Genetic Constraints On Adaptive Evolution

Genetic constraints on adaptive evolution can be understood as those genetic aspects that prevent or reduce the potential for natural selection to result in the most direct ascent of the mean phenotype to an optimum. The contributions to this volume emphasize how genetic aspects in the transmission of traits constrain adaptive evolution. Approaches span from quantitative, population, ecological to molecular genetics. Much attention is devoted to genetic correlations, to the maintenance of quantitative genetic variation, and to the intimate relation between genetics, ecology, and evolution. This volume addresses all evolutionary biologists and explains why they should be wary of evolutionary concepts that base arguments purely on phenotypic characteristics.

An enduring controversy in evolutionary biology is the genetic basis of adaptation. Darwin emphasized "many slight differences" as the ultimate source of variation to be acted upon by natural selection. In the early 1900’s, this view was opposed by "Mendelian geneticists", who emphasized the importance of "macromutations" in evolution. The Modern Synthesis resolved this controversy, concluding that mutations in genes of very small effect were responsible for adaptive evolution. A decade ago, Allen Orr and Jerry Coyne reexamined the evidence for this neo-Darwinian view and found that both the theoretical and empirical basis for it were weak. Orr and Coyne encouraged evolutionary biologists to reexamine this neglected question: what is the genetic basis of adaptive evolution? In this volume, a new generation of biologists have taken up this challenge. Using advances in both molecular genetic and statistical techniques, evolutionary geneticists have made considerable progress in this emerging field. In this volume, a diversity of examples from plant and animal studies provides valuable information for those interested in the genetics and evolution of complex traits.

The study of evolutionary adaptation returns to the center stage of biology with this important volume. This innovative treatise discusses new developments in adaptation, with new methods, and new theoretical foundations, achievements, and prospects for a rich intellectual future. It is an insightful reintroduction to the themes that Darwin and his successors regarded as central to any profound understanding of biology.

The data of evolutionary biology have changed in a very radical way in recent years, the most significant input to this revolution being the advances made in developmental genetics. Another recent development is a noticeable shift away from extreme specialization in evolutionary biology. In this, we are perhaps to be reminded of George Gaylord Simpson's comments: "evolution is an incredibly complex but at the same time integrated and unitary process." The main objective of this book is to illustrate how natural adaptive systems evolve as a unity--with the particular objective of identifying and merging several special theories of evolution within the framework of a single general theory. The Evolution of Adaptive Systems provides an interdisciplinary overview of the general theory of evolution from the standpoint of the dynamic behavior of natural adaptive systems. The approach leads to a radically new fusion of the diverse disciplines of evolutionary biology, serving to resolve the considerable degree of conflict existing between different schools of contemporary thought. The book is a timely volume written by a natural historian with a broad view of biology The author draws examples from a large range of organisms from many different habitats and niches where interesting adaptations have evolved Probes deeply into mechanisms of evolution such as developmental genetics, morphogenesis, chromosome structure, and cladogenesis Clear definition of terms, with illustrations visualizing the main theoretical structures, and point-by-point summaries clearly stating the principal conclusions

Since its origin in the early 20th century, the Modern Synthesis theory of evolution has grown to become the orthodox view on the process of organic evolution. Its central defining feature is the prominence it accords to genes in the explanation of evolutionary dynamics. Since the advent of the 21st century, however, the Modern Synthesis has been subject to repeated and sustained challenges. These are largely empirically driven. In the last two decades, evolutionary biology has witnessed unprecedented growth in the understanding of those processes that underwrite the development of organisms and the inheritance of characters. The empirical advances usher in challenges to the conceptual foundations of evolutionary theory. The extent to which the new biology challenges the Modern Synthesis has been the subject of lively debate. Many current commentators charge that the new biology of the 21st century calls for a revision, extension, or wholesale rejection of the Modern Synthesis Theory of evolution. Defenders of the Modern Synthesis maintain that the theory can accommodate the exciting new advances in biology. The original essays collected in this volume survey the various challenges to the Modern Synthesis arising from the new biology of the 21st century. The authors are evolutionary biologists, philosophers of science, and historians of biology from Europe and North America. Each of the essays discusses a particular challenge to the Modern Synthesis treatment of inheritance, development, or adaptation. Taken together, the essays cover a spectrum of views, from those that contend that the Modern Synthesis can rise to the challenges of the new biology, with little or no revision required, to those that call for the abandonment of the Modern Synthesis. The collection will be of interest to researchers and students in evolutionary biology, and the philosophy and history of the biological sciences.

Pillars of Evolution provides a fresh and provocative perspective on adaptive evolution. Readers new to the study of evolution will find a refreshing new insight that establishes evolutionary biology as a rigorous and predictive science, whilst practicing biologists will discover a provocative book that challenges traditional approaches. The book begins by leading readers through the mechanics of heredity, reproduction, movement, survival, and development. With that framework in place, it then explores the numerous ways that traits emerge from the interactions between genetics, development, and the environment. The key message is that adaptive changes in traits (and their underlying allelic frequencies) evolve through the traits' functions and their connection with fitness. The complex mappings from genes-to-traits-to-fitness are characterized in the structure of evolution. A single "structure matrix" describes why individuals vary in the values of adaptive traits, their ability to perform the function of those traits, and in the fitness they accrue. Fitness depends on how organisms interact with and perceive their environment in time and space. These relationships are made explicit in spatial, temporal, and organizational scale that also sets the stage for the crucially important role that ecology always plays in evolution. The ecological hallmarks of density- and frequency-dependent interactions allow the authors to explore new and exciting insights into evolution's dynamics. The theories and principles are then brought together in a final synthesis on adaptation. The book's unique approach unites genetic, development, and environmental influences into a single comprehensive treatment of the eco-evolutionary process.

Patterns of adaptation in the past and the genetic basis of traits likely to be under selection in the dynamically changing environment are also discussed in relation to these responses.".

It will be an invaluable tool for anyone interested or working in molecular or evolutionary biology, and for those studying the implications of our rapidly increasing knowledge of the genomes of organisms."--BOOK JACKET.