Gastrointestinal Lymphoma

Gastrointestinal lymphomas have attracted increasing interest over the past few years and are a topic characterized by intensive and ongoing activity. Insights into their pathogenesis and biological behavior have expanded impressively. However, this increased understanding has also raised many new questions. Experts from all over the world came together to exchange their experiences and to discuss new concepts at an international symposium in Würzburg, Germany, in 1998. This book summarizes the presentations.

This is a comprehensive textbook of Hodgkin's and non-Hodgkin's lymphomas written by leaders in the field of childhood lymphomas. It includes clinical, pathologic and molecular biology of each subtype of lymphoma. The pathology chapters are comprehensive and include excellent photographs. The book is at the level of subspecialists in pediatric hematology and oncology, radiation oncology, pediatric surgery and hematopathology.

In 74 chapters, Gastrointestinal Oncology brings together a diverse group of specialists to provide the most authoritative, up-to-date and encyclopedic volume currently available on the subject. The first part of this text introduces a series of concepts and topics taht are important to gastrointestinal malignancies in general. These topics include epidemiologic principles, prevention, screening, familial GI cancers, developmental and molecular biology, pathobiology, general therapeutic principles, emerging therapies, and palliative care. The second part of the book covers each of the specific cancers affecting the human gastrointestinal tract. These chapters are introduced by state of the art discussions outlining our current understanding of the pathobiology and molecular biology relevant to each cancer. Subsequent sections describe the multidisciplinary management of specific clinical situations. By organizing the treatment-related chapters around clinical scenarios, the reader will readily find the information necessary to effectively manage the complex clinical situations encountered by patients with gastrointestinal malignancies.

Lymphomas classically manifest themselves in the lymph nodes but can also present in other bodily tissues or systems; the organ where exactly they present may make a very great difference to the strategy that should be adopted for their management. This topic has only recently been consistently addressed as an issue on its own, apart from the rest of the lymphomas, and this text is the first to apply modern systems of classification, diagnosis and management. This text is essential reading for hematologic oncologists and hematopathologists.

During the 10 years since the last edition of this volume our knowledge on malignant lymphomas, especially on extranodal lymphomas, has increased. This volume is an expanded and completely revised edition, now based on the WHO classification. The parallels to the updated Kiel classification and the REAL classification are indicated. The information is organized in organ-specific chapters, comprising the well-known nodal lymphoma entities as well as all known extranodal lymphomas and the different organ-specific clinico-pathological entities: lymphomas of the spleen, the gastrointestinal tract, the skin, etc. In addition to the morphology, the major immunohistochemical, molecular genetic, and clinical data are included in each chapter.

This book provides the most comprehensive and up-to-date knowledge of lymph node micrometastasis (LMM) and sentinel node navigation surgery (SNNS) in gastrointestinal cancers. Lymph node metastasis is a critically important prognostic factor in gastrointestinal tract cancers such as tumors of the esophagus, stomach, and colorectum. An understanding of the basic aspects of lymphatics and lymph nodes, including anatomy, histology, physiology, immunology, and molecular biology, is fundamental for physicians who are involved in cancer treatment. Furthermore, owing to the development of molecular and biological methodology, the precise recognition of LMM and its clinical significance have been clarified recently. At the same time, SNNS has actually been anticipated in treatment of breast tumors, and it is now being introduced in gastrointestinal tract cancer. For the application of SNNS, the detection of lymph node metastasis including LMM is extremely significant, because the presence of LMM determines the direction for surgery and chemo and/or radiation therapy. With these considerations in mind, the expert contributors to this book review basic and clinical approaches for LMM and SNNS including methodology for gastrointestinal cancers. Thus this volume benefits not only surgeons who treat gastrointestinal cancers but also clinical oncologists and medical scientists such as physiologists and pathologists.

A full and discursive account of lymphomas in tissues other than the lymph nodes. This book brings together into one volume information on extranodal lymphomas in all body systems and organs. It should help the reader with diagnosis and assessment, and the text includes details of clinical presentation and, where possible, prognosis. With hundreds of colour illustrations, this should serve as a vital bench book for the histopathologist, and should also provide the haematopathologist with a handy reference and literature review. Written by the experts, this is the first comprehensive account of the field.

Ideal for both trainees and experienced practitioners, Textbook of Gastrointestinal Radiology, 5th Edition, provides detailed, concise, well-illustrated information on all aspects of GI imaging—now in a single volume for convenient point-of-care reference. Drs. Richard M. Gore and Marc S. Levine lead a team of world-renowned experts to provide unparalleled coverage of all major gastrointestinal disorders as well as the complete scope of abdominal imaging modalities. Every chapter has been thoroughly updated, and new authors provide fresh perspectives on complex imaging topics. Offers streamlined, actionable content in a new single-volume format for quicker access at the point of care. Highlights the complete scope of imaging modalities including the latest in MDCT, MRI, diffusion weighted and perfusion imaging, ultrasound, PET/CT, PET/MR, plain radiographs, MRCP, angiography, barium studies, and CT and MR texture analysis of abdominal and pelvic malignancies. Features more than 1,100 state-of-the art-images, with many in full color. Discusses the imaging features of abdominal and pelvic malignancies that are key in an era of personalized medicine, as well as the relationship of abdominal and pelvic malignancies to cancer genomics and oncologic mutations that guide novel molecular, targeted and immunotherapies. Provides a diagnostic approach to incidentally discovered hepatic, pancreatic, and splenic lesions now commonly found on cross-sectional imaging.