Fundamentals Of Medical Biotechnology

"Biotechnology, an allied subject of biology, is also associated with its neighboring subject areas, such as: biochemistry, biophysics, biostatistics, pharmacology, cell biology, molecular biology, clinical biology, genomics and proteomics and nanotechnology, which makes this subject an advanced area in medical and health sciences. The exponential growth of the above fields in the past three decades, particularly information technology and biomedical technology and their myriad applications in medicine and health sciences, makes the field of biotechnology a potential front runner. The sophistication in biological techniques and methods makes biotechnological studies more precise, interesting, measurable and reproducible. Fundamentals of Medical Biotechnology is designed to cover all the areas of biotechnological advancement in cell biology, genetics, molecular biology, biochemistry, metabolism, microbiology, clinical pharmacology, immunology, biostatistics and bioinformatics. It helps students of biology, biotechnology, medical sciences and other health sciences to learn the advancement in the field of biomedicine and biotechnology. The book also covers the basics of diagnostic techniques in clinical biochemistry, specific to the technologies addressed in various chapters in the book, at both theoretical and application levels. The book focuses on why these techniques are useful in a clinical context and considers their potential uses, limitations and the ethical considerations that surround their use. This book is based on the recent development in the research dynamics of medical biotechnology, biochemistry and the progress in these fields. It also provides current reference material for students entering the field of medical and bioinformatics, academicians as well as research scientists. The book is a useful source of knowledge for students at senior secondary level, undergraduate and postgraduates in biotechnology and allied subjects, and MBBS / BDS level students looking for an accessible introduction of the subject"--

This book serves as an introduction to the concepts of medical biotechnology, with great details about fundamentals and early disciplines of study as well as emerging fields and the latest research. The book follows a chronological order from the earliest discoveries and breakthroughs of medical biotechnology to the latest areas of study. The book contains up-to-date citations for each chapter and section, which makes it easy for the reader to understand the concept and also to follow the latest developments in the particular area. It is an ideal book for undergraduate and graduate students who aspire to derive basic knowledge and are also keen on learning about the latest advancements in the field of medical biotechnology.

Intro -- Contents -- Preface -- Chapter 1 -- Medical Biotechnology: An Introduction -- Abstract -- 1. Introduction -- 2. MedicalBiotechnology: An Introduction -- 3. Recombinant DNA Technology -- 4. Genome Editing and Gene Therapy -- 5. Monoclonal Antibodies and Plantibodies -- 6. Vaccine Technology -- 7. In Silico Drug Designing -- 8. Human Genome Project -- 9. RNA Interference -- 10. Nano-Biotechnology and Nano-Medicine -- 11. Stem CellTherapy -- 12. Metamaterials -- Conclusion -- References -- Chapter 2 -- Medical Diagnostics -- Abstract -- 1. Introduction -- 1.1. What Is Medicine? -- 2. Medical Diagnosis: An Introduction -- 3. Diagnostic Process -- 3.1. The 'Diagnostic Process' Proceeds as Follows -- 4. Diagnosis vs. Prognosis -- 5. Diagnosis Test -- 5.1. RT-PCR for COVID-19 Diagnosis -- 5.2. AIDS Diagnosis by ELISA -- 5.2.1. Immunoglobulin (Ig)/Antibody -- 5.2.2. Antigen -- 5.3. Significance of Diagnostic Process -- 6. Phlebotomy -- 7. Computer Aided Diagnosis -- Conclusion -- References -- Chapter 3 -- Research Methodology of Medical Science "In Silico Analysis of GDF15 Using Gynecoinformatics" -- Abstract -- 1. Research Methodology and Gyneco Informatics: An Introduction -- 2. Methods -- 2.2. Model Reputation -- 3. Results and Discussion -- 3.1. The Building of Protein Model -- 3.2. Model Reputation -- 3.3. Model Validation -- Conclusion -- References -- Chapter 4 -- Nanomaterials: Synthesis, Characterization and Applications -- Abstract -- 1. Introduction -- 2. Nanoscience and Nanotechnology: Definition -- 2.1. Characteristics of Nanomaterials -- 3. Classification of Nanomaterials -- 3.1. Dimensions of Nanoparticles -- 3.2. Morphology of Nanomaterials -- 3.3. Chemical Composition of Nanomaterials -- 4. Synthesis of Nanomaterials -- 4.1. Top-Down Approach -- 4.2. Bottom-Up Approach -- 5. Characterization of Nanomaterials.

