System Development and Gastrointestinal Motility, and Physiology of Twin-Twin Transfusion. Features 1,000 full-color diagrams, graphs and anatomic illustrations, 170+ chapters, and more than 350 global contributors. Includes chapters devoted to clinical correlation that help explain the implications of fetal and neonatal physiology, as well as clinical applications boxes throughout. Provides summary boxes at the end of each chapter and extensive cross-referencing between chapters for quick reference and review. Allows you to apply the latest insights on genetic therapy, intrauterine infections, brain protection and neuroimaging, and much more. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

In the later stages of gestation, fetal functions undergo increasing change and development, preparing the fetus for the transition to its postnatal environment. Rapid maturation is witnessed in breathing, swallowing, sensory functions, sleep, and many other processes, with corresponding behavioral changes. By 35 to 40 weeks of gestation, fetuses are capable of living ex utero without support, but it is increasingly appreciated that even infants born at between 35 and 36 weeks can suffer long-term consequences. This book, which complements the author’s previous volume on development of normal fetal movements during the first 25 weeks of gestation, discusses in detail the full range of behavioral phenomena observed during the final 15 weeks of gestation, with careful analysis of their mutual relationships. A key feature is the outstanding photographic material, difficult to obtain at this late stage, and the instructive graphs that are also included. The information provided will alert clinicians to deviations from the norm and to physiologic phenomena that can turn pathologic in infants born prematurely.​

For more than 45 years, Avery & MacDonald’s Neonatology has been the premier text on the pathophysiology and management of both preterm and full-term neonates, trusted by neonatologists, neonatology fellows, pediatricians, neonatal nurse practitioners, and ob/gyn practitioners worldwide. Continuing the tradition of excellence established by Drs. Gordon B. Avery and Mhairi G. MacDonald, this fully revised eighth edition features three new lead editors, numerous new chapters, reorganized and updated content, and an increased focus on global neonatology.