Guide For Diagnostic Nuclear Medicine And Radiopharmaceutical Therapy

The thoroughly updated new edition of the authoritative reference in Radiopharmaceutical Sciences The second edition of Handbook of Radiopharmaceuticals is a comprehensive review of the field, presenting up-to-date coverage of central topics such as radionuclide production, synthetic methodology, radiopharmaceutical development and regulations, and a wide range of practical applications. A valuable reference work for those new to the Radiopharmaceutical Sciences and experienced professionals alike, this volume explores the latest concepts and issues involving both targeted diagnostic and therapeutic radiopharmaceuticals. Contributions from a team of experts from across sub-disciplines provide readers with an immersive examination of radiochemistry, nuclear medicine, molecular imaging, and more. Since the first edition of the Handbook was published, Nuclear Medicine and Radiopharmaceutical Sciences have undergone major changes. New radiopharmaceuticals for diagnosis and therapy have been approved by the FDA, the number of clinical PET and SPECT scans have increased significantly, and advances in Artificial Intelligence have dramatically improved research techniques. This fully revised edition reflects the current state of the field and features substantially updated and expanded content. New chapters cover topics including current Good Manufacturing Practice (cGMP), regulatory oversight, novel approaches to quality control—ensuring that readers are informed of the exciting developments of recent years. This important resource: Features extensive new and revised content throughout Covers key areas of application for diagnosis and therapy in oncology, neurology, and cardiology Emphasizes the multidisciplinary nature of Radiopharmaceutical Sciences Discusses how drug companies are using modern radiopharmaceutical imaging techniques to support drug discovery Examines current and emerging applications of Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) Edited by recognized experts in radiochemistry and PET imaging, Handbook of Radiopharmaceuticals: Radiochemistry and Applications, 2 nd Edition is an indispensable reference for post-doctoral fellows, research scientists, and professionals in the pharmaceutical industry, and for academics, graduate students, and newcomers in the field of radiopharmaceuticals.

This book, now in an extensively revised second edition, summarizes the basic principles of nuclear medicine and describes the clinical applications of commonly used nuclear medicine procedures and techniques. Readers will find clear explanation of clinical indications, the pathophysiological basis of functional procedures, and the complementary role of nuclear medicine and molecular imaging in relation to diagnostic radiology. Throughout, emphasis is placed on the added diagnostic value offered by the new hybrid imaging modalities. The various therapeutic applications of nuclear medicine are also discussed. Compared with the first edition, technical details have been significantly simplified. The book will be an ideal introduction to nuclear medicine for medical students and will serve as an excellent quick reference for referring physicians, enabling them to utilize this modern medical specialty more efficiently.

Nuclear Medicine Therapy presents the state of the art in targeted radionuclide therapy, both in clinical practice and contemporary clinical investigation and trials. With contributions from an internationally-distinguished group of physicians and scientists, the book is devoted entirely to the use of nuclear medicine techniques and technology for therapy of malignant and benign diseases. Individual chapters cover the scientific principles and clinical applications of radionuclide therapy and the state of clinical trials of agents currently under investigation in the therapy of tumors involving virtually every organ system. Due to overlapping interest in techniques, indications, and clinical use, the development of radionuclide therapy attracts considerable input from other medical specialists whose collaboration is essential, including radiation and medical oncologists, hematologists, diagnostic radiologists, hepatologists, endocrinologists, and rheumatologists. And because radionuclide therapy is a rapidly evolving field of nuclear medicine, it is the aim of this volume to appeal to all specialists involved in targeted radionuclide therapy and to contribute to the standardization of the practice globally.

