Functional Neuromarkers For Psychiatry

Functional Neuromarkers for Psychiatry explores recent advances in neuroscience that have allowed scientists to discover functional neuromarkers of psychiatric disorders. These neuromarkers include brain activation patterns seen via fMRI, PET, qEEG, and ERPs. The book examines these neuromarkers in detail—what to look for, how to use them in clinical practice, and the promise they provide toward early detection, prevention, and personalized treatment of mental disorders. The neuromarkers identified in this book have a diagnostic sensitivity and specificity higher than 80%. They are reliable, reproducible, inexpensive to measure, noninvasive, and have been confirmed by at least two independent studies. The book focuses primarily on the analysis of EEG and ERPs. It elucidates the neuronal mechanisms that generate EEG spontaneous rhythms and explores the functional meaning of ERP components in cognitive tasks. The functional neuromarkers for ADHD, schizophrenia, and obsessive-compulsive disorder are reviewed in detail. The book highlights how to use these functional neuromarkers for diagnosis, personalized neurotherapy, and monitoring treatment results. Identifies specific brain activation patterns that are neuromarkers for psychiatric disorders Includes neuromarkers as seen via fMRI, PET, qEEG, and ERPs Addresses neuromarkers for ADHD, schizophrenia, and OCD in detail Provides information on using neuromarkers for diagnosis and/or personalized treatment

While the brain is ruled to a large extent by chemical neurotransmitters, it is also a bioelectric organ. The collective study of Quantitative ElectroEncephaloGraphs (QEEG-the conversion of brainwaves to digital form to allow for comparison between neurologically normative and dysfunctional individuals), Event Related Potentials (ERPs - electrophysiological response to stimulus) and Neurotherapy (the process of actually retraining brain processes to) offers a window into brain physiology and function via computer and statistical analyses of traditional EEG patterns, suggesting innovative approaches to the improvement of attention, anxiety, mood and behavior. The volume provides detailed description of the various EEG rhythms and ERPs, the conventional analytic methods such as spectral analysis, and the emerging method utilizing QEEG and ERPs. This research is then related back to practice and all existing approaches in the field of Neurotherapy - conventional EEG-based neurofeedback, brain-computer interface, transcranial Direct Current Stimulation, and Transcranial Magnetic Stimulation - are covered in full. While it does not offer the breadth provided by an edited work, this volume does provide a level of depth and detail that a single author can deliver, as well as giving readers insight into the personl theories of one of the preeminent leaders in the field. Features & Benefits: Provide a holistic picture of quantitative EEG and event related potentials as a unified scientific field. Present a unified description of the methods of quantitative EEG and event related potentials. Give a scientifically based overview of existing approaches in the field of neurotherapy Provide practical information for the better understanding and treatment of disorders, such as ADHD, Schizophrenia, Addiction, OCD, Depression, and Alzheimer's Disease

New neuroimaging techniques are developing at a break neck pace-every academic journal contains glossy pictures of brain activity corresponding to a particular task emblazoned in glorious technicolor. Discoveries about brain function in psychiatric disorders have been made at an equally rapid rate. However, most books on the subject have been writt

This volume addresses one of the Holy Grails in Psychiatry, namely the evidence for and potential to adopt ‘Biomarkers’ for prevention, diagnosis, and treatment responses in mental health conditions. It meshes together state of the art research from international renowned pre-clinical and clinical scientists to illustrate how the fields of anxiety disorders, depression, psychotic disorders, and autism spectrum disorder have advanced in recent years.

This book explores in depth a wide range of functional biomaterials-based systems for drug, gene delivery, and biomedical aspects. The chapters cover newer technologies such as polymeric micelle, pH-responsive biomaterials, stimuli-responsive hydrogels, silk fibroin, inorganic biomaterials, synthetic biomaterials, 3D printed biomaterials, metallic biomaterials, ceramic and hybrid biomaterials. It also describes the theranostic approaches for cancer therapy, the biomaterials-based nanofibers scaffolds in tissue engineering, as well as the strategies applications of metallic biomaterials for the medical and dental prosthetic field. This newer and updated approach will be attractive for biomedical engineering students working on materials science in the development of novel drug delivery strategies. The book will be an important reference for researchers and professionals working on biomaterial research in the pharmaceutical and medical fields.

In this issue of Neurosurgery Clinics, guest editors Drs. Joshua M. Rosenow and Julie G. Pilitsis bring their considerable expertise to the topic of Pain Management. Because pain management often benefits from a multidisciplinary approach, this issue addresses how pain can be assessed and managed with and without medication (e.g., acupuncture, chiropractic medicine, mindfulness meditation) and procedures. Contains 15 relevant, practice-oriented topics including the multidisciplinary team in pain management; healthcare disparity in pain; nonopioid postoperative pain management; holistic therapy: what works and what does not; machine learning and pain outcomes; and more. Provides in-depth clinical reviews on pain management, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

While many fields such as e-learning, business, and marketing have taken advantage of the potential of gamification, the healthcare domain has just started to exploit this emerging trend, still in an ad-hoc fashion. Despite the huge potential of applying gamification on several topics of healthcare, there are scarce theoretical studies regarding methodologies, techniques, specifications, and frameworks. These applications must be examined further as they can be used to solve major healthcare-related challenges such as care plan maintenance, medication adherence, phobias treatment, or patient education. Handbook of Research on Solving Modern Healthcare Challenges With Gamification aims to share new approaches and methodologies to build e-health solutions using gamification and identifies new trends on this topic from pedagogical strategies to technological approaches. This book serves as a collection of knowledge that builds the theoretical foundations that can be helpful in creating sustainable e-health solutions in the future. While covering topics such as augmented and virtual reality, ethical issues in gamification, e-learning, telehealth services, and digital applications, this book is essential for research scholars, healthcare/computer science teachers and students pursuing healthcare/computer science-related subjects, enterprise developers, practitioners, researchers, academicians, and students interested in the latest developments and research solving healthcare challenges with modern e-health solutions using gamification.

Despite their opposite emotional effects, humor and horror are highly similar phenomena. They both can be traced back to (the detection, resolution, and emotional elaboration of) incongruities, understood as semantic violations through unexpected combinations of oppositional information. However, theoretical and experimental comparisons between humor and resolvable incongruities that elicit other emotions than exhilaration have been lacking so far. To gain more insights into the linguistic differences between humor and horror and the cognitive real-time processing of both, a main concern of this book is to discuss the transferability of linguistic humor theories to a systematic horror investigation and directly compare self-paced reading times (SPR), facial actions (FACS), and event-related brain potentials (ERP) of normed minimal quadruplets with frightening and humorous incongruities as well as (in)coherent stimuli. The results suggest that humor and horror share cognitive resources to detect and resolve incongruities. To better distinguish humor from neighboring phenomena, this book refines current humor theories by incorporating humor and horror in a cognitive incongruity processing model.