Functionalization Of Carborane Via Carboryne Intermediates

This thesis focuses on the development of new methods of functionalizing carboranes using o-carboryne intermediates. Functional carboranes are now finding a broad range of applications, including organic synthesis, drug design, polymers, catalysis, metal−organic frameworks, electronic devices and more. However, the limited number of efficient synthetic methods for obtaining functional carborane materials has restricted their applications. The methodologies established in this thesis represent simple, yet powerful strategies to assemble previously inaccessible, useful complex molecules, which will also have a significant impact on future synthetic, cluster and materials chemistry. Moreover, it discusses the first method for the in situ generation of electrophilic boron radical using photocatalysis.

Advances in Catalysis, Volume 71 highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Advances in the catalytic and photocatalytic behavior of carborane derived metal complexes, Transition metal catalyzed synthesis of derivatives of polyhedral boron hydrides with B-N, B-P, B-O and B-S bonds, Recent advances in transition metal catalyzed selective cage BH functionalization of o-carboranes, Boron Compounds for Catalytic Applications, Regioselective Carborane B-H/C-H Functionalization, and Derivatization of monocarborane and dodecaborate anions by controlled B–H activation. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in Advances in Catalysis serials Updated release includes the latest information on advances in the synthesis and catalytic applications of boron cluster

Advances in Heterocyclic Chemistry, Volume 126, is the definitive series in the field, one that is of great importance to organic chemists, polymer chemists and many biological scientists. Because biology and organic chemistry increasingly intersect, the associated nomenclature is used more frequently in explanations. Updates to this release include sections on The Literature of Heterocyclic Chemistry, Part XVI, 2016, The preparation and properties of heteroarylazulenes and hetero-fused azulenes, Recent developments in pyrazole chemistry, Yne, Ene-Yne Synthetic Approaches to Heterocycles, Appel Salt and Heterocycles: A review of Thirty Years of 4,5-Dichloro-1,2,3-dithiazolium Chloride Chemistry, and more. Written by established authorities in the field, this comprehensive review combines descriptive synthetic chemistry and mechanistic insight to yield an understanding on how chemistry drives the preparation and useful properties of heterocyclic compounds. Considered the definitive serial in the field of heterocyclic chemistry Serves as the go-to reference for organic chemists, polymer chemists and many biological scientists Provides timely, comprehensive reviews written by established authorities in the field Combines descriptive synthetic chemistry and mechanistic insight to enhance understanding on how chemistry drives the preparation and useful properties of heterocyclic compounds

Zaozao Qiu shows in this thesis that transition metals can mediate or catalyze the cycloaddition or coupling reactions of carboryne with alkynes or alkenes to afford benzocarboranes, alkenylcarboranes or dihydrobenzocarboranes. These results represent powerful strategies to assemble useful complex molecules from very simple precursors in a single operation. Carboranes have many applications in medicine. However, their unique structures make derivatization difficult and the limited efficient synthetic methods to obtain functional carborane materials have restricted applications of carboranes within a narrow scope. This work breaks a new ground in metal-carboryne chemistry and will have a significant impact on synthetic, cluster and materials chemistry.

A contemporary compilation of recent achievements inorganometallic chemistry The prestigious International Conference on OrganometallicChemistry (ICOMC) was launched in 1963, providing a forum forresearchers from around the world to share their findings andexplore new paths to advance our knowledge and application oforganometallic chemistry. The 25th ICOMC, held in Lisbon in 2012,gathered more than 1,200 participants from 54 countries. Thisvolume celebrates the 25th Silver Edition and the 50th Gold Year ofthe ICOMC. Featuring contributions from invited 25th ICOMC speakers,Advances in Organometallic Chemistry and Catalysishighlights recent achievements and new and emerging areas ofresearch in the field. Its seven sections cover: Activation and Functionalization of Carbon Single Bonds andSmall Molecules Organometallic Synthesis and Catalysis Organometallic Polymerization Catalysis Organometallic Polymers and Materials Organometallic Chemistry and Sustainable Energy Bioorganometallic Chemistry Organometallic Electrochemistry Chapters discuss fundamental underlying concepts, offerillustrative examples and cases, and explore future avenues forcontinued research. Readers will discover basic principles andproperties of organometallic compounds, reaction mechanisms, anddetailed descriptions of current applications. Collectively, thesechapters underscore the versatility, richness, and potential ofmodern organometallic chemistry, including its interrelationshipswith other scientific disciplines. All the contributions are extensively referenced, providing agateway to the most important original research papers and reviewsin organometallic chemistry. Presenting a contemporaryunderstanding of organometallic chemistry and its manyapplications, Advances in Organometallic Chemistry andCatalysis is recommended for all researchers in the field, fromstudents to advanced investigators.

Carboranes, Third Edition, by Russell Grimes, is the definitive resource on the subject. Completely updated with a wealth of research and review articles published in this active field since the previous volume was released in 2011, the book provides a readable and concise introduction to the basic principles underlying the synthesis, structures, and reactions of carboranes, heterocarboranes, and metallacarboranes. Following the valuable foundational information, the book explores the advances in practical applications for the many areas in which experts have discovered that carboranes afford new possibilities for solving problems and advancing the science. These disciplines include polymer science, catalysis, biomedicine, nanomaterials, and others. Includes over 2,000 molecular structure drawings throughout the text Features expanded coverage on applications of carboranes, particularly in biomedicine and nanomaterials, given the growth of research in these areas Presents extended and updated tables, listing thousands of compounds with key literature references, provided online via the book’s website Explores the advances in practical applications for the many areas in which experts have discovered that carboranes afford new possibilities for solving problems and advancing the science

Boron science features in numerous fields including organic chemistry, organometallic chemistry and medicine. Boron is unique in all aspects of science and engineering and has made a significant impact in our daily lives through its use in fertilizers, germicides, fungicides, soaps, detergents, cancer drugs as well as many household glassware utensils, ceramics and cell phone windows. These volumes bring together an array of internationally renowned scientists to discuss the very latest developments in the application of boron in a broad range of disciplines. This multi-reference work describes the topic by appointing leading researchers to write on current developments in boron science, showcasing its importance to the four separate areas described in each volume: Organometallic Chemistry, Catalysis, Materials Chemistry and Medicine.Written to cover the full range of applications and innovations in boron science, this all-encompassing work offers us a one-stop reference compiled by world-leading researchers and practitioners of the subject, making it perfect for undergraduate and graduate students of chemistry, and researchers and practitioners interested in their professional development.

Boron has made a significant impact in our lives through its quiet use in fertilizers, fungicides, soaps, detergents, and heat-resistant glassware. Boron Science: New Technologies and Applications addresses the applications of boron in chemistry, industry, medicine, and pharmacology by explaining its role in problems such as catalysis and hydroboration as well as its use in superconductors, materials, magnetic/nonmagnetic nanoparticles, and medical applications including cancer therapy. Illustrating the practical versatility of boron, the 29 chapters are divided into seven major sections: Boron for Living: Medicine Boron for Living: Health and Nutrition Boron for Living: Radioisotope Boron for Living: Boron Neutron Capture Therapy Boron for Electronics: Optoelectronics Boron for Energy: Energy Storage, Space, and Other Applications Boron for Chemistry and Catalysis: Catalysis and Organic Transformations More than just an updated compilation of progress in the applied science of boron, this book is a tribute to the legions of workers who have spent years conducting groundbreaking studies. The book celebrates these scientists and their protégés, who together transformed boron science into the exciting and growing area it is today.