Gastrointestinal Diseases And Their Associated Infections

Many bacteria, viruses, protozoa, and fungi play key roles in the development of gastrointestinal diseases, and this practical reference brings you up to speed with this increasingly important area. Covering a broad range of GI diseases and cancers, this resource provides an expert overview of the field, ideal for all gastroenterologists and infectious disease physicians. Covers infections associated with gastroesophageal reflux disease and Barrett’s esophagus, gallbladder disease, acute pancreatitis, small intestinal bacterial overgrowth, irritable bowel syndrome, inflammatory bowel disease, appendicitis, Whipple Disease, Crohn’s Disease, and more. Discusses esophageal cancer, gastric cancer, cholangiocarcinoma, hepatocellular carcinoma, and colorectal cancer. Includes chapters on gut microbiome, fecal transplants, and the molecular pathgenesis of gastrointestinal infections. Consolidates today’s available information on this timely topic into a single convenient resource.

Infections of the gastrointestinal (GI) system can be caused by many organisms, including bacteria, parasites, viruses and funghi. This manual is a practical guide providing gastroenterologists and infectious disease specialists with up to date knowledge on GI infections. Beginning with general topics including etiology and prevention, imaging and dietary management, the following chapters present different micro-organisms and the infections and diseases they may cause. The agents responsible for infection, diagnosis, clinical features and therapy for each syndrome are discussed in detail. This comprehensive text includes more than 300 full colour illustrations, slides and photographs, and contributions from experts in microbiology, pathology, histopathology and gastroenterology. Key points Practical guide to gastrointestinal infections Discusses many different micro-organisms and resulting infections and diseases Includes more than 300 illustrations, slides and photographs Contributions from experts in microbiology, pathology, histopathology and gastroenterology

Gastrointestinal diseases present a considerable problem in human medicine in terms of both morbidity and mortality. The aim of this book is to cover the different immunological disorders of the gut with special reference to immunopathological and protective mechanisms. It will be of general interest to clinicians, scientists and students concerned with the gastrointestinal tract. Topics covered include: the current status of research into toxin-secreting pathogens, Campylobacter, Giardia and HIV; the immunological features of idiopathic inflammatory gut diseases such as Crohn's disease and intractable diarrhoea; the genesis of the flat mucosa; the iatrogenic diseases of the gut such as graft-versus-host disease and small bowel allografts; the immune mechanisms and lesions in the gut of patients with parasitic nematode infections (very important in the tropics). Basic background on the immune apparatus in the intestine is also discussed, as are the effects of inflammation on intestinal permeability.

In this issue of Gastroenterology Clinics, Guest Editors M. Nedim. N. Ince and David E. Elliott bring their considerable expertise to the topic of Gastrointestinal Infections. Top experts in the field cover key topics such as Candida esophagitis, Acute bacterial gastroenteritis, Clostridium difficile infection and antibiotic-associated diarrhea, and more. Provides concise and comprehensive coverage of the issues physicians face every day. Presents the latest information on a timely, focused topic under the leadership of experienced editors in the field. Contains 14 relevant, practice-oriented topics including Helicobacter pylori infection; Viral gastroenteritis in special patient populations; Rare causes of hepatitis; Postinfectious irritable bowel syndrome; and more.

Enteric infection has played an important role in the majority of the world's populations, including children (particularly those under four years of age), the aged, the malnourished, military populations, and per sons from industrialized regions traveling to developing areas. The magni tude of the problem has been profound in areas of the world with reduced economic development, where there exists a greater reservoir of entero pathogens and a larger susceptible population with nutritional deficits. Morbidity from enteric infection in developing areas exceeds that seen in industrialized countries by severalfold, with the problem being most seri ous in infants who are bottle-fed and other infants and young children soon after being weaned from the breast ("weanling diarrhea"). Of greater significance than the inverse relationship of diarrhea morbidity with levels of industrial development is the relationship of death from intestinal infection and socioeconomic advancement. Mortality rate from diarrhea is 10 to 100 times greater in developing areas. In many parts of the third world, diarrhea, resultant dehydration, and associated malnutri tion are the leading causes of death in infants and young children and account for as great as one-third of pediatric deaths.

This issue focuses on the latest cutting-edge research in GI diseases that have or may have an infectious origin, including gallbladder disease, gastric cancer, inflammatory bowel disease and others.