A tactical guide for radiologists and nuclear medicine physicians, Diagnostic Imaging: Nuclear Medicine, Second Edition is practical, easy-to-use, and in-touch with the realities of multimodality diagnostic imaging. This comprehensive yet accessible reference addresses the most appropriate nuclear medicine options available to answer specific clinical questions within the framework of all imaging modalities. Sweeping updates include a complete reorganization, new differential diagnoses based on findings, and new chapters on physics and Nuclear Regulatory Commission guidelines. User-friendly bulleted text and a uniform chapter layout allow fast and effortless access to the crucial knowledge you need! Time-saving reference features include bulleted text, a variety of test data tables, key facts in each chapter, 2,000 full-color annotated images, and an extensive index Expanded coverage of the most important topics and trends in nuclear medicine including Recently revised radioactive iodine therapy guidelines for hyperthyroidism and thyroid cancer New bone tumor therapy radium-223 (currently indicated for treatment of painful bone metastases in prostate cancer) New I-123 ioflupane dopamine transporter imaging for diagnosis of parkinsonian syndromes F-18 PET/CT bone scan (particularly its indication for nonaccidental trauma in children) Meticulous updates throughout reflect the latest advances as well as all study guide topics listed for the new American Board of Radiology exam, including physics and Nuclear Regulatory Commission guidelines Expert Consult eBook version included with purchase allows you to search all of the text, figures, and references from the book on a variety of devices

The book covers all the radiation safety aspects while working with unsealed radionuclides. Radiation safety plays a significant role in routine nuclear medicine practices and is necessary to protect occupational workers, patients, members of the general public and the environment. A fair knowledge of radiation safety is expected from all nuclear medicine professionals. Chapters include basics of radiation physics, biological bases of radiation protection, planning and design of nuclear medicine facilities, cyclotron and high dose therapy facilities, radiation safety considerations in nuclear medicine, cyclotron while preparing radiopharmaceuticals. It also includes the working mechanism of radiation detectors, quality assurance of positron emission tomography (PET) and gamma camera, including single photon emission computed tomography (SPECT), emergency preparedness plan, nuclear medicine and CT dosimetry, transport regulations, the role of national regulatory authorities and radioactive waste management. The last chapter provides probable model questions asked in the radiological safety officer certification examination and includes 250 multiple-choice questions (MCQs), 100 true or false, 60 fill in the blanks, and 40 match the following questions. The book is written in a simple language for a better understanding of the occupational workers of any grade. It serves as reference material for nuclear medicine professionals on radiation safety, related to planning, quality assurance, dosimetry and various regulations pertaining to nuclear medicine. It is a ready reckoner for the students pursuing a degree/diploma in nuclear medicine and preparing for certification courses in radiation safety to understand the subject matter along with options to attempt practice questions.

Covering both the fundamentals and recent developments in this fast-changing field, Essentials of Nuclear Medicine and Molecular Imaging, 7th Edition, is a must-have resource for radiology residents, nuclear medicine residents and fellows, nuclear medicine specialists, and nuclear medicine technicians. Known for its clear and easily understood writing style, superb illustrations, and self-assessment features, this updated classic is an ideal reference for all diagnostic imaging and therapeutic patient care related to nuclear medicine, as well as an excellent review tool for certification or MOC preparation. Provides comprehensive, clear explanations of everything from principles of human physiology, pathology, physics, radioactivity, radiopharmaceuticals, radiation safety, and legal requirements to hot topics such as new brain and neuroendocrine tumor agents and hybrid imaging, including PET/MR and PET/CT. Covers the imaging of every body system, as well as inflammation, infection and tumor imaging; pearls and pitfalls for every chapter; and pediatric doses and guidelines in compliance with the Image Gently and Image Wisely programs. Features a separate self-assessment section on differential diagnoses, imaging procedures and artifacts, and safety issues with unknown cases, questions, answers, and explanations. Includes new images and illustrations, for a total of 430 high-quality, multi-modality examples throughout the text. Reflects recent advances in the field, including updated nuclear medicine imaging and therapy guidelines • Updated dosimetry values and effective doses for all radiopharmaceuticals with new values from the 2015 International Commission on Radiological Protection • Updated information regarding advances in brain imaging, including amyloid, dopamine transporter and dementia imaging • Inclusion of Ga-68 DOTA PET/CT for neuroendocrine tumors • Expanded information on correlative and hybrid imaging with SPECT/CT • New myocardial agents • and more. Contains extensive appendices including updated comprehensive imaging protocols for routine and hybrid imaging, pregnancy and breastfeeding guidelines, pediatric dosages, non-radioactive pharmaceuticals used in interventional and cardiac stress imaging, and radioactivity conversion tables.