A single source reference covering every aspect of biotechnology, Biotechnology Fundamentals, Second Edition breaks down the basic fundamentals of this discipline, and highlights both conventional and modern approaches unique to the industry. In addition to recent advances and updates relevant to the first edition, the revised work also covers ethics in biotechnology and discusses career possibilities in this growing field. The book begins with a basic introduction of biotechnology, moves on to more complex topics, and provides relevant examples along the way. Each chapter begins with a brief summary, is illustrated by simple line diagrams, pictures, and tables, and ends with a question session, an assignment, and field trip information. The author also discusses the connection between plant breeding, cheese making, in vitro fertilization, alcohol fermentation, and biotechnology. Comprised of 15 chapters, this seminal work offers in-depth coverage of topics that include: Genes and Genomics Proteins and Proteomics Recombinant DNA Technology Microbial Biotechnology Agricultural Biotechnology Animal Biotechnology Environmental Biotechnology Medical Biotechnology Nanobiotechnology Product Development in Biotechnology Industrial Biotechnology Ethics in Biotechnology Careers in Biotechnology Laboratory Tutorials Biotechnology Fundamentals, Second Edition provides a complete introduction of biotechnology to students taking biotechnology or life science courses and offers a detailed overview of the fundamentals to anyone in need of comprehensive information on the subject.

The future is now—this groundbreaking textbook illustrates how biotechnology has radically changed the way we think about health care Biotechnology is delivering not only new products to diagnose, prevent, and treat human disease but entirely new approaches to a wide range of difficult biomedical challenges. Because of advances in biotechnology, hundreds of new therapeutic agents, diagnostic tests, and vaccines have been developed and are available in the marketplace. In this jargon-free, easy-to-read textbook, the authors demystify the discipline of medical biotechnology and present a roadmap that provides a fundamental understanding of the wide-ranging approaches pursued by scientists to diagnose, prevent, and treat medical conditions. Medical Biotechnology is written to educate premed and medical students, dental students, pharmacists, optometrists, nurses, nutritionists, genetic counselors, hospital administrators, and individuals who are stakeholders in the understanding and advancement of biotechnology and its impact on the practice of modern medicine. Hardcover, 700 pages, full-color illustrations throughout, glossary, index.

Molecular biotechnology continues to triumph, as this textbook testifies - edited by one of the academic pioneers in the field and written by experienced professionals. This completely revised second edition covers the entire spectrum, from the fundamentals of molecular and cell biology, via an overview of standard methods and technologies, the application of the various "-omics", and the development of novel drug targets, right up to the significance of system biology in biotechnology. The whole is rounded off by an introduction to industrial biotechnology as well as chapters on company foundation, patent law and marketing. The new edition features: - Large format and full color throughout - Proven structure according to basics, methods, main topics and economic perspectives - New sections on system biology, RNA interference, microscopic techniques, high throughput sequencing, laser applications, biocatalysis, current biomedical applications and drug approval - Optimized teaching with learning targets, a glossary containing around 800 entries, over 500 important abbreviations and further reading. The only resource for those who are seriously interested in the topic. Bonus material available online free of charge: www.wiley-vch.de/home/molecbiotech

The field of pharmaceutical biotechnology is evolving rapidly. A whole new arsenal of protein pharmaceuticals is being produced by recombinant techniques for cancer, viral infections, cardiovascular and hereditary disorders, and other diseases. In addition, scientists are confronted with new technologies such as polymerase chain reactions, combinatorial chemistry and gene therapy. This introductory textbook provides extensive coverage of both the basic science and the applications of biotechnology-produced pharmaceuticals, with special emphasis on their clinical use. Pharmaceutical Biotechnology serves as a complete one-stop source for undergraduate pharmacists, and it is valuable for researchers and professionals in the pharmaceutical industry as well.