Formation And Fate Of Cell Organelles

Formation and Fate of Cell Organelles presents the proceedings of the symposia of the International Society for Cell Biology. Contributors offer their views on various aspects of the problem of spontaneous assembly, particularly how cellular structures arise from the component molecules. They consider whether all cellular organelles and cells, themselves, can arise by spontaneous assembly, or whether some regulation is involved and the mechanisms underlying such regulation. This book is organized into 16 chapters and begins with an overview of self-assembling systems of equal units and how they can be built efficiently, focusing on quasi-equivalence and helical waves on bacterial flagella. This text also discusses the differences in free energy of the molecules in their various states and the use of the free energy of a particular array of molecules to predict what arrays will form. The reader is introduced to intermolecular forces and how macromolecular lipid structures assemble in vitro, along with developments in the resolution of the spindle fibers of the mitotic apparatus. The book also looks into the mechanisms underlying the disposition of microtubules in plant cells during interphase and mitosis, and then concludes with a chapter on some studies dealing with cytoplasmic genes and cytoplasmic inheritance. This book is a valuable source of information for scientists and researchers engaged in fields ranging from cytology and biology to chemistry, pathology, and biophysics.

The first volume of the series, on "The Stability of the Differentiated State" received many favorable reviews from the scientific community. Many readers seem to agree with us that publication of topical volumes is a worthwhile alternative to periodic compilations of rather unrelated, though up-to-date reviews. Production of topical volumes is however, plagued with one great difficulty, that of "author synchronization". This difficulty explains the lag between volumes 1 and 2 of the series. Nevertheless we hope that the present volume will be appreciated as a valuable source of information on its central topic: How do cell organelles originate, and what mechanisms assure their continuity? Tübingen, Berlin, Zürich, \V. BEERMANN, J. REINERT, H. URSPRUNG, Heidelberg H. -W. HA GENS Contents Assembly, Continuity, and Exchanges in Certain Cytoplasmic Membrane Systems by W. GORDON WHALEY, MARIANNE DAUWALDER, aüd ]OYCE E. KEPHART 1 I. The Nature of the Membrane. . . . . . H. The Assembly of Membranes . . . . . . 5 III. The Growth and Transfer of Membranes. 6 A. The Nuclear Envelopc . . . 6 B. The Endoplasmic Reticulum 13 C. The Golgi Apparatus . 17 D. The Plasma Membrane 28 E. Vacuoles and Vesicles 31 IV. Concluding Remarks 37 References . . . . . 38 Origin and Continuity of Mitochondria by ROBERT BAXTER 1. Introduction . . . . . . . . . . . . . 46 H. Mitochondrial Biogenesis : thc Machincry 46 III. Limitations of Mitochondrial Autonomy 50 IV. The Replication of Mitochondria 53 V. Discussion and Conclusion 58 Referenccs . . . . . . . . . 59 Origin and Continuity of Plastids by \VILFRIED STUBBE 1. Introduction . . . . . . . . . . . . . 65 II. Arguments for the Continuity of Plastids .

Concepts of Biology is designed for the single-semester introduction to biology course for non-science majors, which for many students is their only college-level science course. As such, this course represents an important opportunity for students to develop the necessary knowledge, tools, and skills to make informed decisions as they continue with their lives. Rather than being mired down with facts and vocabulary, the typical non-science major student needs information presented in a way that is easy to read and understand. Even more importantly, the content should be meaningful. Students do much better when they understand why biology is relevant to their everyday lives. For these reasons, Concepts of Biology is grounded on an evolutionary basis and includes exciting features that highlight careers in the biological sciences and everyday applications of the concepts at hand.We also strive to show the interconnectedness of topics within this extremely broad discipline. In order to meet the needs of today's instructors and students, we maintain the overall organization and coverage found in most syllabi for this course. A strength of Concepts of Biology is that instructors can customize the book, adapting it to the approach that works best in their classroom. Concepts of Biology also includes an innovative art program that incorporates critical thinking and clicker questions to help students understand--and apply--key concepts.

The Biogenesis of Cellular Organelles represents a comprehensive summary of recent advances in the study of the biogenesis and functional dynamics of the major organelles operating in the eukaryotic cell. This book begins by placing the study of organelle biogenesis in a historical perspective by describing past scientific strategies, theories, and findings and relating these foundations to current investigations. Reviews of protein and lipid mediators important for organelle biogenesis are then presented, and are followed by summaries focused on the endoplasmic reticulum, Golgi, lysosome, nucleus, mitochondria, and peroxisome.